Protein Alignment cort and cdc20

DIOPT Version :9

• Sequence 1: NP_001260144.1
• Gene: cort / 33937
• FlyBaseID: FBgn0000351
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_988945.1
• Gene: cdc20 / 394542
• XenbaseID: XB-GENE-970663
• Length: 507
• Species: Xenopus tropicalis
• Alignment Length: 558
• Identity: 116/558 - (20%)
• Similarity: 196/558 - (35%)
• Gaps: 169/558 - (30%)

  Fly     8 CDSPNKNSKLDKKSLTPFKKVRRKNWKQEAAYKSDTSKGQEVSYV-----GERFIPNR--FEREN 65
            |.|  .|:..:..:::|.|...|.:...:...|:....|.::...     |:||||||  .:.:.
 Frog    37 CSS--LNTSANTSTMSPMKTSNRSHSSSKTPSKTPGKSGPKMQGTPSRAGGDRFIPNRSAMQMDV 99

  Fly    66 IEFNLKYIGKRKERDILETGVTLTASYWRQSGFISNINRTFGIGERRLFQFSSQQGTRSRVVDND 130
            ..|.|     .||.:..:|..|...   :|..:..|:| .|.:.|.::.:...:
 Frog   100 ASFLL-----CKENEPADTSPTKKE---QQKAWAMNLN-GFDMEEAKILRLGGR----------- 144

  Fly   131 SADSDWPCNPRARPYAIQN------ATHEMPGICSPV-------------------DY--NMMDW 168
                     |:..|...||      :....||.....                   ||  |::||
 Frog   145 ---------PQNAPEGYQNNLKVLYSQKTTPGSSKKTGRYIPSMPDRVLDAPDIRNDYYLNLIDW 200

  Fly   169 SSGGMVAMSSGQDVMLWRNLDES-----TMVFSVESPTSLKYSPDGKHLAIGCMDRNYPVLDLWE 228
            ||...:|::....|.||......     .|..|.|..:|:.:..:|.:||:|..:..   :.||:
 Frog   201 SSQNFLAVALNDSVYLWNYATGDIILLLQMEHSEEYISSVSWIKEGNYLAVGTSNSE---VQLWD 262

  Fly   229 VRSPTEFLVSYRKLFFKSMGYISCIEWSHDGKEVICGTQCGVI----IVLAMPTLNTLMQLREHR 289
            |:.....    |.:...| ..:..:.|::  ..:..|::.|.|    :.:|...::|   |..|.
 Frog   263 VQQQKRL----RNMTSHS-SRVGALSWNN--HILSSGSRTGHIHHHDVRVAQHHVST---LTGHT 317

  Fly   290 HTVKKMKFAPTHKYFASSDTDGKIFIFDAVLKVRLLKLDGRSIVFD----------------WHP 338
            ..|..:|::|..:|.||...|..:.::..|        .|.|..|.                |.|
 Frog   318 QEVCGLKWSPDGRYLASGANDNLVNVWPCV--------QGDSGEFSPVQTFTQHQGAVKAVAWCP 374

  Fly   339 WTGEDLAV-AERSPASIFIFNIPRRQFVASYRRRDDRIVIKTLTYSKITGELLVNVIRRDDADLA 402
            |....||. ...|...|.|:|:                         .:|..|.:|    |....
 Frog   375 WQSNVLATGGGTSDRHIRIWNV-------------------------CSGTCLNSV----DTHSQ 410

  Fly   403 VCEI-------------------LVL---ASLNRVVDLMSHQDRGTLFLMWNPDGTKIATGGLDD 445
            ||.|                   |||   .::.||.:|..|..| .|.|..:|||..:|:...|:
 Frog   411 VCSILWSTNYKELISGHGFAQNQLVLWKYPTMTRVTELKGHTAR-VLNLAISPDGCTVASAAADE 474

  Fly   446 TFSLWNFFPTYKREAILRKQEQKAKDKCSSLSLYKGIR 483
            |..||..|..   :.:.:|:::||:.  |...:::.||
 Frog   475 TLRLWKCFEV---DPVTKKEKEKARS--SKSIIHQSIR 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cort	NP_001260144.1	WD40	<166..453	CDD:225201	74/334 (22%)
		WD40	166..451	CDD:295369	73/332 (22%)
		WD40 repeat	201..244	CDD:293791	9/42 (21%)
		WD40 repeat	251..287	CDD:293791	7/39 (18%)
		WD40 repeat	292..326	CDD:293791	8/33 (24%)
		WD40 repeat	334..369	CDD:293791	10/51 (20%)
		WD40 repeat	377..419	CDD:293791	12/63 (19%)
		WD40 repeat	427..466	CDD:293791	12/38 (32%)
cdc20	NP_988945.1	WD40	198..480	CDD:238121	73/332 (22%)
		WD40 repeat	237..272	CDD:293791	9/41 (22%)
		WD40 repeat	278..315	CDD:293791	7/41 (17%)
		WD40 repeat	320..361	CDD:293791	11/48 (23%)
		WD40 repeat	368..406	CDD:293791	12/66 (18%)
		WD40 repeat	411..449	CDD:293791	8/37 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19918
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100