Protein Alignment cort and fzy

DIOPT Version :9

• Sequence 1: NP_001260144.1
• Gene: cort / 33937
• FlyBaseID: FBgn0000351
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_477501.1
• Gene: fzy / 34968
• FlyBaseID: FBgn0001086
• Length: 526
• Species: Drosophila melanogaster
• Alignment Length: 537
• Identity: 120/537 - (22%)
• Similarity: 192/537 - (35%)
• Gaps: 173/537 - (32%)

  Fly    10 SPNKNS--KLDKKSLTPFKKVRRKNWKQEAAYKSDTSKGQEVSYVGERFIPNR----FERENIEF 68
            :|.|:|  |..|.:.||                |.|..|      |:||||||    ||..:...
  Fly    63 TPGKSSEGKTKKSNTTP----------------SKTPGG------GDRFIPNRAATNFELAHFLV 105

  Fly    69 NLKYIGKRKERDILETGVTLTASYWRQSGFISNINRTFGIGERRLFQFSSQQGTRSRVVD----- 128
            |.....|..|.:...|.              ||.|.:       ..|.|:.:|.|.:::.
  Fly   106 NKDSGDKSDEENDKATS--------------SNSNES-------NVQASAHKGDRQKLISEVAQV 149

  Fly   129 NDSADSDWPCNPRARPYAIQNATHEMP-----GICSPV------------------------DY- 163
            .||......|.....|.|.:  ||..|     .|.:|:                        ||
  Fly   150 GDSKGGRILCYQNKAPAAPE--THNNPLKVVYSIKTPISTKSGSRYIPTTSERILDAPDFINDYY 212

  Fly   164 -NMMDWSSGGMVAMSSGQDVMLWR----NLDESTMVFSVESPTSLKYSPDGKHLAIGCMDRNYPV 223
             |:||||:..:||::.|..|.||.    |:::.|.....:...||.:..:|:.||||   .:...
  Fly   213 LNLMDWSADNIVAVALGSCVYLWNAQTGNIEQLTEFEEGDYAGSLSWIQEGQILAIG---NSTGA 274

  Fly   224 LDLWEVRSPTEFLVSYRKLFFKSMGYISCIEWSHDGKEVICGTQCGVIIVLAMPTLNTLMQLREH 288
            ::||:...     |...::.......:..:.|  :...|..|::.|.|:       :..::.|||
  Fly   275 VELWDCSK-----VKRLRVMDGHSARVGSLAW--NSFLVSSGSRDGTIV-------HHDVRAREH 325

  Fly   289 R------HT--VKKMKFAPTHKYFASSDTDGKIFIFDAV------------------LKVRLLKL 327
            :      ||  |..:|::...||.||...|..:.::.|.                  ..||.|.
  Fly   326 KLSTLSGHTQEVCGLKWSTDFKYLASGGNDNLVNVWSAASGGVGTATDPLHKFNDHQAAVRALA- 389

  Fly   328 DGRSIVFDWHPWTGEDLA----VAERSPASIFIFNIPRRQFVASYRRRDDRIVIKTLTYSKITGE 388
                    |.||....||    .|:|   .|..:|:.....:.|.   |.:..:.:|.:|:...|
  Fly   390 --------WCPWQPSTLASGGGTADR---CIKFWNVNNGTLMKSV---DSKSQVCSLLFSRHYKE 440

  Fly   389 LLV------NVIRRDDADLAVCEILVLASLNRVVDLMSHQDRGTLFLMWNPDGTKIATGGLDDTF 447
            |:.      |.:          .|....::.:..||..|..| .|.:..:|||:.:.:.|.|:|.
  Fly   441 LISAHGFANNQL----------TIWKYPTMVKQADLTGHTSR-VLQMAMSPDGSTVISAGADETL 494

  Fly   448 SLWNFF---PTYKREAI 461
            .|||.|   |...::|:
  Fly   495 RLWNCFAPDPLASKKAV 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cort	NP_001260144.1	WD40	<166..453	CDD:225201	74/326 (23%)
		WD40	166..451	CDD:295369	72/324 (22%)
		WD40 repeat	201..244	CDD:293791	10/42 (24%)
		WD40 repeat	251..287	CDD:293791	5/35 (14%)
		WD40 repeat	292..326	CDD:293791	10/51 (20%)
		WD40 repeat	334..369	CDD:293791	10/38 (26%)
		WD40 repeat	377..419	CDD:293791	7/47 (15%)
		WD40 repeat	427..466	CDD:293791	13/38 (34%)
fzy	NP_477501.1	WD40	<208..500	CDD:225201	77/334 (23%)
		WD40	216..498	CDD:238121	72/324 (22%)
		WD40 repeat	256..291	CDD:293791	10/42 (24%)
		WD40 repeat	297..332	CDD:293791	8/43 (19%)
		WD40 repeat	337..373	CDD:293791	8/35 (23%)
		WD40 repeat	386..424	CDD:293791	12/52 (23%)
		WD40 repeat	429..467	CDD:293791	7/47 (15%)
		WD40 repeat	473..513	CDD:293791	13/39 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0305
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19918
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910