Protein Alignment Oatp26F and Slco1a1

DIOPT Version :10

• Sequence 1: NP_609055.2
• Gene: Oatp26F / 33927
• FlyBaseID: FBgn0051634
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_058807.1
• Gene: Slco1a1 / 50572
• RGDID: 3700
• Length: 670
• Species: Rattus norvegicus
• Alignment Length: 629
• Identity: 183/629 - (29%)
• Similarity: 307/629 - (48%)
• Gaps: 61/629 - (9%)

  Fly    64 AKWALFWL-----CWGGALQGLIVNGLINVSISTIERRFGLRSRQMGLVASGYDLASFACLVPVT 123
            :|..:|.|     |...:|.|:.:|.:    ::.|||:|.:.:...||:...:::.:...:|.|:
  Rat    17 SKMKVFLLSLTCACLTKSLSGVYMNSM----LTQIERQFDISTSVAGLINGSFEIGNLFFIVFVS 77

  Fly   124 YYGGRRGASKPRFIAIGLIVMGMGSLVFLLPNFLVGNYRATIAEANVCETTGLPFNS-----NSS 183
            |:|.:  ..:|..|.||.::||:|.|:..||:|.:|.|.   .|..:..|..|..||     |.:
  Rat    78 YFGTK--LHRPVVIGIGCVIMGLGCLLMSLPHFFMGRYE---YETTISPTGNLSSNSFLCMENRT 137

  Fly   184 QSMTACELNAMGEGQSENLTWTVWLFLAAQLLHGAGASPLFTLGVTYIDENVSKKMSSVYLGIYY 248
            |::...:..|....:.::|.|.  ..:...::.|.|.:|:..||::||::....:.|.:|:||..
  Rat   138 QTLKPTQDPAECVKEMKSLMWI--CVMVGNIIRGIGETPIVPLGISYIEDFAKSENSPLYIGILE 200

  Fly   249 TMATVGPAIGYVFGGQLLLIYTDWMTVDPVQLSLTSDSKVWIGAWWLGFIFAAAMCLLIALPIFG 313
            .....||..|.:.|.....||.|..:|:...|::|.....|:||||:||:..|.:.:|.::|.|.
  Rat   201 MGKVAGPIFGLLLGSYCAQIYVDIGSVNTDDLTITPSDTRWVGAWWIGFLVCAGVNILTSIPFFF 265

  Fly   314 YPKLLPGAEKLQLERVSEAHATISE------ADDSSNVVRGLPRAVLSLLANPTFFFLNLAGATE 372
            .||.||  :|.|.|.|:.......|      .:::..:.:.....:..|..||.:....|   |.
  Rat   266 LPKALP--KKGQQENVAVTKDGKVEKYGGQAREENLGITKDFLTFMKRLFCNPIYMLFIL---TS 325

  Fly   373 GLVIAGFA---AFLPKQIENQFSISPMYSALVMGLITVPAGGGGTFLGGYLVKKWNLACRGIIKM 434
            .|.:.||.   .||||.:|.|:..|...:..::|:.::|....|..:||:::||:.:..:....:
  Rat   326 VLQVNGFINKFTFLPKYLEQQYGKSTAEAIFLIGVYSLPPICLGYLIGGFIMKKFKITVKKAAYL 390

  Fly   435 CLLATTVAALFTIC-FLVSCPNPKFAGVTTGYK---MQPSSDSPALVASCNSNCGCSRTNYDPIC 495
            ....:....|..:| |:::|.|...||:||.||   .|...:|..| |.||:.|.||...:||:|
  Rat   391 AFCLSVFEYLLFLCHFMLTCDNAAVAGLTTSYKGVQHQLHVESKVL-ADCNTRCSCSTNTWDPVC 454

  Fly   496 GVDGVMYYSPCYAGCVQEEHANSLKRYHNCSCIEQVGFVDDGNPSSEAPHFR--PDATNRKCDST 558
            |.:||.|.|.|.|||.:.....:...:.:||||:.:     ||.|:.....:  |:..||
  Rat   455 GDNGVAYMSACLAGCKKFVGTGTNMVFQDCSCIQSL-----GNSSAVLGLCKKGPECANR----- 509

  Fly   559 CQTLPLFVALCFILMVFTFLATMPALSATLRCVQDDQRSFALGLQWIKVRLLGTIPAPLIFGALI 623
               |..|:.|..|:.....|..:|.....||||:.:::|..:||....:|:...||||:.|||||
  Rat   510 ---LQYFLILTIIISFIYSLTAIPGYMVFLRCVKSEEKSLGVGLHTFCIRVFAGIPAPVYFGALI 571

  Fly   624 DESCILWQE-SCDKDAGGACLVYD-NFYISRYMWLLALICKLGS 665
            |.:|:.|.. .|.:  .|||.:|| |.:  |:::|...|...||
  Rat   572 DRTCLHWGTLKCGQ--RGACRMYDINSF--RHIYLGLPIALRGS 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp26F	NP_609055.2	MFS_SLCO4_OATP4	64..589	CDD:340961	151/549 (28%)
Slco1a1	NP_058807.1	oat	1..625	CDD:273279	183/629 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	645..670