Protein Alignment Oatp26F and Slco4c1

DIOPT Version :10

• Sequence 1: NP_609055.2
• Gene: Oatp26F / 33927
• FlyBaseID: FBgn0051634
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_001002024.2
• Gene: Slco4c1 / 432363
• RGDID: 1303048
• Length: 724
• Species: Rattus norvegicus
• Alignment Length: 703
• Identity: 267/703 - (37%)
• Similarity: 383/703 - (54%)
• Gaps: 60/703 - (8%)

  Fly     2 SEATIELDSSIAVAPKCSNVNNNNSAR--------------SSRVGSSISGPDSDAECQRFGWCG 52
            |.:.:|:.   |||.:  |.|..:..|              ||.:.:|...|.|.......|.||
  Rat    26 SPSQVEVS---AVASR--NQNGGSQPRESEDPQKSTEPSPPSSTLPASDEPPGSQLSELEEGPCG 85

  Fly    53 W---NPAWLQRFCTAKWALFWLCWGGALQGLIVNGLINVSISTIERRFGLRSRQMGLVASGYDLA 114
            |   :|..|||....|..|...|.....||::||||:|:||||||:|:.::|...||::|.||:
  Rat    86 WRNFHPQCLQRCNNPKGFLLHYCLLALTQGIVVNGLVNISISTIEKRYEMKSSLTGLISSSYDI- 149

  Fly   115 SFACLVPVTYYGGRRGASKPRFIAIGLIVMGMGSLVFLLPNFLVGNYRATIAEANVCETTGLPFN 179
            ||..|.....:.|.|| .|||::|....::|:|:|||.||:|..|.|..    ..:.|.|.|..|
  Rat   150 SFCVLSLFVSFFGERG-HKPRWLAFASFMIGLGALVFSLPHFFSGRYEL----GTIFEDTCLTRN 209

  Fly   180 SNSSQSMTACELNAMGEGQSENLTWTVWLFLAAQLLHGAGASPLFTLGVTYIDENVSKKMSSVYL 244
            |....|.|:...|..            ::|:..|||.|.|.:||:|||..:||::|....||:|:
  Rat   210 STRCASSTSLLSNYF------------YVFVLGQLLLGTGGTPLYTLGTAFIDDSVPTHKSSLYI 262

  Fly   245 GIYYTMATVGPAIGYVFGGQLLLIYTDWMTVDPVQLS-LTSDSKVWIGAWWLGFIFAAAMCLLIA 308
            ||.|:|:.:|||||||.|||||.:|.|   |...|.| ||.|...|:||||:||:.|......:.
  Rat   263 GIGYSMSILGPAIGYVLGGQLLTMYID---VAMGQSSDLTEDDPRWLGAWWIGFLLAWLFAWSLI 324

  Fly   309 LPIFGYPKLLPGAEKLQLERVSEAHATISEA-----DDSSNVVRGLPRAVLSLLANPTFFFLNLA 368
            :|...:||.|||..|:|..:.|:.|...|.:     ::....::..|.||.:|:.|..|..|.|:
  Rat   325 MPFSCFPKHLPGTAKIQAGKTSQTHQNNSTSFQHMDENFGKSIKDFPTAVKNLMRNTVFICLVLS 389

  Fly   369 GATEGLVIAGFAAFLPKQIENQFSISPMYSALVMGLITVPAGGGGTFLGGYLVKKWNLACRGIIK 433
            ..:|.||..|||.||||.|||||.::..::|.:.|.:.:|....|..|||.||.|:.:.|:..:|
  Rat   390 TTSEALVTTGFATFLPKFIENQFGLTSSFAATLGGAVLIPGAALGQILGGVLVSKFKMKCKNTMK 454

  Fly   434 MCLLATTVAALFTICFL-VSCPNPKFAGVTTGYKMQPSSDSPALVASCNSNCGCSRTNYDPICGV 497
            ..|..:.||.:.:..|: ..|.|..||||:..|  ..:.:...|.|.||:||.|.|:.|.|:||.
  Rat   455 FALCTSGVALMLSFVFIYAKCENGPFAGVSESY--NGTGEMGNLTAPCNANCNCLRSYYYPLCGS 517

  Fly   498 DGVMYYSPCYAGCVQEEHANSLKRYHNCSCIEQVGFVDDGNPSSEAPHFRPDATNRKCDSTCQTL 562
            |||.|:|||:|||:........|.|:||||||:   ..|...::|:|.|  :|...||.:.|..|
  Rat   518 DGVQYFSPCFAGCLNSVSNRKPKAYYNCSCIER---KVDITSTAESPDF--EARAGKCKTQCSNL 577

  Fly   563 PLFVALCFILMVFTFLATMPALSATLRCVQDDQRSFALGLQWIKVRLLGTIPAPLIFGALIDESC 627
            |:|:.:.||.::|||:|..|...:.||||...|||.|||:|::.:|||||||.|:|||..||.:|
  Rat   578 PIFLGIFFITVIFTFMAGTPITVSILRCVNHRQRSLALGVQFMLLRLLGTIPGPIIFGVTIDSTC 642

  Fly   628 ILWQ-ESCDKDAGGACLVYDNFYISRYMWLLALICKLGSVVFFACAWWFYVPP 679
            :||. ..|  ...|||.:|||..::..:..:::.||:.::.|...|...|.||
  Rat   643 VLWDINEC--GTKGACWIYDNIRMAHMLVAISVTCKVITIFFNGLAIVLYKPP 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp26F	NP_609055.2	MFS_SLCO4_OATP4	64..589	CDD:340961	205/531 (39%)
Slco4c1	NP_001002024.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..80		13/58 (22%)
		MFS_SLCO4C_OATP4C	100..604	CDD:341021	205/531 (39%)