DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Galt and gal7

DIOPT Version :9

Sequence 1:	NP_001260142.1	Gene:	Galt / 33935	FlyBaseID:	FBgn0263200	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_596856.1	Gene:	gal7 / 2541407	PomBaseID:	SPBPB2B2.10c	Length:	369	Species:	Schizosaccharomyces pombe

Alignment Length:	365	Identity:	165/365 - (45%)
Similarity:	228/365 - (62%)	Gaps:	23/365 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 QFVASEHPHRRLNPLNGQWVLVCPHRTQRPWSGQQEKAQKNELPEFDPTNPLCPGVTRPNGIQTP 66
            :|..:|:.|||.|||...:||..|||.:|||.|.:|:.:|::..::|||..||||..|..|.:.|
pombe     5 KFDFTEYSHRRYNPLTDSYVLCSPHRAKRPWQGAKEEIKKDDTVKYDPTCYLCPGNIRATGFENP 69

  Fly    67 EYESTYVFENDFPALVEVVPVPPNNDDP------------LFQIAPARGNCRVMCFHPKSNLTLP 119
            :||:||||.||:||:  .|..|....|.            :|:....:|.|.|:||.|..|||||
pombe    70 KYETTYVFPNDYPAV--RVDQPDYMQDESEITKGNTLKTRMFKTEGVKGKCFVICFCPNHNLTLP 132

  Fly   120 TMSAAEIVVVIDEWISQFNELS-------AKYAWVQIFENKGAAMGCSNPHPHCQIWSCSFLPTE 177
            .|||..|..|::.|...:..|.       .:|.::|||||||:||||||||||.|.|....:|:.
pombe   133 LMSAEAICNVVETWKHLYVTLKKESLEGPIRYKYLQIFENKGSAMGCSNPHPHGQAWCLDVIPSV 197

  Fly   178 PQLKQERLRAYYATNERPMLADYVERELQRQERIVIENRDWLVVVPFWATWPFETMLISRNNNKR 242
            ...:...:..|:..|...:|.|||:.|:..:||||:||..::||||:||.|||||:||::.:.|.
pombe   198 VAQEMCNMTKYFELNNSHLLGDYVKLEMLEKERIVVENDSFIVVVPYWALWPFETLLIAKEHLKS 262

  Fly   243 INDLTAEQRYNLALTIKELTTKYDNLFQCSFPYSMGWHGAPTGPEHAHASSAHWTLHAIYYPPLL 307
            :.:...:|:.:||..:|.|||||||||..|||||||.|.||....:....::.:.:|  :|||||
pombe   263 LEEFEEKQKVDLASALKMLTTKYDNLFNTSFPYSMGLHQAPLYGSNEEVENSWFHMH--FYPPLL 325

  Fly   308 RSASVRKFMVGFELLAMAQRDLTPEQAAQRLREVDGKCHY 347
            |||:|:||.||||:|...|||||.||||.||:|:||:.||
pombe   326 RSATVKKFCVGFEMLGEPQRDLTSEQAAARLQELDGQKHY 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galt	NP_001260142.1	PRK11720	1..350	CDD:236963	165/365 (45%)
Galt	NP_001260142.1	GalT	10..341	CDD:238341	158/349 (45%)
gal7	NP_596856.1	PRK11720	5..366	CDD:236963	165/365 (45%)
gal7	NP_596856.1	GalT	13..359	CDD:238341	158/349 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	173	1.000	Domainoid score	I877
eggNOG	1	0.900	-	-		E1_COG1085
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H126
Inparanoid	1	1.050	325	1.000	Inparanoid score	I538
OMA	1	1.010	-	-		QHG51955
OrthoFinder	1	1.000	-	-		FOG0004454
OrthoInspector	1	1.000	-	-		oto100811
orthoMCL	1	0.900	-	-		OOG6_101745
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R471
SonicParanoid	1	1.000	-	-		X3738
TreeFam	1	0.960	-	-
	13	12.760