Protein Alignment Galt and IL11RA

DIOPT Version :10

• Sequence 1: NP_609062.2
• Gene: Galt / 33935
• FlyBaseID: FBgn0263200
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_001136256.1
• Gene: IL11RA / 3590
• HGNCID: 5967
• Length: 422
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 56/284 - (19%)
• Similarity: 78/284 - (27%)
• Gaps: 121/284 - (42%)

  Fly    54 CPGVT-----------RPNGIQTPEY---------------ESTYVFENDFPALVEVVPVPPNND 92
            |||||           .|..:|.|:.               |.||:.:....||...|.:
Human    48 CPGVTAGDPVSWFRDGEPKLLQGPDSGLGHELVLAQADSTDEGTYICQTLDGALGGTVTL----- 107

  Fly    93 DPLFQIA--PARGNCRVMCFHPKSNLTLPTMS--AAEIVVVIDEWI-SQFNELSAKYAWVQIFEN 152
                |:.  |||                |.:|  ||:.......|. ||.:.|..:|.   ....
Human   108 ----QLGYPPAR----------------PVVSCQAADYENFSCTWSPSQISGLPTRYL---TSYR 149

  Fly   153 KGAAMGCSNPH--PHCQIWSCSFLPTEPQLKQERLRAYYATNERPMLADYVERELQRQERIVIEN 215
            |...:|..:..  |....|.|   |.:|      |.|                     .|.|:..
Human   150 KKTVLGADSQRRSPSTGPWPC---PQDP------LGA---------------------ARCVVHG 184

  Fly   216 RDWLVVVPFWATWPFETMLISRNNNKRINDLTAEQRYNLALTIKELTTKYDNLFQCSFPYSMGWH 280
            .:      ||:.:        |.|...:|.|.|..|.        |.....::.:...|..:...
Human   185 AE------FWSQY--------RINVTEVNPLGASTRL--------LDVSLQSILRPDPPQGLRVE 227

  Fly   281 GAPTGPEHAHASSAHWTLHAIYYP 304
            ..|..|....||   ||     ||
Human   228 SVPGYPRRLRAS---WT-----YP 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galt	NP_609062.2	PRK11720	1..350	CDD:236963	56/284 (20%)
IL11RA	NP_001136256.1	IG_like	33..109	CDD:214653	14/69 (20%)
		Ig strand B	44..48	CDD:409533	56/284 (20%)
		Ig strand E	77..81	CDD:409533	0/3 (0%)
		Ig strand F	91..97	CDD:409533	2/5 (40%)
		Ig strand G	102..105	CDD:409533	0/2 (0%)
		FN3	218..310	CDD:238020	9/34 (26%)
		WSXWS motif	304..308
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	335..355
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	398..422