Protein Alignment Oatp26F and slco1d1

DIOPT Version :10

• Sequence 1: NP_609055.2
• Gene: Oatp26F / 33927
• FlyBaseID: FBgn0051634
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_001335015.1
• Gene: slco1d1 / 326845
• ZFINID: ZDB-GENE-030131-5044
• Length: 689
• Species: Danio rerio
• Alignment Length: 662
• Identity: 191/662 - (28%)
• Similarity: 308/662 - (46%)
• Gaps: 106/662 - (16%)

  Fly    62 CTAKWALF-----WLCWGGALQGLIVNGLINVSISTIERRFGLRSRQMGLVASGYDLASFACLVP 121
            |.:|..:|     ::.:..|.||    ..:..|::.|||||.:.|..:|.:...:::.:...:..
Zfish    10 CCSKLKMFLAAMCFVFFAKAFQG----SYMKSSVTQIERRFDVPSSLIGFIDGSFEIGNLFVIAF 70

  Fly   122 VTYYGGRRGASKPRFIAIGLIVMGMGSLVFLLPNFLVGNYR--ATI----AEANVCETTGLPFNS 180
            |:|:|.:  ..:||.||.|.:||..||.:..:|:|..|.|:  :||    |..|..|.. ||..:
Zfish    71 VSYFGAK--LHRPRLIAAGCLVMSAGSFITAMPHFFQGQYKYESTISHFSASVNGTENV-LPCLT 132

  Fly   181 NSS----------QSMTACELNAMGEGQSENLTWTVWLFL-AAQLLHGAGASPLFTLGVTYIDEN 234
            |:|          :|...||     :..|.:|    |||: ...:|.|.|.:|:..||::|:|:.
Zfish   133 NASLAQDSEIPTVESQAECE-----KASSSSL----WLFVFLGNMLRGIGETPVMPLGLSYLDDF 188

  Fly   235 VSKKMSSVYLGIYYTMATVGPAIGYVFGGQLLLIYTDWMTVDPVQLSLTSDSKVWIGAWWLGFIF 299
            ..::.::.||.:..|:..:||..|::.|.....:|.|..|||...:::......|:|||||||:.
Zfish   189 SREENTAFYLALIQTVGIMGPMFGFMLGSFCAKLYVDIGTVDLDSITINYKDSRWVGAWWLGFLV 253

  Fly   300 AAAMCLLIALPIFGYPKLL-----------PGA-EKLQLERV------------SEAHATISE-A 339
            ...:.||..:|.:..||.|           ||| |..:.||.            ..|..|:|. |
Zfish   254 TGGVMLLAGIPFWFLPKSLTRQGEPESEKKPGAPEGGEQERFIPDNNKHNPPASKPAPVTMSALA 318

  Fly   340 DDSSNVVRGLPRAVLSLLANPTFFFLNLAGATEGLVIAGFAAFLPKQIENQFSISPMYSALVMGL 404
            .|.      || ::..|.:|..:..|...|..:.....|...|.||.:|..:..|...:..::|:
Zfish   319 KDF------LP-SLKKLFSNTIYVLLVCTGLIQVSGFIGMITFKPKFMEQVYGQSASRAIFLIGI 376

  Fly   405 ITVPAGGGGTFLGGYLVKKWNLACRGIIKMCLLATTVA-ALFTICFLVSCPNPKFAGVTTGYKMQ 468
            :.:||...|...||:::|::.:...|..|:|::|:.:| ....|.:.:.|.|.:.||:|..|:..
Zfish   377 MNLPAVALGIVTGGFIMKRFKVNVLGAAKICIVASVLAFCSMLIQYFLQCDNSQVAGLTVTYQGA 441

  Fly   469 P--SSDSPALVASCNSNCGCSRTNYDPICGVDGVMYYSPCYAGCVQEEHANSLKRYHNCSCIEQV 531
            |  |..:..|::.||..|.||..::||||..:||.|.|||.|||...........:||||||
Zfish   442 PEVSYQTETLISQCNIGCSCSLKHWDPICASNGVTYTSPCLAGCQTSTGIGKEMVFHNCSCI--- 503

  Fly   532 GFVDDGNPSSEA--PHFRPDATNRKC--DSTCQTL-PLFVALCFILMVFTFLATMPALSATLRCV 591
                     .||  |:....|...:|  .|.|..: .:::|:..|...|:.:...|.....||.:
Zfish   504 ---------GEALLPYTNMSAVLGQCPRKSDCDFMFKIYMAVTVIGAFFSAVGATPGYIILLRSI 559

  Fly   592 QDDQRSFALGLQWIKVRLLGTIPAPLIFGALIDESCILW-QESCDKDAGGACLVYDN-------- 647
            ..:.:|.|||:..:.||.||.||.|:.||||||::|:.| .:.|  ...|||.:||:
Zfish   560 TPELKSLALGMHTLIVRTLGGIPPPIYFGALIDKTCLKWGLKQC--GGRGACRIYDSGAFRNAFL 622

  Fly   648 -----FYISRYM 654
                 .|.|.|:
Zfish   623 GLIYALYSSSYL 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp26F	NP_609055.2	MFS_SLCO4_OATP4	64..589	CDD:340961	160/579 (28%)
slco1d1	NP_001335015.1	MFS	14..558	CDD:475125	160/578 (28%)