Protein Alignment Oatp26F and Slco2a1

DIOPT Version :10

• Sequence 1: NP_609055.2
• Gene: Oatp26F / 33927
• FlyBaseID: FBgn0051634
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_073158.2
• Gene: Slco2a1 / 24546
• RGDID: 3051
• Length: 644
• Species: Rattus norvegicus
• Alignment Length: 672
• Identity: 203/672 - (30%)
• Similarity: 328/672 - (48%)
• Gaps: 82/672 - (12%)

  Fly    30 SRVGSSISGPDSDAECQRFGWCGWNPAWLQRFCTAKWALFWLCWGGALQ--GLIVNGLINVSIST 92
            :|.||..|.. .|..|.|           ..|...|  :|.|| .|.||  .|:.:.....|::|
  Rat     9 ARQGSGTSSV-PDRRCPR-----------SVFSNIK--VFVLC-HGLLQLCQLLYSAYFKSSLTT 58

  Fly    93 IERRFGLRSRQMGLVASGYDLASFACLVPVTYYGGRRGASKPRFIAIGLIVMGMGSLVFLLPNFL 157
            ||:||||.|...||::|..::::...::.::|:|.|  .::||.|.||.:::..|:.|..||:||
  Rat    59 IEKRFGLSSSSSGLISSLNEISNATLIIFISYFGSR--VNRPRMIGIGGLLLAAGAFVLTLPHFL 121

  Fly   158 VGNYRATIAEANVCETTGLPFNSNSSQSMTACE--LNAMGEGQSENL-------TWTVW-LFLAA 212
            ...|:.|       .||.   .:.||.....|:  |.|:...:..:.       |.::| |.:.|
  Rat   122 SEPYQYT-------STTD---GNRSSFQTDLCQKHLPALPPSKCHSTVPDTHKETSSLWGLMVVA 176

  Fly   213 QLLHGAGASPLFTLGVTYIDENVSKKMSSVYLGIYYTMATVGPAIGYVFGGQLLLIYTDWMTVDP 277
            |||.|.|..|:...|::|:|:......|.:|:.|.:.:|..|||.||:.|..:|.|:.|:..||.
  Rat   177 QLLAGIGTVPIQPFGISYVDDFAEPTNSPLYISILFAIAVFGPAFGYLLGSVMLRIFVDYGRVDT 241

  Fly   278 VQLSLTSDSKVWIGAWWLGFIFAAAMCLLIALPIFGYPKLLP-GAEKLQLERVSEAHATISEADD 341
            ..::|:.....||||||||.:.::...::.:||.|.:|:.:. ||     ||...|..|:...:|
  Rat   242 ATVNLSPGDPRWIGAWWLGLLISSGFLIVTSLPFFFFPRAMSRGA-----ERSVTAEETMKTEED 301

  Fly   342 SS-----NVVRGLPRAVLSLLANPTFFFLNLAGATEGLVIAGFAAFLPKQIENQFSISPMYSALV 401
            .|     :.::..||..|.||.||.|..:.|:..|...||||.:.||.|.:|.|:..:..|:..:
  Rat   302 KSRGSLMDFIKRFPRIFLRLLMNPLFMLVVLSQCTFSSVIAGLSTFLNKFLEKQYGATAAYANFL 366

  Fly   402 MGLITVPAGGGGTFLGGYLVKKWNLACRGIIKMCLLATTVAALFTI-CFLVSCPNPKFAGVTTGY 465
            :|.:.:||...|...||.|:|::....:.|.::.....|::.:..: .|.:.|.....|.|
  Rat   367 IGAVNLPAAALGMLFGGILMKRFVFPLQTIPRVAATIITISMILCVPLFFMGCSTSAVAEV---- 427

  Fly   466 KMQPSSDS---PALVASCNSNCGCSRTNYDPICGVDGVMYYSPCYAGCVQEEHANSLKR---YHN 524
             ..||:.|   |....:|..:|.|..:.:.|:||.:||.|.|||:|||.....::...:   |.|
  Rat   428 -YPPSTSSSIHPQQPPACRRDCSCPDSFFHPVCGDNGVEYVSPCHAGCSSTNTSSEASKEPIYLN 491

  Fly   525 CSCIEQVGFVDDGNPSSEAPHFRPDATNRKCDSTCQ--TLPLFVALCFILMVFTFLATMPALSAT 587
            |||:       .|..:|        |....|.::|.  .||....:.|..:: ..::..|.....
  Rat   492 CSCV-------SGGSAS--------AKTGSCPTSCAQLLLPSIFLISFAALI-ACISHNPLYMMV 540

  Fly   588 LRCVQDDQRSFALGLQWIKVRLLGTIPAPLIFGALIDESCILWQESCDKDAGGACLVYDNFYI-S 651
            ||.|..|::|||:|:|::.:|||..:|||.::|.|||.||:.|...| ....|||..|||..: :
  Rat   541 LRVVNQDEKSFAIGVQFLLMRLLAWLPAPSLYGLLIDSSCVRWNYLC-SGRRGACAYYDNDALRN 604

  Fly   652 RYMWLLALICKLGSVVFFACAW 673
            ||:.|..:...||:::.|..:|
  Rat   605 RYLGLQMVYKALGTLLLFFISW 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp26F	NP_609055.2	MFS_SLCO4_OATP4	64..589	CDD:340961	159/551 (29%)
Slco2a1	NP_073158.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		4/11 (36%)
		MFS_SLCO2A_OATP2A	30..542	CDD:341019	159/552 (29%)