Protein Alignment cort and fzy

DIOPT Version :10

• Sequence 1: NP_523494.1
• Gene: cort / 33937
• FlyBaseID: FBgn0000351
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: XP_061510621.1
• Gene: fzy / 1271249
• VectorBaseID: AGAMI1_009021
• Length: 566
• Species: Anopheles gambiae
• Alignment Length: 571
• Identity: 134/571 - (23%)
• Similarity: 220/571 - (38%)
• Gaps: 163/571 - (28%)

  Fly     5 MSVCDSPNKNSKLDKKSLTPFKKVRRKNWKQEAA------YKSDTSKGQEVSY-----------V 52
            :||..:.|.|:.|...:.....|..|||..:..|      :....|||...|.           .
Mosquito    55 LSVSMTGNANNTLQLSTTVNSLKTPRKNGGKGTASSASKKFSQTPSKGPTASSNTNGNAQNQPGG 119

  Fly    53 GERFIPNRFERENIEFNL-KYIGKRKERDILE-------------------TGVTLTASYWRQSG 97
            |:||||:   |...:|:| .||.|:......|                   :.:.::.....:..
Mosquito   120 GDRFIPS---RTATDFDLGHYIVKQGTASNEEGEGGGNLENEEGAAGGGPTSNIPVSPKQSERMK 181

  Fly    98 FISNINRTFGIGERRLFQFSSQQGTRSRVVDNDSADSDWPCNPRARPYAIQ-------------N 149
            .:|...|...|.::||..|      |::|    .|..:...||....|:::             |
Mosquito   182 SLSEAMRGCDISKQRLLAF------RTKV----PAPPEGHVNPLKAIYSVKTPMSAKSGSRYIPN 236

  Fly   150 ATH---EMPGICSPVDYNMMDWSSGGMVAMSSGQDVMLWRNLDEST--MVFSVES---PTSLKYS 206
            |..   :.|.|.:....|:||||:..::|::.|..|.|| |....|  |:|..|.   ..||.:.
Mosquito   237 APERILDAPEIMNDYYLNLMDWSTDNVIAVALGASVYLW-NAATGTIEMLFENEGNDHACSLSWI 300

  Fly   207 PDGKHLAIGCMDRNYPVLDLWEVRSPTEFLV----SYRKLFFKSMGYISCIEWSHDGKEVIC-GT 266
            .:|..||:|   .:...::||:..:.....|    |.|         :..:.|:   ..|:| |:
Mosquito   301 HEGHILAVG---TSAGTVELWDCENMKRLRVMNGHSAR---------VGVLAWN---SYVLCSGS 350

  Fly   267 QCGVIIVLAMPTLNTLMQLREHR------HT--VKKMKFAPTHKYFASSDTDGKIFIFDAV---- 319
            :.|.|:       |..::.|:|.      ||  |..:|::|..||.||...|..:.::.:.
Mosquito   351 RDGTIV-------NHDVRTRQHNIGVLQGHTQEVCGLKWSPDGKYLASGGNDNLVHVWSSAHGAP 408

  Fly   320 --------------LKVRLLKLDGRSIVFDWHPWTGEDLA----VAERSPASIFIFNIPRRQFVA 366
                          ..:|.|.         |.||....||    .|:|   :|..:|:...|.:.
Mosquito   409 HATGEPLHVFNQHQAAIRALA---------WCPWQPNVLASGGGTADR---TIKFWNVANGQLMN 461

  Fly   367 SYRRRDDRIVIKTLTYSKITGELL-----VNVIRRDDADLAVCEILVLASLNRVVDLMSHQDRGT 426
            |.   |.:..:..|.:||...||:     ||      ..|::.:   ..|:.:.||||.|..| .
Mosquito   462 SV---DTKSQVCGLLFSKTYKELISAHGYVN------NQLSIWK---YPSMMKQVDLMGHTGR-V 513

  Fly   427 LFLMWNPDGTKIATGGLDDTFSLWNFFPTYKREAILRKQEQKA-KDKCSSL 476
            |.:..:|||:.:.:.|.|:|..|||.|..   :.:|.|:|:.| ::|.|.|
Mosquito   514 LQIAMSPDGSTVMSAGADETLRLWNCFAP---DPLLAKKEKSAVREKPSLL 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cort	NP_523494.1	WD40	<168..451	CDD:441893	79/327 (24%)
		WD40 repeat	201..244	CDD:293791	11/46 (24%)
		WD40 repeat	251..287	CDD:293791	7/36 (19%)
		WD40 repeat	292..326	CDD:293791	9/51 (18%)
		WD40 repeat	334..369	CDD:293791	11/38 (29%)
		WD40 repeat	377..419	CDD:293791	11/46 (24%)
		WD40 repeat	427..466	CDD:293791	13/38 (34%)
fzy	XP_061510621.1	None