Protein Alignment cup and eif4enif1

DIOPT Version :9

• Sequence 1: NP_001285687.1
• Gene: cup / 33934
• FlyBaseID: FBgn0000392
• Length: 1117
• Species: Drosophila melanogaster
• Sequence 2: XP_012821794.2
• Gene: eif4enif1 / 780398
• XenbaseID: XB-GENE-949044
• Length: 951
• Species: Xenopus tropicalis
• Alignment Length: 853
• Identity: 166/853 - (19%)
• Similarity: 272/853 - (31%)
• Gaps: 305/853 - (35%)

  Fly   448 LNHSK---------------WGYNDEDYHS--YHN-GKSQHMEEVNSKNSKNMTVLQ-------- 486
            |.|||               |  :.|.:||  |.| |:|..:|.:...:....|.|:
 Frog    39 LPHSKERPSCLLDKYDSDGVW--DPEKWHSSLYPNSGRSSPVEALKKDSDTERTSLKRRIADPRE 101

  Fly   487 --FFDNGEISSQPQRRP---NTPVMGMSINRSENDTLHSNESSEDLSRANENYVKRVMSGFLVVS 546
              ..|:.::...||||.   ...|:..:.:|.....| .|:.:|.:.....   :|:.||.::.:
 Frog   102 RVKEDDLDVVLSPQRRSFGGGCHVIAAASSRRSGSPL-DNKENESMRMLGS---RRIGSGRIMTA 162

  Fly   547 KPKSRDVE-DRHHR------------RYRNQN------------------EEPEWFSCGPTSRLD 580
            :...|||. ||..|            |:|.::                  |||||||.||||:.:
 Frog   163 RGFDRDVRGDREPREGRDREKEYKDKRFRREHGDSKRVFGERRRNDSCTEEEPEWFSGGPTSQSE 227

  Fly   581 TIELCGFDEDEEKMLKEGNKNHGLGETERETSKQKMDHKYKWTHAEPMGRSKYMPKHDTNNNHNV 645
            ||||.|||   :|:|:|.:|  |...|.:.|.|:.::                       .|..|
 Frog   228 TIELTGFD---DKILEEDHK--GRKRTRKRTGKEVIE-----------------------CNGGV 264

  Fly   646 ENMNNVMATEHQQQKE--------EKRPGSGRSFQFDKFNQSQQNYESSSYVNHQQPPQTQPQQM 702
            ......:..||...:|        |..||   .|.|::|    .|.:.|       .|.......
 Frog   265 LEEEVALPPEHAADQEVPEEAVLPEPAPG---EFDFNEF----FNLDKS-------VPGLASMIE 315

  Fly   703 QQQSNTNTNNSKFMSFFANEGNSS--SSSLN-------------EFFKQAINQGHGN-------- 744
            ......:.:.|:|..:|:|...|.  ||||.             |....|:.|..||
 Frog   316 DVLGEGSVSASRFSRWFSNHSRSGSRSSSLRSTPHEELERLAGLEQVIPALGQNSGNYFAPIQFE 380

  Fly   745 ----------------------------NPEQPKSLGHIGQMPSVDQLEAKWRRNSLNNVGETA- 780
                                        |.|:.:...|.|.:.||:::||.::...:...|:.|
 Frog   381 ERSDKVDILEILHKAKVDLKPLLSSLTANKEKLRERTHSGVVLSVEEVEAGFKGLKVEQEGKVAT 445

  Fly   781 --------------------NKQTD--NFQKLIGSLSSAKPQSQAVGYDAISNFIMQQQQYQQQQ 823
                                .|..|  .|.||:.|:.:             |..:..|.:..:.|
 Frog   446 PYMAEQLEEALTAMAGPRKIRKDGDMSAFNKLVSSMKA-------------SGTLPSQPKVNRNQ 497

  Fly   824 QKQHLIIQQQQQHTAFLASLQLKAILGR--ADTQLLLLRLTKGEISKHGLLVQLA-NPRL----- 880
              ...::......|..|....|:.:||:  .|:...:|....|.:....||.|.: :|::
 Frog   498 --DGAVLSSSNVATPPLQRNILQELLGQPIPDSSSHVLSNLMGTLDSASLLQQRSPSPQIPQVFP 560

  Fly   881 --------------------------------TDMDREAITAVLQFTNTQQQQQQHKQQLDMLSS 913
                                            |.:.:|....:.|.:..:.||    ..||....
 Frog   561 TRASSADYLRNRIPSPKGFPSGASQFLGEQFPTGLPKEEGPMMAQVSPLEMQQ----AALDGFIP 621

  Fly   914 TVIASQLQNLHN-------LAIVQQTLAARQQPQHN---------------PQTQAPHQLSQEDL 956
            |.||.|..|.::       :...::...:|.||:.|               |.......||..
 Frog   622 TDIALQAANYYHPGYGKMQMDKSREHFRSRPQPRVNKSPVANMRGASLSPGPGASVTSMLSPS-- 684

  Fly   957 QAHANVIMRNAVMKRKIEEQTSKLINGGAKHQAQQQYLNRGQQRQA----RPDANSNALLHALIS 1017
            ....:||.:....|.|.:::|....|.|.|.:..:. |..|....:    .|...|..:
 Frog   685 FTPTSVIRKMYESKEKSKDETVTKQNVGGKEEGHRT-LEDGSMPNSITHDSPQETSPVM------ 742

  Fly  1018 GGGNNHASGYPMNGQPQKHHSNLRFGDNQNFQSFESNQ-------PHFATQYKQQYQQ------- 1068
              ||..::....:..|...|.| |:..:|:::...:.:       |.....:.|...|
 Frog   743 --GNKVSTSQRSSCTPPLPHQN-RYTKDQDYRPKSTGRRTPTVASPVPGASFLQPLHQLPIVPVV 804

  Fly  1069 --SQQQHP 1074
              |.|.||
 Frog   805 RPSHQLHP 812

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cup	NP_001285687.1	DUF2477	227..>305	CDD:287586
eif4enif1	XP_012821794.2	EIF4E-T	28..700	CDD:371079	143/729 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006297
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12269
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.100