Protein Alignment Oatp26F and slco5a1

DIOPT Version :10

• Sequence 1: NP_609055.2
• Gene: Oatp26F / 33927
• FlyBaseID: FBgn0051634
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: XP_002935370.3
• Gene: slco5a1 / 100492380
• XenbaseID: XB-GENE-480413
• Length: 879
• Species: Xenopus tropicalis
• Alignment Length: 656
• Identity: 222/656 - (33%)
• Similarity: 352/656 - (53%)
• Gaps: 73/656 - (11%)

  Fly    68 LFWLCWGGALQGLIVNGLINVSISTIERRFGLRSRQMGLVASGYDLASFACLVPVTYYGGRRGAS 132
            |..:|:...:|.|:|:|.::..|:|||||:.|:|.:.||:.|.:|:.|...:|.::|:||:  ..
 Frog   158 LVCMCFLTFIQSLMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGSLLVVVFISYFGGK--GR 220

  Fly   133 KPRFIAIGLIVMGMGSLVFLLPNFLVGNYRATIAEANVCETTGLPFNSNS----SQSMTACELNA 193
            :||::|||.:::.:|:.:|.||:|:...|:.....|:|. ..||..|.|:    |...:.|...:
 Frog   221 RPRWLAIGGLLIALGAALFSLPHFISPPYQIQELNASVA-NEGLCMNGNTTAKDSLESSMCPRES 284

  Fly   194 MGEGQSENLTWTVWLFLAAQLLHGAGASPLFTLGVTYIDENVSKKMSSVYLGIYYTMATVGPAIG 258
            .|:..|    ..|.||:.||:|.|.|::|::|||.||:|:||.|..:|:||.|.|.|..:|||.|
 Frog   285 GGKDHS----LYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKDNASLYLAIMYVMGALGPAAG 345

  Fly   259 YVFGGQLLLIYTDWMTVDPVQLSLTSDSKVWIGAWWLGFIFAAAMCLLIALPIFGYPKLLPGAEK 323
            |:.||.|:..|.|..::..::   .||.: :||.||.||:..|...||:..|:|.:||.||..::
 Frog   346 YLLGGVLIGFYVDPRSIIHIE---QSDPR-FIGNWWSGFLLCAMAMLLVIFPMFTFPKKLPPRQR 406

  Fly   324 LQLERVSEAHATISEAD----DSSNV----------------VRGLPRAVLSLLANPTFFFLNLA 368
            .:.::...::...||.|    .|||.                .:.||||.:.:|:|.||.|::|:
 Frog   407 KKKKKKGNSYDVSSEDDVLKEKSSNKSKADANPGPSIGFGKNFKDLPRAAVRILSNMTFLFVSLS 471

  Fly   369 GATEGLVIAGFAAFLPKQIENQFSISPMYSALVMGLITVPAGGGGTFLGGYLVKKWNLACRGIIK 433
            ...|..::..|..|:||.||:||.|....:::..|||.||:.|.|..||||::||..|..|...|
 Frog   472 YTAESAIVTAFITFIPKFIESQFGIPASSASIYTGLIIVPSAGVGIVLGGYIIKKLKLGARESAK 536

  Fly   434 MCLLATTVAAL-FTICFLVSCPNPKFAGVTTGYKMQP--SSDSPALVASCNSNCGCSRTNYDPIC 495
            :.::...|:.| |:..|:|.|.:....|:...|...|  :.....|...||.||||....|:|:|
 Frog   537 LAMICCGVSLLCFSTLFIVGCDSINLGGINIPYTTGPTLTMTHRNLTGGCNVNCGCKIHEYEPVC 601

  Fly   496 GVDGVMYYSPCYAGCVQ-EEHANSLKRYHNCSCIEQ--------VG------------FVDDGNP 539
            |.||:.|::||.||||. ..|:.:::.|..|.|::.        ||            ::::..
 Frog   602 GSDGITYFNPCLAGCVSVGNHSVAVRNYTECGCVQSRQVITPPTVGQRSQLRVVIVKTYLNENG- 665

  Fly   540 SSEAPHFRPDATNRKCDSTCQTLPLFVALCFILMVFTFLATMPALSATLRCVQDDQRSFALGLQW 604
                     .|.:.|||.||.||..|:...||:.:.|..|...|:..|||.|::.:|.||||:|:
 Frog   666 ---------YAVSGKCDRTCNTLIPFLIFLFIVTLITACAQPSAIIVTLRSVEEGERPFALGMQF 721

  Fly   605 IKVRLLGTIPAPLIFGALIDESCILWQESCDKDAGGACLVYDNFYISRYMWL-LALICKLGSVVF 668
            :.:|.|..||.|:.|||:||.:|:|||:.|  ...|:|..| |....|:::. ||...|....:|
 Frog   722 VLLRTLAYIPTPIYFGAVIDTTCMLWQQDC--GVQGSCWEY-NVTSFRFVYFGLAAGLKFLGFIF 783

  Fly   669 FACAWW 674
            ...||:
 Frog   784 IFLAWY 789

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp26F	NP_609055.2	MFS_SLCO4_OATP4	64..589	CDD:340961	187/568 (33%)
slco5a1	XP_002935370.3	MFS_SLCO5_OATP5	155..706	CDD:340962	187/568 (33%)