Protein Alignment Oatp26F and Oatp74D

DIOPT Version :10

• Sequence 1: NP_609055.2
• Gene: Oatp26F / 33927
• FlyBaseID: FBgn0051634
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_648989.1
• Gene: Oatp74D / 39954
• FlyBaseID: FBgn0036732
• Length: 819
• Species: Drosophila melanogaster
• Alignment Length: 726
• Identity: 196/726 - (26%)
• Similarity: 321/726 - (44%)
• Gaps: 124/726 - (17%)

  Fly    19 SNVNNNNSARSSRVGSSISGPDSDAECQRFGWCGWNPAWLQRFCTAK--WALFWLCWGGALQGLI 81
            |::|..:||.||            :.|..|| |  .|.|.:||.:..  ..:|.|.:  .|||:.
  Fly   143 SDLNGGSSAESS------------SSCGLFG-C--RPRWARRFASTHVFMVVFLLAY--ILQGMY 190

  Fly    82 VNGLINVSISTIERRFGLRSRQMGLVASGYDLASFACLVPVTYYGGRRGASKPRFIAIGLIVMGM 146
            :...::| |:|||:.|.::|:..|::.|..::......:.:||:.||  ..:||:||.|:::..:
  Fly   191 MTYFVSV-ITTIEKLFQIKSKTTGILLSASEMGQICTAMLLTYFAGR--GHRPRWIACGMVLFSI 252

  Fly   147 GSLVFLLPNFLVG---------------------------NYRATIAEANVCETTGLPFNSNSSQ 184
            .:....||:|:.|                           |..:.....|:|...|     |.:.
  Fly   253 AAFSCALPHFIFGEQLMHSSVILQQTQVSPPNNSFSSHWLNASSEQVNPNLCILGG-----NQTH 312

  Fly   185 SMTAC-ELNAMGEGQSENLTWTV-WLFLAAQLLHGAGASPLFTLGVTYIDENVSKKMSSVYLGIY 247
            |.:.| |...:.:.....:|..| .:|..:.|..|.|.:.:.|||:.|||:||..|.|.:|:.:.
  Fly   313 SGSECNEERQLEQASHSKITVIVLCIFFGSLLSSGIGQTAVATLGIPYIDDNVGSKQSPMYMAVT 377

  Fly   248 YTMATVGPAIGYVFGGQLLLIYTDWM-----TVDPVQLSLTSDSKVWIGAWWLGFIFAAAMCLLI 307
            ..|..:|||.|::||......|.::.     ..||          .||||||||.:...::.||.
  Fly   378 IGMRILGPASGFIFGSFCTRWYVNFSNPGFDATDP----------RWIGAWWLGPVAIGSLMLLA 432

  Fly   308 ALPIFGYPKLLPGAEKLQLERVSEAHATISEADDSSNVVRGLPRAVLSLLANPTFFFLNLAGATE 372
            ::.:|.:||.|.|.:|...:..:.|.....|....   ::..|:.|...|:|....|...:....
  Fly   433 SIAMFSFPKQLRGKQKPPGQTATPAAPVEPEEKPK---LKDFPKTVRRQLSNDILMFRTASCVFH 494

  Fly   373 GLVIAGFAAFLPKQIENQFSISPMYSALVMGLITVPAGGGGTFLGGYLVKKWNLACRGIIK-MCL 436
            .|.|||...||||.:|.||.::...:.::.....:...|.|..:.|..:.|.....||:.. :..
  Fly   495 LLPIAGLYTFLPKYLETQFRLATYDANMIAAFCGILVMGIGIVISGLFILKRKPTARGVAAWIAF 559

  Fly   437 LATTVAALFTICFLVSCPNPKFAGVTTGYKMQPS-SDSPALV-ASCNS--NCGCSRTNYDPICGV 497
            .|...:|...|...:.|....||    |||  || .:||||: .:|::  ||.|.:.|:.||| .
  Fly   560 TALVYSAGMIILMFIGCSMNDFA----GYK--PSDGNSPALIEPTCSAALNCTCDKENFAPIC-A 617

  Fly   498 DGVMYYSPCYAGCVQEEHANSLKR--YHNCSCIEQVGFVDDGNPSSEAPHFRPDATNRKCDSTCQ 560
            ||.||.|.|:|||.......|..|  |.:|:||...                |:|.|..||:.|:
  Fly   618 DGKMYISACHAGCSSSSLRPSDNRTLYSDCACIPDA----------------PEAVNGYCDNNCK 666

  Fly   561 TLPLFVALCFILMVFTF-LATMPALSATLRCVQDDQRSFALGLQWIKVRLLGTIPAPLIFGALID 624
            ....|: |.|.:.||.. .:.:.::...:||.....::.|:|:....:.|.|.:|.|:|:||::|
  Fly   667 NFIYFI-LIFAICVFMHSTSEVGSMLLVMRCTHPKDKAMAMGVIQSAIGLFGNVPCPIIYGAVVD 730

  Fly   625 ESCILWQESCDKDAGGACLVYDNFYISRY--------MWLLALICKLGSVVFFACAWWFYVPPSK 681
            .:|::|:..|.|.  |||.:||.....:|        |:|..|:    .:|.:..|....:.|..
  Fly   731 SACLIWKSVCGKH--GACSLYDADTFRQYFLGITAGIMFLAFLM----DLVVWRKAHRIDIAPED 789

  Fly   682 PLN----ANGK 688
            |..    :||:
  Fly   790 PQEGGPASNGR 800

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp26F	NP_609055.2	MFS_SLCO4_OATP4	64..589	CDD:340961	151/568 (27%)
Oatp74D	NP_648989.1	OATP	175..754	CDD:460821	172/627 (27%)