Protein Alignment Oatp26F and Slco1b2

DIOPT Version :10

• Sequence 1: NP_609055.2
• Gene: Oatp26F / 33927
• FlyBaseID: FBgn0051634
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_065241.1
• Gene: Slco1b2 / 28253
• MGIID: 1351899
• Length: 689
• Species: Mus musculus
• Alignment Length: 617
• Identity: 200/617 - (32%)
• Similarity: 310/617 - (50%)
• Gaps: 57/617 - (9%)

  Fly    60 RFCTAKWALFWLCWGGALQGLIVNGLINVSISTIERRFGLRSRQMGLVASGYDLASFACLVPVTY 124
            |...|..:..::|  .||.|:|:..    ||:.|||||.:.|...||:..|:::.:...:|.|:|
Mouse    26 RIFLAALSFSYIC--KALGGVIMKS----SITQIERRFDIPSSISGLIDGGFEIGNLLVIVFVSY 84

  Fly   125 YGGRRGASKPRFIAIGLIVMGMGSLVFLLPNFLVGNYR-ATIAEANVCETTGLPFNSNSSQSMTA 188
            :|.:  ..:|:.|..|..:||:||::..||:|.:|.|| ||..:.:....:.|....|.:.|:|.
Mouse    85 FGSK--LHRPKLIGTGCFIMGIGSILTALPHFFMGYYRYATENDISSLHNSTLTCLVNQTTSLTG 147

  Fly   189 CELNAMGEGQSENLTWTVWLF-LAAQLLHGAGASPLFTLGVTYIDENVSKKMSSVYLGIYYTMAT 252
            .....|.:|..:......|:: |...:|.|.|.:|:..|||:|||:...:..||:|||..:|:|.
Mouse   148 TSPEIMEKGCEKGSNSYTWIYVLMGNMLRGIGETPIVPLGVSYIDDFAKEGNSSMYLGTLHTIAM 212

  Fly   253 VGPAIGYVFGGQLLLIYTDWMTVDPVQLSLTSDSKVWIGAWWLGFIFAAAMCLLIALPIFGYPKL 317
            :||.:|::.......:|.|...||...:.:|.....|:||||||||....:|::.::|.|..||:
Mouse   213 IGPILGFIMSSVFAKLYVDVGYVDLRSVRITPQDARWVGAWWLGFIVNGLLCIICSIPFFFLPKI 277

  Fly   318 LPGAEKLQLERVSEAHATISEADDSSNVV--------------RGLPRAVLSLLANPTF-FFLNL 367
               .::.|.||.:.|...:.:.|:..|.|              .|...::.|:|.|..: .||.|
Mouse   278 ---PKRSQKERKNSASLHVLKTDEDKNPVTNPTTQEKQAPANLTGFLWSLRSILTNEQYVIFLIL 339

  Fly   368 AGATEGLVIAGFAAFLPKQIENQFSISPMYSALVMGLITVPAGGGGTFLGGYLVKKWNLACRGII 432
            ........|..| .:|.|.||.||..:...:..::|:||:|....|.||||||:|:..|...||.
Mouse   340 TLLQISSFIGSF-TYLFKFIEQQFGQTASQANFLLGVITIPTMASGMFLGGYLIKRLKLTLLGIT 403

  Fly   433 KMCLLATTVAALFTIC-FLVSCPNPKFAGVTTGYK-MQPSS---DSPALVASCNSNCGCSRTNYD 492
            |.....||:|.:|.:. ||:.|.|..|||:|..|. |.|..   |.|  ::.|||:|.|.:..::
Mouse   404 KFVFFTTTMAYVFYLSYFLLICENKAFAGLTLTYDGMNPVDSHIDVP--LSYCNSDCICDKNQWE 466

  Fly   493 PICGVDGVMYYSPCYAGCVQEEHANSLK--RYHNCSCIEQVGFVDDGNPSS---EAPHFRPDATN 552
            |:||.:||.|.|||.|||........|.  .:::|||:...|| ..||.|:   |.|.
Mouse   467 PVCGENGVTYISPCLAGCKSFRGDKKLMNIEFYDCSCVSGSGF-QKGNHSARLGECPR------- 523

  Fly   553 RKCDSTCQTLPLF-VALCFILMVFTFLATMPALSATLRCVQDDQRSFALGLQWIKVRLLGTIPAP 616
                ..|:|...| :....|:..||.|.:...:...:|.||.:.:|..:|...:.||.||.|.||
Mouse   524 ----DKCKTKYYFYITFQVIISFFTALGSTSLMLILIRSVQPELKSLGMGFHSLVVRTLGGILAP 584

  Fly   617 LIFGALIDESCILWQ-ESCDKDAGGACLVYDN 647
            :.:|||||.:|:.|. .||  .|.|||.:|::
Mouse   585 VYYGALIDRTCMKWSVTSC--GARGACRLYNS 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp26F	NP_609055.2	MFS_SLCO4_OATP4	64..589	CDD:340961	173/552 (31%)
Slco1b2	NP_065241.1	MFS	26..557	CDD:475125	174/556 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	658..689