DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-iota and opcml

DIOPT Version :9

Sequence 1:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_001072487.1	Gene:	opcml / 779942	XenbaseID:	XB-GENE-5831850	Length:	346	Species:	Xenopus tropicalis

Alignment Length:	320	Identity:	94/320 - (29%)
Similarity:	151/320 - (47%)	Gaps:	34/320 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LNNSDPKFSGPINNSTVPVGRDALLTCVVHDLVSFKVAWLRVDTQTILSIQNHVITKNHRISISH 90
            :.:.|..|...::|.||..|..|:|.|.|.:.|: :||||  :..|||...|...:.:.|:.:..
Frog    33 VRSGDAGFPKAMDNVTVRQGDSAILRCTVDNRVT-RVAWL--NRSTILYTGNDKWSIDPRVVLLA 94

  Fly    91 TEHRIWQLKIRDVQESDRGWYMCQINTD--PMKSQMGYLDVVVPPDIVDYQTSQDVVRSTGQNVT 153
            .....:.::|::|...|.|.|.|.:.||  |..|:: :|.|.|.|.|::  .|.|:..:.|..|.
Frog    95 NTKSQYSIEIQNVDIYDEGPYTCSVQTDNHPKTSRV-HLIVQVAPQILN--ISSDITVNEGSTVA 156

  Fly   154 LTCSATGVPMPTITWRR-EEATPILISDDGDREVFSVEGQNLTLWQVQRSHMGAYLCIASNGVPP 217
            |.|.|||.|.|.:|||. ...:...:|||   |...:.|       :.|...|.|.|.|:|.|..
Frog   157 LRCLATGRPEPAVTWRHFTGKSHRFVSDD---EYLEITG-------ITRDQSGQYECSAANDVSA 211

  Fly   218 TVSKRVMLVVNFAPTIWTRYDTIYVG--LGQKLTLECITESQPASVNFWLRDSQLLQGGSYESVS 280
            ...::|.:.||:.|.|   .||...|  ||||..|.|...:.|.:...|.|:...|..| .:.|.
Frog   212 PDIRKVRVTVNYPPYI---SDTRNTGASLGQKGILRCSASAVPLAEFQWYREETRLANG-LDGVR 272

  Fly   281 V---DHVFRIVMRITLRPITKRDFGEYICRAKNAMGQTDRIITVHHKAKKHGQHSHQTSS 337
            :   ||    :..:|...::::|:|.|.|.|.|.:|.::..:.::  |.....|:..:|:
Frog   273 IENKDH----MSILTFFNVSEKDYGNYTCVASNKLGNSNASVILY--AGPGAIHNRSSSA 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	28/87 (32%)
		Ig	39..122	CDD:299845	27/84 (32%)
		Ig	132..213	CDD:299845	26/81 (32%)
		IG_like	141..227	CDD:214653	27/86 (31%)
		IG_like	239..322	CDD:214653	24/87 (28%)
		IGc2	245..313	CDD:197706	20/70 (29%)
opcml	NP_001072487.1	Ig	46..134	CDD:325142	29/91 (32%)
		Ig_3	138..207	CDD:316449	26/80 (33%)
		ig	228..312	CDD:278476	25/88 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	58	1.000	Domainoid score	I10578
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	138	1.000	Inparanoid score	I4412
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.060