Protein Alignment Oatp26F and Slco2a1

DIOPT Version :10

• Sequence 1: NP_609055.2
• Gene: Oatp26F / 33927
• FlyBaseID: FBgn0051634
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_201571.2
• Gene: Slco2a1 / 24059
• MGIID: 1346021
• Length: 643
• Species: Mus musculus
• Alignment Length: 636
• Identity: 201/636 - (31%)
• Similarity: 323/636 - (50%)
• Gaps: 73/636 - (11%)

  Fly    68 LFWLCWGGALQ--GLIVNGLINVSISTIERRFGLRSRQMGLVASGYDLASFACLVPVTYYGGRRG 130
            :|.|| .|.||  .|:.:.....|::|||:||||.|...||::|..::::...::.|:|:|.|
Mouse    33 VFVLC-HGLLQLCQLLYSAYFKSSLTTIEKRFGLSSSSSGLISSLNEISNAILIIFVSYFGSR-- 94

  Fly   131 ASKPRFIAIGLIVMGMGSLVFLLPNFLVGNYRATIAEANVCETTGLPFNSNSSQSMT-ACELNAM 194
            .::||.|.||.:::..|:.|..||:||...|:       ...||.    .|||...| .|:.:..
Mouse    95 VNRPRMIGIGGLLLAAGAFVLTLPHFLSEPYQ-------YASTTA----GNSSHFQTDLCQKHLP 148

  Fly   195 G-----------EGQSENLTWTVW-LFLAAQLLHGAGASPLFTLGVTYIDENVSKKMSSVYLGIY 247
            |           :.|.|  |.::| |.:.||||.|.|..|:...|::|:|:......|.:|:.|.
Mouse   149 GLLPSKCHSTVPDTQKE--TSSMWSLMVVAQLLAGVGTVPIQPFGISYVDDFAEPTNSPLYISIL 211

  Fly   248 YTMATVGPAIGYVFGGQLLLIYTDWMTVDPVQLSLTSDSKVWIGAWWLGFIFAAAMCLLIALPIF 312
            :.:|..|||.||:.|..:|.|:.|:..||...::|:.....||||||||.:.::...::.:||.|
Mouse   212 FAIAVFGPAFGYLLGSVMLRIFVDYGRVDTATVNLSPGDPRWIGAWWLGLLISSGFLIVTSLPFF 276

  Fly   313 GYPKLLP-GAEKLQLERVSEAHATISEADDSS-----NVVRGLPRAVLSLLANPTFFFLNLAGAT 371
            .:|:.:. |||:..:     |..|:...:|.|     :.::..||..|.||.||.|..:.|:..|
Mouse   277 FFPRAMSRGAERSVI-----AEETMKMEEDKSRGSLMDFIKRFPRIFLRLLMNPLFMLVVLSQCT 336

  Fly   372 EGLVIAGFAAFLPKQIENQFSISPMYSALVMGLITVPAGGGGTFLGGYLVKKWNLACRGIIKMCL 436
            ...||||.:.||.|.:|.|:..|..|:.|::|.:.:||...|...||.|:|::....:.|.::..
Mouse   337 FSSVIAGLSTFLNKFLEKQYDASAAYANLLIGAVNLPAAALGMLFGGILMKRFVFPLQTIPRVAA 401

  Fly   437 LATTVAALFTIC---FLVSCPNPKFAGVTTGYKMQPSSDSPALVASCNSNCGCSRTNYDPICGVD 498
            ...|::.:  :|   |.:.|..|..|.|..  ...|||..|...| |..:|.|..:.:.|:||.:
Mouse   402 TIMTISII--LCAPLFFMGCSTPAVAEVYP--PSTPSSIHPQPPA-CRRDCLCPDSVFHPVCGDN 461

  Fly   499 GVMYYSPCYAGCVQEEHANSLKR---YHNCSCIEQVGFVDDGNPSSEAPHFRPDATNRKCDSTCQ 560
            ||.|.|||:|||.....:::..:   |.||||:       .|..:|        |....|.::|.
Mouse   462 GVEYLSPCHAGCSSLNVSSAASKQPIYLNCSCV-------TGGSAS--------AKTGSCPTSCA 511

  Fly   561 --TLPLFVALCFILMVFTFLATMPALSATLRCVQDDQRSFALGLQWIKVRLLGTIPAPLIFGALI 623
              .||....:.|:.:: ..::..|.....||.|..|::|||:|:|::.:|||..:|:|.::|.||
Mouse   512 QLLLPSIFLISFVALI-ACVSHNPLYMMVLRVVNQDEKSFAIGVQFLLMRLLAWLPSPSLYGLLI 575

  Fly   624 DESCILWQESCDKDAGGACLVYDNFYI-SRYMWLLALICKLGSVVFFACAW 673
            |.|||.|...| ....|||..|||..: :||:.|..:...||:::.|..:|
Mouse   576 DSSCIRWNYLC-SGRRGACAYYDNDALRNRYLGLQVIYKVLGTLLLFFISW 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp26F	NP_609055.2	MFS_SLCO4_OATP4	64..589	CDD:340961	165/549 (30%)
Slco2a1	NP_201571.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		MFS_SLCO2A_OATP2A	30..541	CDD:341019	165/549 (30%)