DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-iota and paplna

DIOPT Version :9

Sequence 1:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	XP_005169942.1	Gene:	paplna / 562930	ZFINID:	ZDB-GENE-070815-4	Length:	1187	Species:	Danio rerio

Alignment Length:	331	Identity:	74/331 - (22%)
Similarity:	117/331 - (35%)	Gaps:	94/331 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 SQASFSELNNSD---PKFSGPINNSTVPV-----GRDALLTC------VVHDLVSFKVAWLRVDT 69
            :.|..||:::|.   .:.|...|....|:     |:.|.|.|      .:|   :..:.|.|..
Zfish   926 NNAGISEVDSSQSYTSQSSSRFNIDYSPLVEARAGQTAKLQCSVLPVSAIH---AVTIHWSRAG- 986

  Fly    70 QTILSIQNHVITKNHRISISHTEHRIWQLKIRDVQESDRGWYMCQINTDPMKSQ--------MGY 126
            |.:.|::             |::|....|.|:.:...|.|.|.|.: ||..|.:        :|.
Zfish   987 QPLNSLR-------------HSQHSDGTLVIKQLTADDSGLYTCTV-TDAQKFEERQVQLRVLGD 1037

  Fly   127 LDVVVPP---DIVDYQTSQDVVRSTGQNVTLTCSATGVPMPTITWRREEATPILISDDGDREVFS 188
            |.:...|   |:|...|:|.....||:||.:..|..|||               :..||.|...|
Zfish  1038 LRITKAPIDVDVVQGSTAQLACVVTGENVNVGWSRNGVP---------------VRPDGHRVHVS 1087

  Fly   189 VEGQNLTLWQVQRSHMGAYLCIASNGVPPTVSKRVMLVVNFAPTIWTRYDTIYVGLGQKLTLECI 253
            .:| .|.|..||....|.|.|.|..|   |:|......:..|.|.....|.     ||..:.:|:
Zfish  1088 ADG-TLILNNVQSVDEGTYTCNAYTG---TLSVSAAAEIRLAKTPQQDIDG-----GQFSSSDCV 1143

  Fly   254 TESQPASVNFWLRDSQLLQGGSYESVSVDHVFRIVMRITLRPITKRDFGEYICRAKNAMGQTDRI 318
            .:.:       |.:.:|:               :..|:...|     :....|.:..|...|||:
Zfish  1144 DQPE-------LANCKLI---------------VYARLCSSP-----YYSSFCCSSCARYATDRL 1181

  Fly   319 ITVHHK 324
            ...|.:
Zfish  1182 RRTHSR 1187

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	21/104 (20%)
		Ig	39..122	CDD:299845	20/93 (22%)
		Ig	132..213	CDD:299845	26/83 (31%)
		IG_like	141..227	CDD:214653	25/85 (29%)
		IG_like	239..322	CDD:214653	12/82 (15%)
		IGc2	245..313	CDD:197706	9/67 (13%)
paplna	XP_005169942.1	TSP1	24..75	CDD:214559
		ADAM_spacer1	181..293	CDD:310520
		TSP1	303..356	CDD:214559
		TSP1	388..442	CDD:214559
		TSP1	449..498	CDD:214559
		TSP1	504..557	CDD:214559
		KU	720..771	CDD:238057
		Ig_3	839..906	CDD:316449
		IGc2	960..1022	CDD:197706	18/79 (23%)
		I-set	1039..1121	CDD:333254	29/100 (29%)
		PLAC	1142..1173	CDD:312271	6/57 (11%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900