Protein Alignment Oatp26F and LOC1277223

DIOPT Version :10

• Sequence 1: NP_609055.2
• Gene: Oatp26F / 33927
• FlyBaseID: FBgn0051634
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: XP_001237849.3
• Gene: LOC1277223 / 1277223
• VectorBaseID: AGAMI1_010864
• Length: 687
• Species: Anopheles gambiae
• Alignment Length: 677
• Identity: 192/677 - (28%)
• Similarity: 305/677 - (45%)
• Gaps: 94/677 - (13%)

  Fly    35 SISG-PDSDAECQRFG-WCGWNPAWLQRFCTAKWALFWLCWGGALQGLIVNGLINV---SISTIE 94
            |||. .:.|.:|   | |....|.| ||..:.|  |:.|.:|  |.|.|:|...:.   :::|:|
Mosquito    26 SISAYSERDVQC---GFWVCRGPFW-QRLASKK--LYVLLFG--LMGCILNSTTSYFYGTLTTVE 82

  Fly    95 RRFGLRSRQMGLVASGYDLASFACLVPVTYYGGRRGASKPRFIAIGLIVMGMGSLVFLLPNFLVG 159
            :...:.||.:|::.:|.||:.....:.::||...|  .||.:||:|::.|.:...|..||:||..
Mosquito    83 KSIQISSRTVGIITAGSDLSFVLASLFLSYYASNR--RKPLWIAMGIVSMALSCFVNALPHFLFS 145

  Fly   160 NYRATIAEANVCE-TTGLPFNSNSSQSMTACELNAMGEGQSENLTWTVWLFLAAQLLHGAGASPL 223
            ..:|.: |.|:.. |.|........:....|.|: :|:.:.:     :.||..: .|.|.|.|..
Mosquito   146 KAQAEL-EQNLGNLTKGADNLCREDRLAPDCSLD-VGDIRPQ-----IVLFFGS-FLSGIGTSLY 202

  Fly   224 FTLGVTYIDENVSKKMSSVYLGIYYTMATVGPAIGYVFGGQLLLIYTDWMTVDPVQLSLTSDSKV 288
            ||||:||:|:||.|:.......:......:||.:|:.. ..|.|.|...:.|||   ........
Mosquito   203 FTLGLTYLDDNVRKEKVPFLSSLAAFGRRMGPLVGFSL-ASLCLKYFVHVGVDP---GYNQSDPR 263

  Fly   289 WIGAWWLGFIFAAAMCLLIALPIF-GYPKLLP-GAEKLQLERVSEAHATISEADDSSNVVRGLPR 351
            ||||||:|:: |....|:|..|.| .:||:|| .||::.|.|.:...:..|.|::.....|.:..
Mosquito   264 WIGAWWMGWL-ALGSTLIIIAPFFASFPKVLPRTAERISLSRQASRASGTSTAEEDVETNRKVSF 327

  Fly   352 A-----VLSLLANPTFFFLNLAGATEGLVIAGFAAFLP------KQIENQFSISPMYSALVMGLI 405
            :     |..|:.|..:.|.|:|.      |..|..::|      |.||.|:.::|..:.::.|..
Mosquito   328 SDMLVTVRRLVTNKAYVFNNVAS------IFYFFGYMPYFLFQAKYIEIQYRLTPSQANMITGST 386

  Fly   406 TVPAGGGGTFLGGYLVKKWNLACRGIIKMCLLATTVAALFTICFL-VSCPNPKFAGVTTGYKMQP 469
            ::.....|..:.|.:::|..::.|.:....::.:.::|...:.:. ..|.....|.:...
Mosquito   387 SLVFSALGILIAGMVIQKLRVSSRQLAGWNVITSILSAALIVGYAWFGCSALNNADIVAN----- 446

  Fly   470 SSDSPALVASCNSNCGCSRTNYDPICGVDGVMYYSPCYAGCVQEEHANSLK------RYHNCSCI 528
            |.|     |||:..|.|....|.||||.||..|.|||:|||     .:|||      .|.|||||
Mosquito   447 SQD-----ASCSLGCNCEFVKYAPICGSDGQTYLSPCHAGC-----RDSLKDPTGTTLYTNCSCI 501

  Fly   529 EQVGFVDDGNPSSEAPHFRPDATNRKCDSTCQTLPLFVALCFILMVF--------TFLATMPALS 585
            .......|.|.:|.    ...||...|...|.|...|..:|..|..|        .||
Mosquito   502 ASPTDDLDANFTSS----YGSATPGSCPVDCGTPFYFFLMCLCLNKFIGGTESAANFL------- 555

  Fly   586 ATLRCVQDDQRSFALGLQWIKVRLLGTIPAPLIFGALIDESCILWQESCDKDAGGACLVYDNFYI 650
            ..||||:...::.::|.......|...:|||::|||:||.:|:||..:|.|.  |.|.:||...:
Mosquito   556 IGLRCVEPRDKAISMGFSMAINTLFSFLPAPIVFGAIIDRTCVLWGRTCAKQ--GNCWLYDGEAL 618

  Fly   651 SRYM-WLLALICKLGSVVFFACAWWFY 676
            ...| :..|:...:|:.  |....|:|
Mosquito   619 RASMNYTAAVFVIIGTC--FDMGTWYY 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp26F	NP_609055.2	MFS_SLCO4_OATP4	64..589	CDD:340961	152/556 (27%)
LOC1277223	XP_001237849.3	None