DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment DIP-iota and IGSF9

DIOPT Version :9

Sequence 1:NP_001097100.1 Gene:DIP-iota / 33925 FlyBaseID:FBgn0031837 Length:376 Species:Drosophila melanogaster
Sequence 2:NP_001128522.1 Gene:IGSF9 / 57549 HGNCID:18132 Length:1179 Species:Homo sapiens


Alignment Length:237 Identity:61/237 - (25%)
Similarity:100/237 - (42%) Gaps:44/237 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    98 LKIRDVQESDRGWYMCQI--------NTDPMKSQMGYLDVVVPPDIVDYQTSQDVVRSTG--QNV 152
            |:|..::..|:|||.|::        ..|.......:|.|..||   .:|.:...|....  :.|
Human    93 LQIEGLRVEDQGWYECRVFFLDQHIPEDDFANGSWVHLTV
NSPP---QFQETPPAVLEVQELEPV 154

  Fly   153 TLTCSATGVPMPTITWRREEATPILISDD---GDREVFSVEGQNLTLWQVQRSHMGAYLCIASNG 214
            ||.|.|.|.|:|.:||:       |...|   |..:| .|:...|.:.:|:|...|.|.|.||: 
Human   155 TLRCVARGSPLPHVTWK-------LRGKDLGQGQGQV-QVQNGTLRIRRVERGSSGVYTCQASS- 210

  Fly   215 VPPTVSKRVMLVVNFAPTIWTRYDTIYVGLGQKLTLECITESQPASVNF-WLRDSQLLQGGSYES 278
            ...:.:....|:|...|.|........|...|.::|.|..|:.||::.: |.:|          :
Human   211 TEGSATHATQLLV
LGPPVIVVPPKNSTVNASQDVSLACHAEAYPANLTYSWFQD----------N 265

  Fly   279 VSVDHVFRIVMRI------TLRPITKR--DFGEYICRAKNAM 312
            ::|.|:.|:..|:      :||.:..:  |.|.|.|...|.:
Human   266 INVFHISRLQPRVRILVDGSLRLLATQPDDAGCYTCVPSNGL 307

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-iotaNP_001097100.1 IG_like 39..125 CDD:214653 8/34 (24%)
Ig 39..122 CDD:299845 8/31 (26%)
Ig 132..213 CDD:299845 26/85 (31%)
IG_like 141..227 CDD:214653 25/90 (28%)
IG_like 239..322 CDD:214653 20/83 (24%)
IGc2 245..313 CDD:197706 19/77 (25%)
IGSF9NP_001128522.1 Ig 24..132 CDD:299845 9/38 (24%)
IG_like 28..110 CDD:214653 7/16 (44%)
I-set 136..223 CDD:254352 27/98 (28%)
Ig 154..220 CDD:143165 23/74 (31%)
Ig_3 226..305 CDD:290638 21/88 (24%)
IG_like 233..319 CDD:214653 20/85 (24%)
Ig 341..404 CDD:299845
IG_like 431..503 CDD:214653
Ig 436..500 CDD:143165
fn3 511..596 CDD:278470
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 606..626
FN3 625..715 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 767..919
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 940..988
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1015..1079
PDZ-binding. /evidence=ECO:0000250 1177..1179
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.