Protein Alignment Oatp26F and Slco1a6

DIOPT Version :10

• Sequence 1: NP_609055.2
• Gene: Oatp26F / 33927
• FlyBaseID: FBgn0051634
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_076207.1
• Gene: Slco1a6 / 28254
• MGIID: 1351906
• Length: 670
• Species: Mus musculus
• Alignment Length: 631
• Identity: 187/631 - (29%)
• Similarity: 315/631 - (49%)
• Gaps: 50/631 - (7%)

  Fly    62 CTAKWALFWLCWGGALQGLIVNGL-INVSISTIERRFGLRSRQMGLVASGYDLASFACLVPVTYY 125
            |.||..:|.|....|....|::|: ::..::.:||:|.:.:..:||:...:::.:...:|.|:|:
Mouse    15 CFAKIKVFLLALIWAYISKILSGVYMSTMLTQLERQFNISTSIVGLINGSFEMGNLLVIVFVSYF 79

  Fly   126 GGRRGASKPRFIAIGLIVMGMGSLVFLLPNFLVGNYRATIAEANVCETTGLPFNS-----NSSQS 185
            |.:  ..:|..|.:|..|||:|..:..||:||:|.|.   .|..:..|:.|..||     |.||:
Mouse    80 GTK--LHRPIMIGVGCAVMGLGCFIISLPHFLMGRYE---YETTISPTSNLSSNSFLCVENRSQT 139

  Fly   186 MTACELNAMGEGQSENLTWTVWLFLAAQLLHGAGASPLFTLGVTYIDENVSKKMSSVYLGIYYTM 250
            :...:..|....:.::|.|.  ..|...::.|.|.:|:..||::||::....:.|.:|:||....
Mouse   140 LKPTQDPAECVKEIKSLMWI--YVLVGNIIRGIGETPIMPLGISYIEDFAKSENSPLYIGILEVG 202

  Fly   251 ATVGPAIGYVFGGQLLLIYTDWMTVDPVQLSLTSDSKVWIGAWWLGFIFAAAMCLLIALPIFGYP 315
            ..:||.:||:.|.....||.|..:|:...|::|.....|:||||:||:..|.:.:|.::|.|.:|
Mouse   203 KMIGPILGYLMGPFCANIYVDTGSVNTDDLTITPTDTRWVGAWWIGFLVCAGVNVLTSIPFFFFP 267

  Fly   316 KLLPGAEKLQ-----LERVSEAHATISEADDSSNVVRGLPRAVLSLLANPTFFFLNLAGATEGLV 375
            |.|| .|.||     .|...|........:::..:::.....:.:|..||.:....|....:...
Mouse   268 KTLP-KEGLQDNGDGTENAKEEKHRDKAKEENQGIIKEFFLMMKNLFCNPIYMLCVLTSVLQVNG 331

  Fly   376 IAGFAAFLPKQIENQFSISPMYSALVMGLITVPAGGGGTFLGGYLVKKWNLACR--GIIKMCLLA 438
            :|....:.||.:|:.|.||...:..::||.|.|:...|..:.|:::||..:..:  .||.:||..
Mouse   332 VANIVIYKPKYLEHHFGISTAKAVFLIGLYTTPSVSAGYLISGFIMKKLKITLKKAAIIALCLFM 396

  Fly   439 TTVAALFTIC-FLVSCPNPKFAGVTTGYK-MQPSSD-SPALVASCNSNCGCSRTNYDPICGVDGV 500
            :  ..|.::| |:::|.....||:||.|: :|.|.| ....::.||:.|.|....:||:||.:|:
Mouse   397 S--ECLLSLCNFMLTCDTTPIAGLTTSYEGIQQSFDMENKFLSDCNTRCNCLTKTWDPVCGNNGL 459

  Fly   501 MYYSPCYAGCVQEEHANSLKRYHNCSCIEQVGFVDDGNPSSEAPHFR--PDATNRKCDSTCQTLP 563
            .|.|||.|||.:.....:...:.|||||.     ..||.|:.....:  ||..|:        |.
Mouse   460 AYMSPCLAGCEKSVGTGANMVFQNCSCIR-----SSGNSSAVLGLCKKGPDCANK--------LQ 511

  Fly   564 LFVALCFILMVFTFLATMPALSATLRCVQDDQRSFALGLQWIKVRLLGTIPAPLIFGALIDESCI 628
            .|:.:......|..|||:|.....|||::.:::|..:|||...:||...||||:.||||||.:|:
Mouse   512 YFLIITVFCCFFYSLATIPGYMVFLRCMKSEEKSLGIGLQAFFMRLFAGIPAPIYFGALIDRTCL 576

  Fly   629 LWQE-SCDKDAGGACLVYDNFYISR-YMWLLALICKLGSVV---FF 669
            .|.. .|.:.  |||..|:.....| |:.|.|.:  .||::   ||
Mouse   577 HWGTLKCGEP--GACRTYEVSSFRRLYLGLPAAL--RGSIILPSFF 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp26F	NP_609055.2	MFS_SLCO4_OATP4	64..589	CDD:340961	152/542 (28%)
Slco1a6	NP_076207.1	oat	1..625	CDD:273279	187/631 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	633..670