Protein Alignment Nhe3 and SPOM_SPAC15A10.06

DIOPT Version :10

• Sequence 1: NP_723202.2
• Gene: Nhe3 / 33939
• FlyBaseID: FBgn0028703
• Length: 711
• Species: Drosophila melanogaster
• Sequence 2: NP_594293.2
• Gene: SPOM_SPAC15A10.06 / 2542747
• PomBaseID: SPAC15A10.06
• Length: 567
• Species: Schizosaccharomyces pombe
• Alignment Length: 610
• Identity: 192/610 - (31%)
• Similarity: 301/610 - (49%)
• Gaps: 84/610 - (13%)

  Fly    20 DTDIALDAKATLNHRIQSLDLLVFVFLLALTVLTIWLFKHHRVSWLHETGLAVIYGLIVGAIIRY 84
            |.|...|  ..|.....|..|.:.:.||...:||.:..:..::..:|||.::|..|::||.|||
pombe    17 DDDDGQD--PALQELYSSWALFILLVLLIGALLTSYYVQSKKIRAIHETVISVFVGMVVGLIIR- 78

  Fly    85 AGTSATLVHMQVEPQGVPTYSDKLPPDTLWFRYPVNQTNGTKPPEGIKTYAYVFRGQVHDVDENE 149
                       |.|                               |:             :.:|.
pombe    79 -----------VSP-------------------------------GL-------------IIQNM 88

  Fly   150 IDLKATFDPEVFFNIILPPIIFYAGYSLKKKYFFRNLGAILTFAIVGTTLSAFLIGGFMYGCVKL 214
            :...:|:    |||::|||||..:||.|.:..||||:|.|||||..||.:||..:|..:|  :..
pombe    89 VSFHSTY----FFNVLLPPIILNSGYELHQSNFFRNIGTILTFAFAGTFISAVTLGVLVY--IFS 147

  Fly   215 MPKYLSSSFTFLDSLYFGALISPTDPLTILAIFNDLRVDVNLYALVLGESVLNDAVAIVLSGAIQ 279
            ...:.:.|.||:::|..||.:|.|||:|:|||||..:||..||.::.|||:||||||||:...:|
pombe   148 FLNFENLSMTFVEALSMGATLSATDPVTVLAIFNSYKVDQKLYTIIFGESILNDAVAIVMFETLQ 212

  Fly   280 NYGEHYSNTGEFETTAFLRSLSDFFSIFLLSLMIGAAMGCLTALMTKFTRVRDFPLLESALFVLM 344
            .:   ...|..|.|  ....:..|...|.:||:||.::|.:|||:.|::.:|.:|.:||.:.:||
pombe   213 QF---QGKTLHFFT--LFSGIGIFIITFFISLLIGVSIGLITALLLKYSYLRRYPSIESCIILLM 272

  Fly   345 SYSTFLLAEATELTGVVAVLFCGICQAHYTYNNLSEDSRQRTKQIFELLNFLAENFIFSYIGVSM 409
            :|:::..:....::|||::|||||...||.:.|:|..::..||.:|.:|..|:|||||.|:|:|:
pombe   273 AYTSYFFSNGCHMSGVVSLLFCGITLKHYAFFNMSYKAKLSTKYVFRVLAQLSENFIFIYLGMSL 337

  Fly   410 FTFPKHHFDAGFIITAFICAAIGRAVNVYPLSWLLNIKRKPK-------ISTNFQHMLFFAGLRG 467
            ||.....:...||:...:.....|.:||:|||.|||...:.:       |..::|.|||:|||||
pombe   338 FTQVDLVYKPIFILITTVAVTASRYMNVFPLSNLLNKFHRQRNGNLIDHIPYSYQMMLFWAGLRG 402

  Fly   468 AMSFALAIRNTVSDERQTMLTATSLIVIFTVVIQGGAANFLLNWLKIPVG----VDDETE-QLNN 527
            |:..||| .....:..||:...|.::|:.|::|.||....:|..|.|..|    ||.:|| .:..
pombe   403 AVGVALA-AGFEGENAQTLRATTLVVVVLTLIIFGGTTARMLEILHIETGVAADVDSDTEIGMLP 466

  Fly   528 YQVHSVYNSMDNSHPQTSDGYLQDVEGGGVNRNKMRLSGGTDTNLDTPVDGTNGSLGGASGGRRR 592
            :|....:: ::||..:.||...:.|........:....|.....|...|..|......|:|...:
pombe   467 WQQSPEFD-LENSAMELSDASAEPVVVDQQFTTEHFDEGNIAPTLSKKVSSTFEQYQRAAGAFNQ 530

  Fly   593 NSHEKAILARIW-GNFDTKYMKPLL 616
            ..|........| ..||.:.:||:|
pombe   531 FFHSSRDDQAQWLTRFDEEVIKPVL 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nhe3	NP_723202.2	Na_H_Exchanger	155..>531	CDD:470090	150/387 (39%)
SPOM_SPAC15A10.06	NP_594293.2	Na_H_Exchanger	28..>451	CDD:470090	164/490 (33%)