Protein Alignment Oatp26F and Slco1a5

DIOPT Version :10

• Sequence 1: NP_609055.2
• Gene: Oatp26F / 33927
• FlyBaseID: FBgn0051634
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_570931.1
• Gene: Slco1a5 / 108096
• MGIID: 1351865
• Length: 670
• Species: Mus musculus
• Alignment Length: 628
• Identity: 178/628 - (28%)
• Similarity: 307/628 - (48%)
• Gaps: 55/628 - (8%)

  Fly    62 CTAKWALFWLCWGGALQGLIVNGL-INVSISTIERRFGLRSRQMGLVASGYDLASFACLVPVTYY 125
            |.:|..:|.|....|.....::|: :|..::.|||:|.:.:..:||:...:::.:...::.|:|:
Mouse    15 CFSKIKMFLLALTCAYVSKSLSGIYMNSMLTQIERQFDIPTSIVGLINGSFEIGNLLLIILVSYF 79

  Fly   126 GGRRGASKPRFIAIGLIVMGMGSLVFLLPNFLVGNYRATIAEANVCETTGLPFNS-----NSSQS 185
            |.:  ..:|..|.||.::||:|..:..||:||:|.|.   .|..:..|:.|..||     |.:|:
Mouse    80 GTK--LHRPIMIGIGCVIMGLGCFLMSLPHFLMGRYE---YETTISPTSNLSSNSFLCMENRTQT 139

  Fly   186 MTACELNAMGEGQSENLTWTVWLFLAAQLLHGAGASPLFTLGVTYIDENVSKKMSSVYLGIYYTM 250
            :...:..|....:.::|.|.  ..|...::.|.|.:|:..||::||::....:.|.:|:||..:.
Mouse   140 LKPTQDPAECVKEMKSLMWI--YVLVGNIIRGIGETPIMPLGISYIEDFAKSENSPLYIGILESG 202

  Fly   251 ATVGPAIGYVFGGQLLLIYTDWMTVDPVQLSLTSDSKVWIGAWWLGFIFAAAMCLLIALPIFGYP 315
            ..:||.:|.:.|.....||.|..:|:...|::|.....|:||||:||:..|.:.:|.::|.|.:|
Mouse   203 KMIGPIVGLLLGSFCARIYVDTGSVNTDDLTITPTDTRWVGAWWIGFLVCAGVNILTSIPFFFFP 267

  Fly   316 KLLPGAEKLQ--LERV----SEAHATISEADDSSNVVRGLPRAVL----SLLANPTFFFLNLAGA 370
            |.|| .|.||  ::|.    .|.|...::.::     ||:.:..|    ||..||.:..|.|...
Mouse   268 KTLP-KEGLQDNVDRTENDKEEKHREKAKEEN-----RGITKDFLPFMKSLSCNPIYMLLILTSV 326

  Fly   371 TEGLVIAGFAAFLPKQIENQFSISPMYSALVMGLITVPAGGGGTFLGGYLVKKWNLACRGIIKMC 435
            .:.........||||.:|.|:..|.....|::|:..:|....|..|.|:::||:.:..:....|.
Mouse   327 LQINAFINMFTFLPKYLEQQYGKSTSEVVLLIGVCNLPPICIGYLLIGFIMKKFRITVKKAAYMA 391

  Fly   436 LLATTVAALFT-ICFLVSCPNPKFAGVTTGYK--MQPSSDSPALVASCNSNCGCSRTNYDPICGV 497
            ...:....|.: ..|::||.|.:.||:||.|:  ..|......::|.||:.|.|....:||:||.
Mouse   392 FCLSLFEYLLSYFHFMISCDNFQVAGLTTSYEGVQHPLYVENKVLADCNTRCSCLTNTWDPVCGD 456

  Fly   498 DGVMYYSPCYAGCVQEEHANSLKRYHNCSCIEQVGFVDDGNPSSEAPHFR--PDATNRKCDSTCQ 560
            :|:.|.|.|.|||.:.....:...:.|||||:     ..||.|:.....:  |:..|:
Mouse   457 NGLSYMSACLAGCEKSVGMGTHMVFQNCSCIQ-----SSGNSSAVLGLCKKGPECANK------- 509

  Fly   561 TLPLFVALCFILMVFTFLATMPALSATLRCVQDDQRSFALGLQWIKVRLLGTIPAPLIFGALIDE 625
             |..|:.:..|......:..:|.....|||::.:::|..:||.....|:...||||:.||||||.
Mouse   510 -LQYFLIMSVIGSFIYSITAIPGYMVLLRCIKSEEKSLGIGLHAFCTRIFAGIPAPIYFGALIDR 573

  Fly   626 SCILWQE-SCDKDAGGACLVY--DNFYISRYMWLLALICKLGS 665
            :|:.|.. .|.:.  |||.:|  :||   |.::|:......||
Mouse   574 TCLHWGTLKCGEP--GACRMYNINNF---RRIYLVLPAALRGS 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp26F	NP_609055.2	MFS_SLCO4_OATP4	64..589	CDD:340961	147/545 (27%)
Slco1a5	NP_570931.1	oat	1..625	CDD:273279	178/628 (28%)