Protein Alignment Nhe3 and si:dkey-162b23.4

DIOPT Version :10

• Sequence 1: NP_723202.2
• Gene: Nhe3 / 33939
• FlyBaseID: FBgn0028703
• Length: 711
• Species: Drosophila melanogaster
• Sequence 2: XP_699710.2
• Gene: si:dkey-162b23.4 / 571064
• ZFINID: ZDB-GENE-110411-203
• Length: 564
• Species: Danio rerio
• Alignment Length: 367
• Identity: 70/367 - (19%)
• Similarity: 125/367 - (34%)
• Gaps: 96/367 - (26%)

  Fly    12 LAPGCSATDTDIALDAKATLNHRIQSLDLLVFVFLLALTVLTIWLFKHHRVSWLHETGLAVIYGL 76
            :|.|.......:.||:||....:...|.|.:|..:.....:.:..:....:.|:....|..:.|.
Zfish   198 IALGVILVKAGLELDSKALKKLKAVCLRLSMFPLIFEAATMAVMSYLILGLPWIWGFILGFVLGA 262

  Fly    77 IVGAIIRYAGTSATLVHMQ---VEPQGVPT--------------------YSDKLPPDTLW---F 115
            :..|::   ..|..|:|.|   :| ||:||                    ........::|   .
Zfish   263 VTPAVV---VPSMLLLHRQGYGLE-QGIPTLLMAACSVDDIIAITCFTTCLGIAFATGSVWLNVL 323

  Fly   116 RYPVNQTNGTKPPEGIKTYAYVFRGQVHDVDENEIDLKATFDPEVFFNIILPPIIFYAGYSLKKK 180
            |.|:....|......:..:.:.|..:    |:..:.||.:|       ::|...:|        .
Zfish   324 RGPLEVLGGAVTGVALGFFLHYFPSR----DQRNLVLKRSF-------LVLGLSVF--------A 369

  Fly   181 YFFRNLGAILTFAIVGTTLSAFLIGGFMYGCVKLMPKYLSSSFTFL-DSLYFGAL-----ISPTD 239
            .|..|:..|.....:.|.:.|| :.|..:|..|...:.:...|..: ..|.||.:     ||..:
Zfish   370 LFGSNVAGIPGAGGLCTLVLAF-VAGIGWGRAKASVEAVVERFWLVFQPLLFGLIGAEIVISSLE 433

  Fly   240 PLTILAIFNDLRVDVNLYALVLGESVLNDAVAIVLSGAIQNYGEHYSNTGEFETTAFL------- 297
            ..|:.         :.:.||.:|.:|......||:..|..|..|..     |.|.|::
Zfish   434 LTTVF---------LGIAALFIGLTVRLLVTFIVVLRAGFNLKEKI-----FVTLAWMPKATVQA 484

  Fly   298 ----------RSLSDF---------FSIFLLSLMIGAAMGCL 320
                      ||..|.         .::.:||::|.|.:|.|
Zfish   485 AIGSTALDMARSKQDLELQKYGMDVLTVAVLSIIITAPIGAL 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nhe3	NP_723202.2	Na_H_Exchanger	155..>531	CDD:470090	40/198 (20%)
si:dkey-162b23.4	XP_699710.2	NhaP	133..553	CDD:439796	70/367 (19%)