Protein Alignment CG11070 and Ube4a

DIOPT Version :9

• Sequence 1: NP_609060.1
• Gene: CG11070 / 33932
• FlyBaseID: FBgn0028467
• Length: 993
• Species: Drosophila melanogaster
• Sequence 2: XP_006243000.1
• Gene: Ube4a / 315608
• RGDID: 1303173
• Length: 1085
• Species: Rattus norvegicus
• Alignment Length: 1124
• Identity: 383/1124 - (34%)
• Similarity: 553/1124 - (49%)
• Gaps: 192/1124 - (17%)

  Fly     3 SIEENPFAALL---------------------------QEGA--NSDGVP--------------- 23
            :|..||||||.                           :|||  ||..||
  Rat     9 NISSNPFAALFGSLADAKQFAAIHKEQLKQQSGSVFGSEEGALCNSLHVPADELPASPDDSDNSV 73

  Fly    24 ------------------------------HKLVEEVLLFTLNKAS---------SSAVLCLADV 49
                                          :.:::.:.|.||:.:.         .|..:.|.::
  Rat    74 SESLDEFDYSVSEISRSFRTHQEMCEQLNINHMIQRIFLITLDNSDPNLKSGNGIPSRCVYLEEM 138

  Fly    50 VVE-TSEEMLSEDLVAHALFERLMLAETSQYAAG---------NASEMAMERRAMRYLKGAFTRC 104
            .|| ..::.|....|..|:|.||:|.:...:...         :|...|.||....||...|.|.
  Rat   139 AVELEDQDWLDMSNVEQAIFARLLLQDPGNHLISMTSSATLNLSADRDAGERHIFCYLYSCFQRA 203

  Fly   105 GLIQAERKIDCSKI-----------LALILNNASTCMRQPDLFAPQSFGAQWME-MFEQDEDEHD 157
                   |.:.:|:           ..|.::|..|.:..|:::..|:...|.:: |.|..:..|.
  Rat   204 -------KEEITKVPENLLPFAVQCRNLTVSNTRTVLLTPEIYVDQNIHEQLVDLMLEAIQGAHF 261

  Fly   158 TSTQEFLIRVTCKVMEEVEPIEAL------GALKAIFYPVLTELQKNIAKLNLITMKKNTFW-IL 215
            ....|||        |||  ||||      .....:..||...|...|..|.|..:....:. ||
  Rat   262 EDVTEFL--------EEV--IEALLLDEEVRTFPEVMIPVFDILLGRIKDLELCQILLYAYLDIL 316

  Fly   216 GYFVRDKRAAVLGELLIDYTTPNPRASGSEYMDTLLGSLLCISILPKTQ--TGKYEFF------- 271
            .||.|.|..|   ::.::|..|...::|..|..||||.:|.||.|.||.  ...:.||
  Rat   317 LYFTRQKDMA---KVFLEYIQPKDPSNGQMYQKTLLGVILNISCLLKTPGVVENHGFFLNPSRSS 378

  Fly   272 -QELSINQTDEALWALLSHHQQSIFLLVKQLLVLSPETKKKTLQWVGNCLDANVPRGHLWSSINA 335
             ||:.:.:.:  :...::...:.|:.::|.||.||||||...|.|:||||.||..|..:|:  |.
  Rat   379 PQEIKVQEAN--IHQFMAQFHEKIYQMLKNLLQLSPETKHGILFWLGNCLHANAGRTKIWA--NQ 439

  Fly   336 SLEQTAHSTSSDAFMTNLTAVLVRLCAPLCMP-SLKVLLVDPTYCAVP---NKDRQAKGVSMLRA 396
            ..|......:||||..||.|.|::||.|.|.| |.::|..:||||.:.   :::|:.|.|.|...
  Rat   440 MPEIFFQMYASDAFFLNLGAALLKLCQPFCKPRSSRLLTFNPTYCVLKDLNDEERKIKSVHMRGL 504

  Fly   397 HAETCLLTSEEGEERLTAEKYNFVTEIFYMTHKCFELSNIPCIERFVRVLRELQNTQMAYGEIVN 461
            ..||||:.:.  :|.:..:.||.|||...:|.....|......::.|::.:.|...|:|:.:...
  Rat   505 DKETCLIPAV--QEPVFPQSYNLVTENLALTEYTLYLGFHRLHDQMVKINQNLHRLQVAWRDAQQ 567

  Fly   462 SDPNSEVAKNLFRMIRDQIQQVLTI----KNTLAEPTNDMYLLKFFEASAIWLTEIAMLPREIYE 522
            |  :|..|.||    |:|.::::||    |..:.||......|....:.|:.|.::|
  Rat   568 S--SSPAADNL----REQFERLMTIYLSTKTAMTEPQMLQNCLNLQVSMAVLLVQLA-------- 618

  Fly   523 QCLDKRDFSPQVFRNMELLSDTPPFVAPYMQSVPESIIDNISAFLNAARKLNGEQYINIYFSAHD 587
              :......|     :||....|...:. :..|||...||:..||...|:. .|..:.....:.:
  Rat   619 --IGNEGSQP-----IELSFPLPDGYSS-LAYVPEFFADNLGDFLIFLRRF-AEDILETSADSLE 674

  Fly   588 AFFKMIILFMGSSALVKNPHLRAKLAEALEFLL------PSRIMGS--HRKTFVSHVFDNHPDRL 644
            .....|.:|.||...:|||||||||||.||.::      ||.::.|  |||    .||.|.|...
  Rat   675 HVLHFITIFTGSIERMKNPHLRAKLAEVLEAVMPHLDQTPSPLVSSVFHRK----RVFCNFPYAP 735

  Fly   645 KVVRSLLNVFVSIEMTGQSVQFEQKFNYRRPMYAIMEFLWTKPEHVQCFRDLAVEAEQNMDAIEP 709
            ::..:|:.|||.||.||...|||||||||||||.|:.::|....:.:..:|||..|.:|::|:.|
  Rat   736 QLSEALIKVFVDIEFTGDPHQFEQKFNYRRPMYPILRYMWGTDSYRESIKDLADYASKNLEAMNP 800

  Fly   710 PIFLRFINLLINDAIFLLDESLSNLEQIKQLQQAQDNGEWESLPHTEREQHMTNLQHLGMLARFD 774
            |:||||:|||:|||||||||::..|.:||..|..:|.||||||....|.:....||..|.||||.
  Rat   801 PLFLRFLNLLMNDAIFLLDEAIQYLSKIKIQQIEKDRGEWESLTPEARREKEAGLQMFGQLARFH 865

  Fly   775 NIIGRDTINLLKLLTSKIKSIFCHNSMVDRMAAMLNYFLLNLVGPKKERFKVKDKKEFEFDPAQT 839
            ||:..:||..|..|||:|||:|.|..:.:|:.:||||||.:|||||....||||..||:|.|.|.
  Rat   866 NIMSNETIGTLSFLTSEIKSLFVHPFLAERIISMLNYFLQHLVGPKMGALKVKDFSEFDFKPQQL 930

  Fly   840 VIEISHIYINLSSDESFCLAVSQDGRSYSEQLFSYAENILIRIG-GGQLIGDMSEFAVKVARMGA 903
            |.:|..||:||..:|:||..|.:||||||..||:....:|.:|. .|.:|...|..|.::..:..
  Rat   931 VSDICTIYLNLGDEENFCATVPKDGRSYSPTLFAQTVRVLKKINKPGNMIVAFSNLAERIKSLAD 995

  Fly   904 QYKEEQELLADAPEEYLDPIISTLMTDPVVLPSSKVTVDRSTIARHLLSDQTDPFNREPLTMDKV 968
            ..::|:|..|||.:|:||||:||||:||||||||:||||||||||||||||||||||.|||||::
  Rat   996 LQQQEEETYADACDEFLDPIMSTLMSDPVVLPSSRVTVDRSTIARHLLSDQTDPFNRSPLTMDQI 1060

  Fly   969 KSNEALKQEIESWIQGKRE 987
            :.|..||::|:.|:..:::
  Rat  1061 RPNTELKEKIQRWLAERKQ 1079

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11070	NP_609060.1	Ufd2P_core	251..898	CDD:287392	253/673 (38%)
		U-box	915..987	CDD:252675	50/71 (70%)
Ube4a	XP_006243000.1	UFD2	189..1080	CDD:227444	353/944 (37%)
		Ufd2P_core	349..990	CDD:287392	253/673 (38%)
		U-box	1007..1079	CDD:252675	50/71 (70%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341503
Domainoid	1	1.000	377	1.000	Domainoid score	I825
eggNOG	1	0.900	-	-		E1_COG5113
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3517
Inparanoid	1	1.050	525	1.000	Inparanoid score	I1200
OMA	1	1.010	-	-		QHG53881
OrthoDB	1	1.010	-	-		D194967at2759
OrthoFinder	1	1.000	-	-		FOG0006865
OrthoInspector	1	1.000	-	-		oto97154
orthoMCL	1	0.900	-	-		OOG6_108713
Panther	1	1.100	-	-	LDO	PTHR13931
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4960
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770