DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-iota and iglon5

DIOPT Version :9

Sequence 1:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_001017775.2	Gene:	iglon5 / 550472	ZFINID:	ZDB-GENE-050417-297	Length:	332	Species:	Danio rerio

Alignment Length:	299	Identity:	82/299 - (27%)
Similarity:	136/299 - (45%)	Gaps:	33/299 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 NNSTVPVGRDALLTCVVHDLVSFKVAWLRVDTQTILSIQNHVITKNHRISISHTEHRIWQLKIRD 102
            :|.||..|...:|.|.:.:.|:.| |||  :...||.......:.:.|:|:.:..:..:.::|..
Zfish    34 DNITVLEGESVVLRCKIDEEVTHK-AWL--NRSNILFTGTDKWSLDSRVSLENNNNSDFSIRIER 95

  Fly   103 VQESDRGWYMC--QINTDPMKSQMGYLDVVVPPDIVDYQTSQDVVRSTGQNVTLTCSATGVPMPT 165
            |..:|.|.|.|  |....|..:.: ||.|.||..||:  .|||...:.|::|.|.|.|.|.|.||
Zfish    96 VMVADEGPYTCSFQARNKPRTAHV-YLIVQVPARIVN--ISQDKSVNEGEDVNLFCLAVGRPEPT 157

  Fly   166 ITWRREEATPILISDDGDREVFSVEGQNLTLWQVQRSHMGAYLCIASNGVPPTVSKRVMLVVNFA 230
            |||:           |....:.: ||:.|.:.:::|.....:.||.:|||.|..:::|.:.||:.
Zfish   158 ITWK-----------DFKYGLLN-EGEFLEITEIKRHQAEDFECITNNGVAPPDTRKVKVTVNYP 210

  Fly   231 PTIWTRYDTIYVGLGQKLTLECITESQPASVNFWLRDSQLLQGGSYESVSVDHVFRIVMRIT--- 292
            |.| |....:...:|:...|.|...:.|.:...|.||.:       ..|..|:..:|....|
Zfish   211 PII-TDVKNMPAQVGKTAILRCEAMAVPTASFEWYRDDR-------RPVESDNTLKIKNEKTRSL 267

  Fly   293 --LRPITKRDFGEYICRAKNAMGQTDRIITVHHKAKKHG 329
              ...:|::.||.|.|.|.|.:|.::..:.:......:|
Zfish   268 LLFTNVTEKHFGNYTCFASNRLGASNASMLLFRPGAVYG 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	23/87 (26%)
		Ig	39..122	CDD:299845	23/84 (27%)
		Ig	132..213	CDD:299845	25/80 (31%)
		IG_like	141..227	CDD:214653	27/85 (32%)
		IG_like	239..322	CDD:214653	19/87 (22%)
		IGc2	245..313	CDD:197706	18/72 (25%)
iglon5	NP_001017775.2	IG_like	33..123	CDD:214653	25/92 (27%)
		Ig	35..123	CDD:299845	25/91 (27%)
		Ig	125..>183	CDD:299845	24/71 (34%)
		I-set	128..207	CDD:254352	29/92 (32%)
		IG_like	217..298	CDD:214653	19/87 (22%)
		ig	223..296	CDD:278476	19/79 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576338
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	1	1.000	-	-		otm26286
orthoMCL	1	0.900	-	-		OOG6_117834
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.750