Protein Alignment CG11070 and ufd2

DIOPT Version :9

• Sequence 1: NP_609060.1
• Gene: CG11070 / 33932
• FlyBaseID: FBgn0028467
• Length: 993
• Species: Drosophila melanogaster
• Sequence 2: NP_593630.1
• Gene: ufd2 / 2542023
• PomBaseID: SPAC20H4.10
• Length: 1010
• Species: Schizosaccharomyces pombe
• Alignment Length: 1064
• Identity: 277/1064 - (26%)
• Similarity: 463/1064 - (43%)
• Gaps: 186/1064 - (17%)

  Fly     5 EENPFAALLQEGA------NSDGVPHKLVEEVLLFTLNKASSSAVLC---LADVVVETSEEMLSE 60
            |:...:..:..||      :.|...|.:..:.|..||::..||....   ..|:..|.|..:.:|
pombe    57 EQKEISPPVTSGAPKHRLFSKDEWMHFITCQALNITLSETDSSKYYLEGFKKDLEEEGSPLLFNE 121

  Fly    61 DLVAHALFERLMLAETSQYAAGNASEMAMERRAMRYLKGAFTRCGLIQAERKID----------- 114
            :.|..||..||.       ..||        ....||..:::  .|.|.::::.
pombe   122 NNVDSALLSRLS-------TTGN--------NTFSYLLQSWS--FLYQYKKRLPKDENQDFKIHY 169

  Fly   115 CSKILALILNNASTCMRQPDLF----------------APQSFGAQWMEMFEQDEDEHDTSTQEF 163
            .|.:.:|:::.|...:..||.|                .|..|.:::::.||.:.
pombe   170 LSLLKSLLVSYAGIVVMLPDTFNSETIDLAEVLIGAEGIPLEFLSEFVQRFEHEN---------- 224

  Fly   164 LIRVTCKVMEEVEPIEALGALKAIFYPVLTELQKNIAKLNLITMKKNTFWILGYFVRDKRAAVLG 228
                                |..:|.|||..|...|..:|:.|::.|...|:...|..|..|:|.
pombe   225 --------------------LDELFIPVLESLSLKIGLMNVDTVQMNVMQIILQLVSLKPIALLL 269

  Fly   229 ELLIDYTTPNPRASGSEYMDTLLGSLLCISILPKTQTGKYEFFQE------LSINQTDEALWALL 287
            ..|..: .|...|...|| .|.||.:..:|:.  ||.....:|..      .:|:.:..:|...:
pombe   270 PKLPSW-NPTNNAGEIEY-KTFLGRISSLSVF--TQDVASRYFSNSTERSAQNISSSISSLKLTM 330

  Fly   288 SHHQQSIFLLVKQLLVLSPETKKKTLQWVGNCLDANVPRGHLWSSINASLEQTAHSTSSDAFMTN 352
            |.:|..:|.:...|:..|...::..|.:....::||..|        .|::......:|||.|.|
pombe   331 STYQDVLFQIFNTLIRTSTSLRESVLDFFAMVVNANHKR--------QSIQVNHFDITSDACMLN 387

  Fly   353 LTAVLVRLCAP-LCMPSLKVLLVDPTYCAVPNKDRQAKGVSMLRAHAETCLLTSEEGEERLTAE- 415
            .:.||.||..| |.:...|:..|...|.      |:...|.:   ..||.|...::..|...::
pombe   388 FSHVLSRLSEPFLDIGCSKIDRVQVEYF------RRNPRVDI---KEETKLNADQKASESFYSKP 443

  Fly   416 ---KYNFVTEIFYMT---HKCFELSNIPCIERFVRVLRELQNTQMAYGEIVNSDPNSEVAKNLFR 474
               ..||:::||::.   |.....:....:|:.|:.:|:.:..:........:...|..|..|..
pombe   444 AEGSNNFISDIFFLNLAFHHYGVNATFKALEQLVQSIRDSEKLKERLETEQQNMSGSFQATRLTA 508

  Fly   475 MIRDQIQQVLTIKNT--------LAEPTNDMYLLKFFEASAIWLTEIAMLPREIYEQ---CLDKR 528
            .: .::.|.|.:..:        |.:.::......|....||||:.:|......|.:   .|...
pombe   509 QL-SRLDQRLDLDRSFVHCYEIMLTQTSDTSRSFSFLNFVAIWLSRLADGQSSTYPKMPLSLPFN 572

  Fly   529 DFSPQVFRNMELLSDTPPFVAPYMQSVPESIIDNISAFLNAARKLNGEQYINIYFSAHDAFFKMI 593
            :.:|:.|:                 .:||..|:.|:.::.:..|.:..   .:...:.:...:..
pombe   573 ENAPEAFK-----------------CLPEYFIETITDYMLSLFKTSSS---TLTLHSLEPLCEFC 617

  Fly   594 ILFMGSSALVKNPHLRAKLAEALEFLLPSRIMGSHRKTFVSHVFDNHPDRLKVVR---------- 648
            :.|:..:..:|||:|||||||.|.|.:.:.:..|..             .|.|||
pombe   618 VSFLTQANYIKNPYLRAKLAEILYFGVQTHVGRSEL-------------LLDVVRTSKVATRWLL 669

  Fly   649 -SLLNVFVSIEMTGQSVQFEQKFNYRRPMYAIMEFLWTKPEHVQCFRDLAVEAEQNMDAIEPPIF 712
             :|:..::.||.||||.||..|||.|..:..:...:|.:|.:   |..|..|.:.|:     |.|
pombe   670 PALMAFYIEIESTGQSTQFYDKFNIRFYICEVFRTIWKQPAY---FGKLEQEQKTNL-----PFF 726

  Fly   713 LRFINLLINDAIFLLDESLSNLEQIKQLQQAQDNGEWESLPHTEREQHMTNLQHLGMLARFDNII 777
            ::|:.|::|||.:||||:|..|.:|..||....:....|..:...::..:||......|.....:
pombe   727 VKFVALMLNDATYLLDEALLKLTEIHNLQSLLADAISNSNSNQNVQESQSNLAAAERQASTYCQL 791

  Fly   778 GRDTINLLKLLTSKIKSIFCHNSMVDRMAAMLNYFLLNLVGPKKERFKVKDKKEFEFDPAQTVIE 842
            |.:||.:|||.||.|...||...:|||:||||||.|..|.|||....||:|..::.|: |:|::.
pombe   792 GNETIFMLKLFTSSIPKAFCAVEIVDRLAAMLNYNLQALCGPKCSNLKVEDPTKYHFN-AKTLLS 855

  Fly   843 -ISHIYINLSSDESFCLAVSQDGRSYSEQLFSYAENILIR--IGGGQLIGDMSEFAVKVARMGAQ 904
             |..:|:||.::.:|..||:.||||||:::|..|.:|:.:  :.....|..:.||..:|.....|
pombe   856 IIFDVYLNLCNEPAFVEAVAHDGRSYSKEIFERATSIMTKHNLKSSFDIEAIKEFVNRVEAFRLQ 920

  Fly   905 YKEEQELLADAPEEYLDPIISTLMTDPVVLPSSKVTVDRSTIARHLLSDQTDPFNREPLTMDKVK 969
            ...|:|.:.|.|:.:|||::.|:|.||||||.|.:::|||||..|||||.||||||.|||:|.|.
pombe   921 EATEEEDMGDIPDYFLDPLMFTIMKDPVVLPRSGISIDRSTIKAHLLSDATDPFNRTPLTLDDVT 985

  Fly   970 SNEALKQEIESWIQGKREAARSNS 993
            .|:.|::||.::::.||.....||
pombe   986 PNDTLREEINTFLKSKRNKHSRNS 1009

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11070	NP_609060.1	Ufd2P_core	251..898	CDD:287392	174/685 (25%)
		U-box	915..987	CDD:252675	39/71 (55%)
ufd2	NP_593630.1	UFD2	76..1010	CDD:227444	274/1045 (26%)
		Ufd2P_core	290..914	CDD:287392	174/685 (25%)
		U-box	931..1003	CDD:252675	39/71 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	1.000	Domainoid score	I2053
eggNOG	1	0.900	-	-		E1_COG5113
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53881
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13931
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1598
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.950