Protein Alignment Oatp26F and slco1b3

DIOPT Version :10

• Sequence 1: NP_609055.2
• Gene: Oatp26F / 33927
• FlyBaseID: FBgn0051634
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: XP_031753845.1
• Gene: slco1b3 / 613085
• XenbaseID: XB-GENE-5943217
• Length: 690
• Species: Xenopus tropicalis
• Alignment Length: 727
• Identity: 204/727 - (28%)
• Similarity: 327/727 - (44%)
• Gaps: 105/727 - (14%)

  Fly    12 IAVAPKCSNVNNNNSARSSRVGSSISG--PDSDAECQRFGWCGWNPAWLQRFCTAKWALFWLCWG 74
            :.|..:.|:.||.|......:.|:..|  |.....|     |.....:|...|.:.:|
 Frog     1 MTVEKEPSDSNNPNMDPPEVLMSNGGGETPPQKVSC-----CSNLKMFLVALCFSYFA------- 53

  Fly    75 GALQGLIVNGLINVSISTIERRFGLRSRQMGLVASGYDLASFACLVPVTYYGGRRGASKPRFIAI 139
            .|..|    ..:..||:.|||||.:.|..:|::...:::.:...:..|:|:|.:  ..:||.||.
 Frog    54 KAFSG----SYMKSSITQIERRFDISSSTVGMIDGSFEIGNLMVIAIVSYFGAQ--FHRPRIIAA 112

  Fly   140 GLIVMGMGSLVFLLPNFLVGNYRATIAEANVCETTGLP--FNSNSSQSMTACELN---------- 192
            |.|:|.:||.:..:|:|.:|.|:        .||.|.|  .|||::.:::.|..|
 Frog   113 GCILMSLGSFLTAMPHFFMGLYK--------YETVGGPTSLNSNATINVSPCLANRSLVDTPKPD 169

  Fly   193 AMGEGQSENLTWTVWLF-LAAQLLHGAGASPLFTLGVTYIDENVSKKMSSVYLGIYYTMATVGPA 256
            .:.|..|.     :|:| |...:|.|.|.:|:..||::|:|:....:.:.:::...:|:|..||.
 Frog   170 CVTENGSH-----MWVFLLVGNILRGIGETPIAPLGISYLDDFSRPENTPLHIACLHTVAMFGPM 229

  Fly   257 IGYVFGGQLLLIYTDWMTVDPVQLSLTSDSKVWIGAWWLGFIFAAAMCLLIALPIFGYPKLLPGA 321
            .|::.|..|..:|.|...||...:::|.....|:||||:||:.:.|:.|:.|:|.|..|
 Frog   230 TGFMLGSFLARLYVDIGFVDTDTITITPQDTRWVGAWWIGFLLSGAVNLMSAIPFFFLP------ 288

  Fly   322 EKLQLERVSEAHATISEADDSSN------VVRGLPRAVLSLLANPTFFFLNLAGATEGLVIAGFA 380
            |.|:.|:.........:.::..:      .:||...|:.:|..|..|..|......:.....||.
 Frog   289 ESLKEEQREGQKPQTKQGEEKGHKQKEKPTLRGFFAALKTLCFNRLFVMLMCLTLLQTNSFLGFI 353

  Fly   381 AFLPKQIENQFSISPMYSALVMGLITVPAGGGGTFLGGYLVKKWNLACRGIIKMCLLATTVAALF 445
            .:.||.:|.|:..|...:..|.|:.|:||...|.||||.::|::.....|..||....:.:|.|.
 Frog   354 TYKPKYMEQQYGQSISKANFVTGVSTLPAAALGMFLGGLIMKRYKFGLLGASKMAYGTSLLAFLL 418

  Fly   446 TI-CFLVSCPNPKFAGVTTGY---KMQPSSDSPALVASCNSNCGCSRTNYDPICGVDGVMYYSPC 506
            :: .|.:.|.|...||:|..|   |:....|. .:.:.|||:|.||...:||:||.:||.|.|.|
 Frog   419 SLSAFFIGCENNNVAGITVTYDRVKVNNFQDR-IIYSPCNSDCHCSSKQWDPVCGENGVTYVSAC 482

  Fly   507 YAGCVQEEHANSLKRYHNCSCIEQV--GFVDDGNPSSEAPHFRPDATNRKCDSTCQTLPLFVALC 569
            .|||.....:.....|||||||:..  ..|:........|. .||         |..:.:|..:.
 Frog   483 LAGCKASTGSGLGTVYHNCSCIDTALSTAVNSSAHLGSCPR-GPD---------CSRMFMFYVVT 537

  Fly   570 FILMVFTF-LATMPALSATLRCVQDDQRSFALGLQWIKVRLLGTIPAPLIFGALIDESCILW-QE 632
            ..:..|.| |....|....|..|..:.:|.|:|:..:.:|.|..||||:.|||:||:||:.| ..
 Frog   538 QAINTFIFALGASSAYVLLLWSVNPEMKSLAVGVYMLLIRTLAGIPAPIYFGAIIDKSCLKWGTR 602

  Fly   633 SCDKDAGGACLVYD-NFYISRYMWLLALICKLGSVVFFACAWWFYV-----PPS----------- 680
            .|  ...|||.:|| :.:..|::.|.|.|.....::||.    |.|     ||:
 Frog   603 LC--GGRGACRLYDADSFRRRFLGLTAGIRAPSYILFFI----FIVMVKRRPPTGTGAPQPHEKA 661

  Fly   681 -----KPLNANG 687
                 |.|.|||
 Frog   662 ENCDKKELYANG 673

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp26F	NP_609055.2	MFS_SLCO4_OATP4	64..589	CDD:340961	152/550 (28%)
slco1b3	XP_031753845.1	MFS_SLCO1B_OATP1B	40..558	CDD:341015	154/560 (28%)