Protein Alignment Oatp26F and Slco1a6

DIOPT Version :10

• Sequence 1: NP_609055.2
• Gene: Oatp26F / 33927
• FlyBaseID: FBgn0051634
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: XP_063142836.1
• Gene: Slco1a6 / 84608
• RGDID: 69304
• Length: 690
• Species: Rattus norvegicus
• Alignment Length: 672
• Identity: 192/672 - (28%)
• Similarity: 326/672 - (48%)
• Gaps: 77/672 - (11%)

  Fly    17 KCSNVNNNNSARSSRVGSSISGPDSDAECQRFGWCGWNPAWLQRFCTAKWALFWLCWGGALQGLI 81
            |.|....:::.:.:::|.    |:     :|.|..|     ::.|...|..|..|.|..|.:.|.
  Rat     6 KASKAETSSTNQKNKMGE----PE-----KRAGTHG-----IRCFAKIKVFLLALTWAYASKALS 56

  Fly    82 VNGLINVSISTIERRFGLRSRQMGLVASGYDLASFACLVPVTYYGGRRGASKPRFIAIGLIVMGM 146
            .. .:|..::.|||||.:.:..:||:...:::.:...::.|:|:|.:|  .:|..|.||..|||:
  Rat    57 AT-YMNSMLTQIERRFNISTSIVGLINGSFEVGNLLLIIFVSYFGRKR--HRPIMIGIGCAVMGL 118

  Fly   147 GSLVFLLPNFLVGNYRATIAEANVCETTGLPFNS-----NSSQSMTACELNAMGEGQSENLTWTV 206
            |..:..||:||:|.|.   .|..:..|:.|..||     |.:|::...:..|....:.::|.|.
  Rat   119 GCFIISLPHFLMGRYE---YETTISPTSNLSSNSFLCMENRTQTLKPTQDPAECVKEMKSLMWI- 179

  Fly   207 WLFLAAQLLHGAGASPLFTLGVTYIDENVSKKMSSVYLGIYYTMATVGPAIGYVFGGQLLLIYTD 271
             ..|...::.|.|.:|:..||::||::....:.|..|:||.......||......|.....||.|
  Rat   180 -YVLVGNIIRGIGETPIMPLGISYIEDFAKSENSPFYIGILEVGKITGPIAAIWLGSFCATIYVD 243

  Fly   272 WMTVDPVQLSLTSDSKVWIGAWWLGFIFAAAMCLLIALPIFGYPKLLP--GAEKLQLERVSEAHA 334
            ..:|:...|::|......:||||:||:..|.:.:||::|.|.:||..|  |.|.:       |:.
  Rat   244 MGSVNTDDLTITPTDTRCVGAWWIGFLVCAGLNILISIPFFFFPKTFPKEGPEDM-------ANE 301

  Fly   335 TISEADD-----SSNVVRGLPR----AVLSLLANPTFFFLNLAGATEGLVIAGFAA---FLPKQI 387
            |.::..|     :....||:.:    .:.||..||.:.   |...|..|.:.||.:   |.||.:
  Rat   302 TKNDEGDKHREKAKEEKRGITKDFFLFMKSLSCNPIYM---LCVLTSVLQVNGFVSIFTFKPKYL 363

  Fly   388 ENQFSISPMYSALVMGLITVPAGGGGTFLGGYLVKKWNLACR--GIIKMCLLATTVAALFTIC-F 449
            |:.:..|...:..:|||.|:|:...|..:.|:::||:.:..:  ..|..||..:  ..|.::| |
  Rat   364 EHHYGKSSSEAIFLMGLYTLPSVCVGYLISGFIMKKFKITLKKAAFISYCLGMS--ECLLSLCNF 426

  Fly   450 LVSCPNPKFAGVTTGYK-MQPSSD-SPALVASCNSNCGCSRTNYDPICGVDGVMYYSPCYAGCVQ 512
            :::|.|...||:||.|: :|.|.| ...::|.||:.|.|....:||:||.:|:.|.:||.|||.:
  Rat   427 MLTCDNVPIAGLTTSYEGIQQSFDMENTVLADCNTRCSCLTKTWDPVCGDNGLAYITPCLAGCEK 491

  Fly   513 EEHANSLKRYHNCSCIEQVGFVDDGNPSSEAP--HFRPDATNRKCDSTCQTLPLFVALCFILMVF 575
            ...:.......:||||:     ..||.|:...  :..||..|:        |..|:.:......|
  Rat   492 SVGSGINMVLQDCSCIQ-----SSGNSSAVLGLCNKGPDCANK--------LQYFLIITVFCSFF 543

  Fly   576 TFLATMPALSATLRCVQDDQRSFALGLQWIKVRLLGTIPAPLIFGALIDESCILW-QESCDKDAG 639
            ..|:.:|.....|||::.:::|..:|||...:|:||.|.||:.||.|||.:|:.| .:.|.:.
  Rat   544 YSLSLIPGYMIFLRCMKSEEKSLGIGLQAFCMRILGGILAPIYFGVLIDRTCLHWGTQKCGEP-- 606

  Fly   640 GACLVYD-NFYISRYMWLLALI 660
            |||..|: |.:.|.|:.|.|.:
  Rat   607 GACRTYEINSFRSIYLGLPAAL 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp26F	NP_609055.2	MFS_SLCO4_OATP4	64..589	CDD:340961	154/550 (28%)
Slco1a6	XP_063142836.1	None