Protein Alignment Oatp26F and Slco1a8

DIOPT Version :10

• Sequence 1: NP_609055.2
• Gene: Oatp26F / 33927
• FlyBaseID: FBgn0051634
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_001074787.1
• Gene: Slco1a8 / 625716
• MGIID: 3647159
• Length: 650
• Species: Mus musculus
• Alignment Length: 621
• Identity: 180/621 - (28%)
• Similarity: 298/621 - (47%)
• Gaps: 63/621 - (10%)

  Fly    68 LFWLCWGGALQGLIVNGLINVSIST-IERRFGLRSRQMGLVASGYDLASFACLVPVTYYGGRRGA 131
            |..|.|....:.|  :|...||:.| |||:|.:.:...||::..:.:.:...:|.|.|:|.:  .
Mouse     3 LMALTWAYVSKSL--SGTYMVSMLTQIERQFDIPASIAGLISGSFGIGNLLLIVFVNYFGMQ--L 63

  Fly   132 SKPRFIAIGLIVMGMGSLVFLLPNFLVGNYRATIAEANVCETTGLPFNS-----NSSQSM--TAC 189
            .:|..|.:|...||:|..:..||:||:|.|.   .|..:...:.||.||     |.||::  |..
Mouse    64 HRPIIIGVGCATMGLGCFLISLPHFLMGIYE---YETMISPASNLPSNSFLCVENRSQTLKPTQD 125

  Fly   190 ELNAMGEGQSENLTWTVWLF-LAAQLLHGAGASPLFTLGVTYIDENVSKKMSSVYLGIYYTMATV 253
            ....:.|.:|     ::|:: |...::.|.|.:||..|||:||::....:.|.:|:||..|....
Mouse   126 PAECVKEIKS-----SMWIYVLVGNIIRGIGETPLLPLGVSYIEDFAKSENSPLYIGILETGKMF 185

  Fly   254 GPAIGYVFGGQLLLIYTDWMTVDPVQLSLTSDSKVWIGAWWLGFIFAAAMCLLIALPIFGYPKLL 318
            ||.||.:.|.....||.|..:|:...|::|.....|:||||:||:..|.:.:|.::|.|.:||.|
Mouse   186 GPVIGLLLGSFCASIYVDTGSVNTDDLTITPTDTRWVGAWWIGFLVCAGVNVLTSIPFFFFPKTL 250

  Fly   319 PGAEKLQ-----LERVSEAHATISEADDSSNVVRGLPRAVLSLLANPTFFFLNLAGATEGLVIAG 378
            | .|.||     .|...|........:::..:.:.....:.||..:|.:....|...   |.|:.
Mouse   251 P-EEGLQDNGDGTENDKEEKHREKAKEENRGITKDFFPFMKSLSCDPIYVLFILISV---LQIST 311

  Fly   379 FAA---FLPKQIENQFSISPMYSALVMGLITVPAGGGGTFLGGYLVKKWNLACRGIIKMCLLATT 440
            |.:   ||.|.:|.||..|.......:||.|:|....|..:.|:::||:.:..:....:....:.
Mouse   312 FTSTFNFLSKYLEQQFGKSTAEVVFFIGLYTLPTICIGYLIAGFIMKKFKITVKKAAYLAFCLSL 376

  Fly   441 VAALFTIC-FLVSCPNPKFAGVTTGYK--MQPSSDSPALVASCNSNCGCSRTNYDPICGVDGVMY 502
            ...||..| ||::|.|...:|:|..|:  ..|......::|.||:.|.|....:||:||.:|:.:
Mouse   377 CEYLFGFCNFLIACDNVPVSGLTISYEGVQHPLYVENNVLADCNTRCSCLTKTWDPVCGDNGLSF 441

  Fly   503 YSPCYAGCVQEEHANSLKRYHNCSCIEQVGFVDDGNPSS------EAPHFRPDATNRKCDSTCQT 561
            .|.|:.||.:.........:.|||||.     ..|.||:      :.|         :|.:..|
Mouse   442 MSACHTGCEKSVGTGINMVFQNCSCIG-----SSGKPSAVLGLREKGP---------ECANKLQ- 491

  Fly   562 LPLFVALCFILMVFTFLATMPALSATLRCVQDDQRSFALGLQWIKVRLLGTIPAPLIFGALIDES 626
             .|.:...|:.::::..|| |..:..||||:.:::|..:|:.....|:.|.||||:..|||:|.:
Mouse   492 -HLLILSVFLSVIYSLSAT-PGYTVLLRCVESEEKSPGVGIHTFCTRVFGGIPAPVYIGALLDRT 554

  Fly   627 CILW-QESCDKDAGGACLVYD-NFYISRYMWLLALI 660
            |:.| .:.|.:.  |||.:|| |.:.|.|:.|.|.:
Mouse   555 CLHWGTQKCGEP--GACRMYDINSFRSIYLGLPAAL 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp26F	NP_609055.2	MFS_SLCO4_OATP4	64..589	CDD:340961	151/546 (28%)
Slco1a8	NP_001074787.1	oat	1..605	CDD:273279	180/621 (29%)