Protein Alignment cort and fzr1a

DIOPT Version :10

• Sequence 1: NP_523494.1
• Gene: cort / 33937
• FlyBaseID: FBgn0000351
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_956547.1
• Gene: fzr1a / 393223
• ZFINID: ZDB-GENE-040426-712
• Length: 495
• Species: Danio rerio
• Alignment Length: 521
• Identity: 116/521 - (22%)
• Similarity: 192/521 - (36%)
• Gaps: 162/521 - (31%)

  Fly    53 GERFIPNR--------FERENIEFNLKYIGKRKERDILETGVTLTASYWRQSGFISNINRTFGIG 109
            |:||||:|        |.|.|.........|:.:....::|.....:|   |..:.  |...|.|
Zfish    47 GDRFIPSRAGANWSINFHRINENEKSPSQNKKTKDATSDSGKADGLAY---SALLK--NELLGAG 106

  Fly   110 -------------------ERR-LFQFSSQQGTRSRVVDNDSADSDWPCNPRAR----------- 143
                               ||| ||.:|.   :..|...:|::.|.:..:|.:.
Zfish   107 IEKVLDPQTEDRRLQPSTPERRSLFSYSL---SAKRSTPDDNSVSPYSLSPVSSKSQKLLRSPRK 168

  Fly   144 --------PYAIQNATHEMPGICSPVDYNMMDWSSGGMVAMSSGQDVMLW--------RNLDEST 192
                    |:.:.:|    |.:......|::||||..::::..|..|.||        |..|
Zfish   169 PTRKISKIPFKVLDA----PELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCD--- 226

  Fly   193 MVFSVE--SPTSLKYSPDGKHLAIGCMDRNYPVLDLWEVRSPTEFLVSYRKLFFKSMGY---ISC 252
              .|||  |.||:.:|..|..:|:|   .:...:.:|:..:        .|..|...|:   :..
Zfish   227 --LSVEGDSVTSVGWSERGNLVAVG---THKGFVQIWDATA--------GKKLFALEGHTARVGA 278

  Fly   253 IEWSHDGKEVICGTQCGVIIV--LAMPTLNTLMQLREHRHTVKKMKFAPTHKYFASSDTDGKIFI 315
            :.|:.|  ::..|::..:|:.  :..|.|.:..:|:.||..|..:|::..|:..||...|.|:.:
Zfish   279 LAWNAD--QLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLV 341

  Fly   316 FD--AVLKVR--------------------LLKLDG----RSIVFDWHPWTGEDLAVAERSPASI 354
            ::  :||.::                    ||...|    |.|.| |:..|.:.|...
Zfish   342 WNHSSVLPMQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRF-WNTLTAQPLQCI------- 398

  Fly   355 FIFNIPRRQFVASYRRRDDRIVIKTLTYSKITGELLVNVIRRDDADLAVCEILV--LASLNRVVD 417
                             |....:..|.:||.|.||:      .....:..:|||  ..||.:|..
Zfish   399 -----------------DTGSQVCNLAWSKHTNELV------STHGYSQNQILVWKYPSLTQVAK 440

  Fly   418 LMSHQDRGTLFLMWNPDGTKIATGGLDDTFSLWNFFPTYKREAILRKQEQKAKDKCSSLSLYKGI 482
            |..|..| .|:|..:|||..|.||..|:|...||.|          .:.:..|:..|.|:|:..|
Zfish   441 LTGHSYR-VLYLAMSPDGEAIVTGAGDETLRFWNVF----------SKTRSTKESVSVLNLFTRI 494

  Fly   483 R 483
            |
Zfish   495 R 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cort	NP_523494.1	WD40	<168..451	CDD:441893	76/325 (23%)
		WD40 repeat	201..244	CDD:293791	8/42 (19%)
		WD40 repeat	251..287	CDD:293791	7/37 (19%)
		WD40 repeat	292..326	CDD:293791	10/55 (18%)
		WD40 repeat	334..369	CDD:293791	4/34 (12%)
		WD40 repeat	377..419	CDD:293791	12/43 (28%)
		WD40 repeat	427..466	CDD:293791	13/38 (34%)
fzr1a	NP_956547.1	WD40	<202..474	CDD:441893	74/321 (23%)
		WD40 repeat	234..271	CDD:293791	9/47 (19%)
		WD40 repeat	277..313	CDD:293791	7/37 (19%)
		WD40 repeat	318..354	CDD:293791	9/35 (26%)
		WD40 repeat	361..399	CDD:293791	9/62 (15%)
		WD40 repeat	404..442	CDD:293791	12/43 (28%)
		WD40 repeat	448..489	CDD:293791	15/50 (30%)