Protein Alignment Oatp26F and Y70G10A.3

DIOPT Version :10

• Sequence 1: NP_609055.2
• Gene: Oatp26F / 33927
• FlyBaseID: FBgn0051634
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_499267.1
• Gene: Y70G10A.3 / 190573
• WormBaseID: WBGene00013499
• Length: 690
• Species: Caenorhabditis elegans
• Alignment Length: 661
• Identity: 225/661 - (34%)
• Similarity: 349/661 - (52%)
• Gaps: 57/661 - (8%)

  Fly    40 DSDAECQRFGWCGWNPAWLQRFCTAKWALFWLCWGGALQGLIVNGLINVSISTIERRFGLRSRQM 104
            :.|||....|:....|:|||.|..||..|..|.....:|..:||.:..|.:||:||||.:.|...
 Worm    23 EDDAEKLLCGYGACTPSWLQGFHNAKCLLVVLGICAFIQSFVVNAIFPVGLSTLERRFKMTSTHT 87

  Fly   105 GLVASGYDLASFACLVPVTYYG--GRRGASKPRFIAIGLIVMGMGSLVFLLPNFLVGNYRATIAE 167
            |:::|.||.|....:.||.::|  |.:|    |:|..|.::|.:|||:..||:::|..|...:.:
 Worm    88 GIISSWYDFAVLLVVFPVCHWGNNGHKG----RWIGWGGVIMALGSLICALPHWMVDIYHPDVND 148

  Fly   168 ANVCETTGLPFNSNSSQSMTACELNAMGEGQSENLTWTVWLFLAAQLLHGAGASPLFTLGVTYID 232
            .    |....|...:::....|    .|:..|.......|:|:..|.|||.|::|||::|.||:|
 Worm   149 L----TNQTDFGQCANRDDPEC----AGKPHSSWFNPYFWMFILGQTLHGVGSTPLFSIGTTYMD 205

  Fly   233 ENVSKKMSSVYLGIYYTMATVGPAIGYVFGGQLLLIYTDWMTVDPVQLSLTSDSKVWIGAWWLGF 297
            ||||:|.|.|||.|:..:.:.||.||...||.||.:|.|:..|:.:.:. .||.: |:||||:||
 Worm   206 ENVSQKASPVYLAIHAVLTSFGPVIGVFAGGFLLNLYDDFDRVERIPME-RSDPR-WVGAWWVGF 268

  Fly   298 IFAAAMCLLIALPIFGYPKLLPGAEKLQLERVSEAHATISEADDSSNVVRG---LPRAVLSLLAN 359
            |.::...|:||.||..:.:.||.|::.:.:.|::.|  ::..|.::...|.   ||..|..:|:|
 Worm   269 IISSISALMIAFPILAFARELPEAKRHRAKDVNQCH--VANGDVNAKAPRDLMKLPACVWKILSN 331

  Fly   360 PTFFFLNLAGATEGLVIAGFAAFLPKQIENQFSISPMYSALVMGLITVPAGGGGTFLGGYLVKKW 424
            |||......|..|.::|.|||||:||.:|...|.:|..::.:..:: :.|...|..:||.::::.
 Worm   332 PTFLVCIFVGIFESIIINGFAAFMPKILETLLSTNPTLASYLSSVV-IFAAATGVMVGGTIIRQL 395

  Fly   425 NLACRGIIKMCLLATTVAALFTICFLVSCPNPKFAGVTTGY------KMQPSSDSPALVASCNSN 483
            .|...|::||.::....|.|||...|..||..:|.|:..||      ||...|.|    ::||::
 Worm   396 KLQVGGMLKMIIVCHVFALLFTTGLLSHCPQREFVGINLGYEDLSIEKMHDFSIS----STCNAD 456

  Fly   484 CGCSRTNYDPICGVD-GVMYYSPCYAGCVQEEHANSLKRYHNCSCIEQVGFVDDGNPSSEAPH-- 545
            |.| :..::|:|..: |.||||.|:|||......:...::..|.|:          .|:...|
 Worm   457 CHC-KMEWNPVCDRNTGHMYYSACHAGCTGRTTIDGSSQWSGCGCL----------TSNSTFHNL 510

  Fly   546 -----FRPDATNR-KCDSTC--QTLPLFVALCFILMVFTFLATMPALSATLRCVQDDQRSFALGL 602
                 ..||..|: .|...|  :...|.|.| ||.:|.:|.:.:|.....||.|..|||:.|||:
 Worm   511 IHGIKEHPDVLNQGYCHQDCGYREYILMVTL-FITVVASFASGIPTQQIMLRVVPFDQRTLALGV 574

  Fly   603 QWIKVRLLGTIPAPLIFGALIDESCILWQESCDKDAGGACLVYDNFYISRYMWLLALICKLGSVV 667
            .|..|||||.||..::||.:||.:|:.|.|||.|  ..:|||||.|.:|..:..||::|||.|::
 Worm   575 NWTFVRLLGFIPGGILFGIIIDTACLEWGESCGK--ATSCLVYDPFKLSWTITGLAIVCKLLSIL 637

  Fly   668 FFACAWWFYVP 678
            .....:..|.|
 Worm   638 ATIIGYMTYRP 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp26F	NP_609055.2	MFS_SLCO4_OATP4	64..589	CDD:340961	174/546 (32%)
Y70G10A.3	NP_499267.1	MFS_SLCO4_OATP4	47..561	CDD:340961	174/546 (32%)