Protein Alignment Oatp26F and Slco6d1

DIOPT Version :10

• Sequence 1: NP_609055.2
• Gene: Oatp26F / 33927
• FlyBaseID: FBgn0051634
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: XP_017452073.1
• Gene: Slco6d1 / 367321
• RGDID: 1359388
• Length: 723
• Species: Rattus norvegicus
• Alignment Length: 609
• Identity: 169/609 - (27%)
• Similarity: 273/609 - (44%)
• Gaps: 65/609 - (10%)

  Fly    58 LQRFCTAKWALFWLCWGGALQGLIVNGLINVSISTIERRFGLRSRQMGLVASGYDLASFACLVPV 122
            ||||......|.....|....|:|. ||::.|:............:...:.||.|||:|...:..
  Rat    78 LQRFNNINCFLTAYFLGTMAHGMIF-GLVDQSLKVYVSELSPSKLETLTMGSGDDLAAFLVSLVG 141

  Fly   123 TYYGGRRGASKPRFIAIGLIVMGMGSLVFLLPNFLVGNYR----ATIAE---------ANVCETT 174
            .::|||  .::.|::.....|.|:.|:||.:|.|   ||.    .|:.:         ..|||.|
  Rat   142 AHFGGR--GNRVRWMVAACFVTGLASMVFAIPFF---NYEIIKLGTVTDELCIEGKKTTKVCERT 201

  Fly   175 GLPFNSNSSQSMTACELNAMGEGQSENLTWTVWLFLAAQLLHGAGASPLFTLGVTYIDENVSKKM 239
            .:|..|       .|                :..|...|.|||....|.:.|..::|.::|....
  Rat   202 VIPHKS-------TC----------------IAFFNFGQFLHGIAGMPFYLLAFSFIFDHVPTCS 243

  Fly   240 SSVYLGIYYTMATVGPAIGYVFG--GQLLLIYTDWMTVDPVQLSLTSDSKVWIGAWWLGFIFAAA 302
            |.:||.|..|..:||..:||:.|  .::..:..|...|..||     ..::....||..:...|.
  Rat   244 SGLYLAIADTALSVGYVLGYLVGIRNRMFPVKEDMKAVGHVQ-----QFRILQRNWWRSYFAVAV 303

  Fly   303 MCLLIALPIFGYPKLLPGAEKLQLERVSEAHATISEADDSSNV---VRGLPRAVLSLLANPTFFF 364
            ......||:..:|..|.||::::||: |:...||........:   ::|:..|:..||.||....
  Rat   304 FAFCTTLPLSCFPSRLRGAQQIRLEK-SKEPPTIDRRLKDKEIQPGLKGVLHAIWCLLRNPLVLT 367

  Fly   365 LNLAGATEGLVIAGFAAFLPKQIENQFSISPMYSALVMGLITVPAGGGGTFLGGYLVKKWNLACR 429
            ......|:.|.:.....||||.:::.|.|.|..::::.|:..:|....|.|||||:|.:..::.:
  Rat   368 QTFCQVTKSLTLKSSGYFLPKFLQSHFLIVPTNASILTGMFVLPGALIGRFLGGYIVDRLQMSTK 432

  Fly   430 GIIKMCLLATTVA-ALFTICFLVSCPNPKFAGVTTGYKMQPSSDSPALVASCNSNCGCSRTNYDP 493
            .::|..::::.:: .||.:.|..||....|||:...|.......:  ..|.||..|||:.|:|..
  Rat   433 VVLKFMMVSSFISVVLFLLTFFWSCETAGFAGINDDYDGLGKLGN--FTAPCNEYCGCTMTDYST 495

  Fly   494 ICGVDGVMYYSPCYAGCVQEEHANSLKRYHNCSCIEQVGFVDDGNPSSEAPHFRPDATNRKCDST 558
            |||.|...|:|.|:|||...:.....|.|:|||||:: |..   .|..:...|  ||.:..|::.
  Rat   496 ICGRDEKQYFSACFAGCRASKPLRKEKAYYNCSCIKE-GLT---APDDDGQFF--DAVSGTCNTK 554

  Fly   559 CQTLPLFVALCFILMVFTFLATMPALSATLRCVQDDQRSFALGLQWIKVRLLGTIPAPLIFGALI 623
            |.||||..|..|...||:...::|:....|:.|.....|.:||:.:...|.||::|..|:|.:..
  Rat   555 CLTLPLLFAFYFAATVFSNFCSVPSFMIVLKSVPASWNSMSLGVTYTIWRFLGSVPDHLLFESTS 619

  Fly   624 DESCILWQ-ESCDKDAGGACLVYD 646
            |.:|..|. .||.:.  |.|.:|:
  Rat   620 DYTCNFWDINSCGEK--GRCWIYN 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp26F	NP_609055.2	MFS_SLCO4_OATP4	64..589	CDD:340961	146/543 (27%)
Slco6d1	XP_017452073.1	MFS	84..585	CDD:475125	146/543 (27%)