Protein Alignment Oatp26F and Slco4a1

DIOPT Version :10

• Sequence 1: NP_609055.2
• Gene: Oatp26F / 33927
• FlyBaseID: FBgn0051634
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_683735.1
• Gene: Slco4a1 / 108115
• MGIID: 1351866
• Length: 723
• Species: Mus musculus
• Alignment Length: 679
• Identity: 300/679 - (44%)
• Similarity: 405/679 - (59%)
• Gaps: 58/679 - (8%)

  Fly    28 RSSRVGSSI----SGPDSDAECQRFGWCGWNPAWLQRFCTAKWALFWLCWGGALQGLIVNGLINV 88
            |||:....:    |||.:.. |   ||..:.|..||.|.|.|..||:||....|||:.|||.||.
Mouse    65 RSSQTAREVQYVSSGPQNSL-C---GWQAFTPKCLQVFNTPKGFLFFLCAASFLQGMTVNGFINT 125

  Fly    89 SISTIERRFGLRSRQMGLVASGYDLASFACLVPVTYYGGRRGASKPRFIAIGLIVMGMGSLVFLL 153
            .|::|||||.|.|.|.||:||.||:|:..||..|:|:||  ...|||::..|::|:|:|||||.|
Mouse   126 VITSIERRFDLHSYQSGLIASSYDIAACLCLTFVSYFGG--NGHKPRWLGWGVLVLGIGSLVFAL 188

  Fly   154 PNFLVGNYRATIAE---ANVCETTGLPFNSNSSQSMTACELNAMGEGQSENLTWTVWLFLAAQLL 215
            |:|..|.|...:.|   ...|.|         :||...|:.:|.|      |:....:|:..|||
Mouse   189 PHFTAGRYEVEMDEGLGTGTCLT---------NQSHVECKDSASG------LSNYRLIFMLGQLL 238

  Fly   216 HGAGASPLFTLGVTYIDENVSKKMSSVYLGIYYTMATVGPAIGYVFGGQLLLIYTDWMTVDPVQL 280
            ||.||:||:||||||:||||....|.:|:.|:||.|.:|||.||:.||.:|.:||:    ...:.
Mouse   239 HGVGATPLYTLGVTYLDENVKSSYSPIYIAIFYTAAILGPAAGYLIGGAMLNVYTE----VGQRT 299

  Fly   281 SLTSDSKVWIGAWWLGFIFAAAMCLLIALPIFGYPKLLPGAEKLQLERVSEA-----HATISEAD 340
            .||:||.:|:||||:||:.......|||:||.|||:.|||:::..:.|.:|.     |:..:.::
Mouse   300 ELTTDSPLWVGAWWIGFLGTGIAAFLIAIPILGYPRQLPGSQRYVVMRAAETQQLKDHSRGAVSN 364

  Fly   341 DS-SNVVRGLPRAVLSLLANPTFFFLNLAGATEGLVIAGFAAFLPKQIENQFSISPMYSALVMGL 404
            .: ...||.||.::..||.||||..|.||||||..:|||.:.|.||..|.|||:|...:|.:.|.
Mouse   365 PAFGKTVRDLPLSIWLLLRNPTFILLCLAGATEATLIAGMSTFGPKFFEAQFSLSASEAATLFGY 429

  Fly   405 ITVPAGGGGTFLGGYLVKKWNLACRGIIKMCLLATTVAALFTICFLVSCPNPKFAGVTTGY--KM 467
            :.||||||||.|||:||.|:.|...|||:.||..|..:.|....||:.|||...|||||||  .:
Mouse   430 LVVPAGGGGTLLGGFLVNKFKLRGSGIIRFCLFCTLTSLLAFFVFLMHCPNVHMAGVTTGYVGSL 494

  Fly   468 QPSSDSPALVASCNSNCGCSRTNYDPICGVDGVMYYSPCYAGCV--QEEHANSLKRYHNCSCIEQ 530
            .|..... |.|:||:...|...:|.|:||.||.||||||||||.  .|......|.|..||||.:
Mouse   495 LPKGQLD-LKAACNAIYCCQPKHYSPLCGSDGTMYYSPCYAGCPADAETDLGGQKVYRGCSCILE 558

  Fly   531 VGFVDDGNPSSEAPHFRPDATNRKCDSTCQTLPLFVALCFILMVFTFLATMPALSATLRCVQDDQ 595
            ......||           ||..||.||||:.|..:.|.|::::||||:::|||:||||||.|.|
Mouse   559 KASSGWGN-----------ATAGKCASTCQSKPFLLVLVFVVIIFTFLSSIPALTATLRCVSDRQ 612

  Fly   596 RSFALGLQWIKVRLLGTIPAPLIFGALIDESCILWQESCDKDAGGACLVYDNFYISRYMWLLALI 660
            ||||||:|||.||.||:||.|:.||.:||::|:|||:.|...  |:|.||:|..:||||.:..|.
Mouse   613 RSFALGIQWIVVRTLGSIPGPIAFGWVIDKACLLWQDQCGHQ--GSCFVYENEAMSRYMLIAGLT 675

  Fly   661 CKLGSVVFFACAWWFYVPPSKPLNANGKE 689
            .|:...:||..|::.|..||  ::::|.|
Mouse   676 FKVLGFLFFVAAYFLYKSPS--VSSDGLE 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp26F	NP_609055.2	MFS_SLCO4_OATP4	64..589	CDD:340961	236/537 (44%)
Slco4a1	NP_683735.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	23..64
		MFS	101..606	CDD:475125	236/537 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	700..723		2/3 (67%)