Protein Alignment Oatp26F and Slco4c1

DIOPT Version :10

• Sequence 1: NP_609055.2
• Gene: Oatp26F / 33927
• FlyBaseID: FBgn0051634
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_766246.1
• Gene: Slco4c1 / 227394
• MGIID: 2442784
• Length: 722
• Species: Mus musculus
• Alignment Length: 682
• Identity: 256/682 - (37%)
• Similarity: 379/682 - (55%)
• Gaps: 50/682 - (7%)

  Fly     7 ELDSSIAVAPKCSNVNNNNSARSSRVGSSISGPDSDAECQRFGWCGWNPAWLQRFCTAKWALFWL 71
            |...|...:|..||...::....|::.....||     |   ||.|::|..|||..|.:..|...
Mouse    51 EPQKSTEPSPPSSNPPASDEPPGSQLSELEEGP-----C---GWRGFHPQCLQRCNTPQGFLLHY 107

  Fly    72 CWGGALQGLIVNGLINVSISTIERRFGLRSRQMGLVASGYDLASFACLVPVTYYGGRRGASKPRF 136
            |.....||::||||:|:||||||:|:.::|...||::|.||: ||..|.....:.|.|| .|||:
Mouse   108 CLLALTQGIVVNGLVNISISTIEKRYEMKSSLTGLISSSYDI-SFCVLSLFVSFFGERG-HKPRW 170

  Fly   137 IAIGLIVMGMGSLVFLLPNFLVGNYRATIAEANVCETTGLPFNSNSSQSMTACELNAMGEGQSEN 201
            :|....::|:|:|||.||:|..|.|..    .::.|.|.|..||....|.|:...|..
Mouse   171 LAFASFMIGLGALVFSLPHFFSGRYEL----GSIFEDTCLTRNSTRCSSSTSLLSNYF------- 224

  Fly   202 LTWTVWLFLAAQLLHGAGASPLFTLGVTYIDENVSKKMSSVYLGIYYTMATVGPAIGYVFGGQLL 266
                 ::|:..|||.|.|.:||:|||..:||::|....||:|:||.|:|:.:|||||||.|||||
Mouse   225 -----YVFVLGQLLLGTGGTPLYTLGTAFIDDSVPTHKSSLYIGIGYSMSILGPAIGYVLGGQLL 284

  Fly   267 LIYTDWMTVDPVQLS-LTSDSKVWIGAWWLGFIFAAAMCLLIALPIFGYPKLLPGAEKLQLERVS 330
            .:|.|   :...|.| ||.|...|:||||:||:.|......:.:|...:||.|||..|:|..:.|
Mouse   285 TMYID---IAMGQSSDLTEDDPRWLGAWWIGFLLAWLFAWSLIMPFSCFPKHLPGTAKIQAGKTS 346

  Fly   331 EAHATISEA-----DDSSNVVRGLPRAVLSLLANPTFFFLNLAGATEGLVIAGFAAFLPKQIENQ 390
            :.|...|.:     ::....::..|.||.:|:.|..|..|.|:..:|.|:..|||.||||.||||
Mouse   347 QTHQNNSTSFQHTDENFGKSIKDFPTAVKNLMRNTVFICLVLSTTSEALITTGFATFLPKFIENQ 411

  Fly   391 FSISPMYSALVMGLITVPAGGGGTFLGGYLVKKWNLACRGIIKMCLLATTVAALFTICFL-VSCP 454
            |.::..::|.:.|.:.:|....|..|||.||.|:.:.|:..:|..|..:.||.:.:..|: ..|.
Mouse   412 FGLTSSFAATLGGAVLIPGAALGQILGGVLVSKFKMKCKNTMKFALCTSGVALVLSFVFIYAKCE 476

  Fly   455 NPKFAGVTTGYKMQPSSDSPALVASCNSNCGCSRTNYDPICGVDGVMYYSPCYAGCVQEEHANSL 519
            |..||||:..|  ..:.:...|.|.||:||.|.|:.|.|:||.||:.|:|||:|||:........
Mouse   477 NEPFAGVSESY--NGTGEMGNLTAPCNANCNCLRSYYYPLCGSDGIQYFSPCFAGCLNSVSNRKP 539

  Fly   520 KRYHNCSCIEQVGFVDDGNPSSEAPHFRPDATNRKCDSTCQTLPLFVALCFILMVFTFLATMPAL 584
            |.|:||||||:     ....::|:..|  :|...||.:.|..||:|:.:.||.::|||:|..|..
Mouse   540 KVYYNCSCIER-----KITSTAESTDF--EAKAGKCRTRCSNLPIFLGIFFITVIFTFMAGTPIT 597

  Fly   585 SATLRCVQDDQRSFALGLQWIKVRLLGTIPAPLIFGALIDESCILWQESCDKDAG--GACLVYDN 647
            .:.||||....||.|||:|::.:|||||||.|:|||.:||.:|:||..:   :.|  |||.:|||
Mouse   598 VSILRCVNHRHRSLALGVQFMLLRLLGTIPGPIIFGVIIDSTCVLWDVN---ECGIKGACWIYDN 659

  Fly   648 FYISRYMWLLALICKLGSVVFFACAWWFYVPP 679
            ..::..:..:::.||:.::.|...|...|.||
Mouse   660 IKMAHMLVAISVTCKVITIFFNGLAIVLYKPP 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp26F	NP_609055.2	MFS_SLCO4_OATP4	64..589	CDD:340961	199/531 (37%)
Slco4c1	NP_766246.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..81		6/29 (21%)
		MFS_SLCO4C_OATP4C	100..602	CDD:341021	199/531 (37%)