DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-iota and CG34353

DIOPT Version :9

Sequence 1:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_001287571.1	Gene:	CG34353 / 5740590	FlyBaseID:	FBgn0085382	Length:	581	Species:	Drosophila melanogaster

Alignment Length:	393	Identity:	104/393 - (26%)
Similarity:	173/393 - (44%)	Gaps:	62/393 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 RRLPS-----FWLLLLQSVCFSQASF-SELNNSDPKFSGPINNSTVPVGRDALLTCVVHDLVSFK 61
            ||:.|     |..:.:.|:.|...|. |.:..::|.|...........|...:|.|.|.:..::.
  Fly    52 RRVGSLPHILFLAIAVVSLHFESVSAQSMMTKNEPMFISRSETFKFITGETIVLPCEVANTDTYV 116

  Fly    62 VAWLRVDTQTILSIQNHVITKNHRISISHTEHRIWQLKIRDVQESDRGWYMCQINTDPMKSQMGY 126
            |||.|  ...||:..:..:|.:.|:.:.:.    :.|:|||...:|.|.|:|||.|...:.....
  Fly   117 VAWKR--GIAILTAGSVKVTPDPRVRLVNG----FNLQIRDALPTDAGDYICQIATMDPREITHT 175

  Fly   127 LDVVVPPDIVDYQTSQDVVRSTGQNVTLTCSATGVPMPTITWRREEATPILISDDGDREVFSVEG 191
            ::::|||.|....|...:....|.:|.:.|||||.|||.:||.|:..    |..:|:.::.|
  Fly   176 VEILVPPRIHHISTGGHLQVKKGSSVRIECSATGNPMPNVTWSRKNN----ILPNGEEKLHS--- 233

  Fly   192 QNLTLWQVQRSHMGAYLCIASNGVPPTVSKRVMLVVNFAPTIWTRYDTIYVGLGQKLTLECIT-- 254
            ..|::..|.|...|.|:|.|:|.|....|.:|:|.|.|:|.|......::.|.|.:.||.||.
  Fly   234 HVLSIENVDRHKGGVYICTANNRVGQPASSQVVLHVLFSPEISVERPVVFSGEGHEATLVCIVHG 298

  Fly   255 ESQPASVNFWLRDSQLLQGGSYESVSVDHVFRIVMR-------ITLRPITKRDFGEYICRAKNAM 312
            |:||..:  |.:|          ::.:|...|.:|.       :.:|.:..:|||.|.|.|:|.:
  Fly   299 ETQPEVI--WFKD----------TMQLDTTERHIMETRGSRHTLIIRKVHPQDFGNYSCVAENQL 351

  Fly   313 GQTDRIITVHHKAKKHGQHSHQTSSRESQFIV---------IEEY-------------IANMSDK 355
            |:..:.:.:..|......:|...|..:.::.:         ||||             :.|..|.
  Fly   352 GKARKTLQLSGKPNVAVFNSPPISQYKDRYNISWAVDSHSPIEEYKLSFRKLPQGHEVVGNAIDS 416

  Fly   356 SCS 358
            |.|
  Fly   417 SSS 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	23/85 (27%)
		Ig	39..122	CDD:299845	23/82 (28%)
		Ig	132..213	CDD:299845	27/80 (34%)
		IG_like	141..227	CDD:214653	28/85 (33%)
		IG_like	239..322	CDD:214653	23/91 (25%)
		IGc2	245..313	CDD:197706	21/76 (28%)
CG34353	NP_001287571.1	IG_like	100..180	CDD:214653	23/85 (27%)
		Ig	103..177	CDD:143165	22/79 (28%)
		IG_like	191..269	CDD:214653	28/84 (33%)
		IGc2	198..258	CDD:197706	24/66 (36%)
		I-set	273..360	CDD:254352	25/98 (26%)
		Ig	290..359	CDD:143165	21/80 (26%)
		FN3	<466..524	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
	3	2.810