Protein Alignment Oatp26F and Slco1c1

DIOPT Version :10

• Sequence 1: NP_609055.2
• Gene: Oatp26F / 33927
• FlyBaseID: FBgn0051634
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_067446.1
• Gene: Slco1c1 / 58807
• MGIID: 1889679
• Length: 715
• Species: Mus musculus
• Alignment Length: 692
• Identity: 204/692 - (29%)
• Similarity: 331/692 - (47%)
• Gaps: 78/692 - (11%)

  Fly    23 NNNSARSSRVGSSISGPDSDAECQRFGWCGWNPAWLQRFCTAKWALFWLCWGGALQGL-----IV 82
            :.|||:.:...|...|..|..|.              |.|..|..:|.    |||..:     :.
Mouse    13 HKNSAQPAGGPSFTVGYPSTEEA--------------RPCCGKLKVFL----GALSFVYFAKALA 59

  Fly    83 NGLINVSISTIERRFGLRSRQMGLVASGYDLASFACLVPVTYYGGRRGASKPRFIAIGLIVMGMG 147
            .|.:..:::.|||||.:.|..:|::...:::.:...:..|:|:|.:  ..:|:.|..|.:|||.|
Mouse    60 EGYLKSTVTQIERRFEIPSSLVGIIDGSFEIGNLLVITFVSYFGAK--LHRPKIIGAGCLVMGFG 122

  Fly   148 SLVFLLPNFLVGNYRATIAE-----ANVCETTG---LPFNSNSSQSMTACELNAMGE---GQSEN 201
            :::..:|.|.:..|.....|     :||..:..   |..:|.|..|:.....|.:..   |.|.:
Mouse   123 TMLIAVPQFFMEKYSYEKYERYSPSSNVTPSISPCYLESSSPSPSSILGKSQNKISHECVGDSSS 187

  Fly   202 LTWTVWLFLAAQLLHGAGASPLFTLGVTYIDENVSKKMSSVYLGIYYTMATVGPAIGYVFGGQLL 266
            ..| |::|| ..||.|.|.:|:..||:.|:|:..|:..::.|:|...|:|.:||..|::.|....
Mouse   188 SMW-VYVFL-GNLLRGLGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCA 250

  Fly   267 LIYTDWMTVDPVQLSLTSDSKVWIGAWWLGFIFAAAMCLLIALPIFGYPKLLPGAEKLQLE-RVS 330
            .:|.|...|:...:::|.....|:||||||::.|..:.||.|:|.:..||.||.::..:.. ..|
Mouse   251 KLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGFLSLLAAVPFWCLPKTLPRSQSRENSGSTS 315

  Fly   331 E--------AHATISEADDSSNVVR----GLPRAVLSLLANPTFFFLNLAGATEGLVIAGFAAFL 383
            |        .|..::..||...::.    .|| ::.:|..||.:.....|...:...:.|...:.
Mouse   316 EKSKFIDDPIHYQMAPGDDKMKIMEMAKDFLP-SLKTLFRNPVYILYLCASTVQFNSLFGMVTYK 379

  Fly   384 PKQIENQFSISPMYSALVMGLITVPAGGGGTFLGGYLVKKWNLACRGIIKMCLLATTVA-ALFTI 447
            ||.||.|:..|...:..|:|||.:||...|.|.||.::||:.|......|:.|.::... .||..
Mouse   380 PKYIEQQYGQSSSKANFVIGLINIPAVALGIFSGGIVMKKFRLGICEATKLYLGSSVFGYLLFLS 444

  Fly   448 CFLVSCPNPKFAGVTTGYK-MQP-SSDSPALVASCNSNCGCSRTNYDPICGVDGVMYYSPCYAGC 510
            .|.:.|.|...||:|..|: .:| |....||.:.|||.|.||.:.::|:||.:|:.|.|.|.|||
Mouse   445 LFALGCENSSVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSDSKWEPMCGDNGITYVSACLAGC 509

  Fly   511 VQEEHANSLKRYHNCSCIEQVGFV--DDGNPSSEAPHFRPDATNRKC--DSTCQTLPLFVALCFI 571
            .....:.....:.||:|   |||.  ..||.|         ....:|  |:.|..:.|:..:..:
Mouse   510 QSSSRSGKNIIFSNCTC---VGFAAPKSGNWS---------GMMGRCQKDNGCSQMFLYFLVISV 562

  Fly   572 LMVFTF-LATMPALSATLRCVQDDQRSFALGLQWIKVRLLGTIPAPLIFGALIDESCILWQ-ESC 634
            :..:|. |..:|.....|||:|...:|||||:..:.||:|..||||:.||.|||.||:.|. :.|
Mouse   563 ITSYTLSLGGIPGYILLLRCIQPQLKSFALGIYTLAVRVLAGIPAPVYFGVLIDTSCLKWGFKKC 627

  Fly   635 DKDAGGACLVYDNFYISRYMWLLALICKLGSV-VFFACAWWF 675
              .:.|:|.:||: :..|::: |.|...||:| ||.:.|..|
Mouse   628 --GSRGSCRLYDS-HAFRHIY-LGLTTLLGTVSVFLSMAVLF 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp26F	NP_609055.2	MFS_SLCO4_OATP4	64..589	CDD:340961	156/561 (28%)
Slco1c1	NP_067446.1	MFS	42..582	CDD:475125	156/560 (28%)