Protein Alignment Nhe3 and slc-9B.1

DIOPT Version :10

• Sequence 1: NP_723202.2
• Gene: Nhe3 / 33939
• FlyBaseID: FBgn0028703
• Length: 711
• Species: Drosophila melanogaster
• Sequence 2: NP_509724.1
• Gene: slc-9B.1 / 181236
• WormBaseID: WBGene00009617
• Length: 516
• Species: Caenorhabditis elegans
• Alignment Length: 471
• Identity: 79/471 - (16%)
• Similarity: 161/471 - (34%)
• Gaps: 142/471 - (30%)

  Fly   119 VNQTNGTKPPEGIKTYAYVFRGQVHDVDENEIDLKATFDP-----------------EVFFNIIL 166
            ||..|.|.....:::...:|...|..:...:|.......|                 :.||  :.
 Worm    53 VNPVNATNEDVTVRSIFVIFILLVAGIFAAKISKALRLPPLFGCLALGIIIKNITVFDQFF--VF 115

  Fly   167 PP-------------IIFYAGYSLKKKYFFRN------LGAILTFA-IVGTTLSAFLIGGFMYGC 211
            ||             ||...|.:....:.:.|      :|.:.... |:..|::::.|
 Worm   116 PPFVETMIRKVALVMIIVRWGLATDIHFLYENALMPVTIGLVTAIGEIIAVTIASYFI------- 173

  Fly   212 VKLMPKYLSSSFTFLDSLYFGALISPTDP-LTILAIFND--------LRVDVNLYALVLGESVLN 267
                     .:.:|:.|::...::....| :|:.|:.|.        .|:..|:.|:...:::..
 Worm   174 ---------LNISFVMSIFCALILVTVSPAVTVPAMINFKEKQLGSLKRIPENILAICCVDNLFC 229

  Fly   268 DAVAIVLSGAIQNYGEHYSNTGEFETTAFLRSLSDFFSIFLLSLMIGAAMGCLTALM-------- 324
            ..:.:|||..|       .......||..|.:.|..|             ||:..::
 Worm   230 VILFMVLSSII-------FTDAPIATTILLNAGSIVF-------------GCIGGIVLGWILWRF 274

  Fly   325 -------TKFTRVRDFPLLESALFVLMSYSTFLLAEATELTGVVAVLFCGICQAHYTYNNLSEDS 382
                   |:|.|:    .|...:.:.:...|:|:..:  .:|.:|.|......|    .....|:
 Worm   275 PRSDAPHTQFARI----TLLGTICIAVVIGTYLIKYS--CSGFLAALITSAMSA----MQWKADN 329

  Fly   383 RQRTKQIFELLNFLAENF----IFSYIGVSMFTFPKHHFDAGFII--TAFIC---AAIGRAVN-- 436
            :::.:.:.....::.::|    :|..:|:.        ||...:.  ..|:|   .|||..|.
 Worm   330 KEKLECVESTYKYIWDSFALPLLFICLGMK--------FDCSTLTWEIVFLCIAVIAIGLLVRTI 386

  Fly   437 ---VYPLSWLLNIKRKPKISTNFQHMLFFAGLRGAMSFALAIRNT----VSDERQTMLTATSLIV 494
               :..||..:|.|.:..::.:   :|..|..:..::..|.:..|    ::.:...:|.|..|.|
 Worm   387 LVMLVTLSSHINFKEQIVVALS---LLPRATFQADLAPTLLLMATPFPDMAKDAALILKAAILSV 448

  Fly   495 IFTVVIQGGAANFLLN 510
            :.|..|    .:.|||
 Worm   449 LITAPI----FDILLN 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nhe3	NP_723202.2	Na_H_Exchanger	155..>531	CDD:470090	72/435 (17%)
slc-9B.1	NP_509724.1	NhaP	68..>454	CDD:439796	71/444 (16%)