DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-iota and FCRL4

DIOPT Version :9

Sequence 1:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_112572.1	Gene:	FCRL4 / 83417	HGNCID:	18507	Length:	515	Species:	Homo sapiens

Alignment Length:	145	Identity:	38/145 - (26%)
Similarity:	60/145 - (41%)	Gaps:	18/145 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 QLKIRDVQESDRGWYMC-------QINTDPMKSQMGYLDVVVPPDIVDYQTS--QDVVRSTGQNV 152
            :|::..|...:.|.|.|       .|:......|:....:.|...:::.|.|  |.|   .|:.:
Human   245 ELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAV---EGEML 306

  Fly   153 TLTCS-ATGVPMPTITWRREEATPILISDDGDREVFSVEGQNLTLWQVQRSHMGAYLCIASNGVP 216
            .|.|| |.|....|.:|.||:....|    |.:...|:..: |.|..:::||.|.|.|.|.|...
Human   307 VLVCSVAEGTGDTTFSWHREDMQESL----GRKTQRSLRAE-LELPAIRQSHAGGYYCTADNSYG 366

  Fly   217 PTVSKRVMLVVNFAP 231
            |..|..:.:.|...|
Human   367 PVQSMVLNVTVRETP 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	7/34 (21%)
		Ig	39..122	CDD:299845	6/31 (19%)
		Ig	132..213	CDD:299845	25/83 (30%)
		IG_like	141..227	CDD:214653	27/88 (31%)
		IG_like	239..322	CDD:214653
		IGc2	245..313	CDD:197706
FCRL4	NP_112572.1	Ig1_FcgammaR_like	23..100	CDD:143229
		Ig2_FcgammaR_like	105..188	CDD:319307
		Ig_2	193..281	CDD:316418	7/35 (20%)
		IG_like	295..377	CDD:214653	27/89 (30%)
		ITIM motif 1	449..454
		ITIM motif 2	461..466
		ITIM motif 3	491..496
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	494..515
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000