DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment DIP-iota and Ntm

DIOPT Version :9

Sequence 1:NP_001097100.1 Gene:DIP-iota / 33925 FlyBaseID:FBgn0031837 Length:376 Species:Drosophila melanogaster
Sequence 2:XP_017451354.1 Gene:Ntm / 50864 RGDID:620958 Length:367 Species:Rattus norvegicus


Alignment Length:316 Identity:100/316 - (31%)
Similarity:157/316 - (49%) Gaps:26/316 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 WLLL--LQSVCFSQASFSELNNSDPKFSGPINNSTVPVGRDALLTCVVHDLVSFKVAWLRVDTQT 71
            |.:.  |.::|..|.  ..:.:.|..|...::|.||..|..|.|.|.:.:.|: :||||  :..|
  Rat    14 WAIFTGLAALCLFQG--VPVRSGDATFPKAMDNVTVRQGESATLRCTIDNRVT-RVAWL--NRST 73

  Fly    72 ILSIQNHVITKNHRISISHTEHRIWQLKIRDVQESDRGWYMCQINTD--PMKSQMGYLDVVVPPD 134
            ||...|.....:.|:.:.......:.::|::|...|.|.|.|.:.||  |..|:: :|.|.|.|.
  Rat    74 ILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRV-HLIVQVSPK 137

  Fly   135 IVDYQTSQDVVRSTGQNVTLTCSATGVPMPTITWRREEATPI-LISDDGDREVFSVEGQNLTLWQ 198
            ||  :.|.|:..:.|.|::|||.|||.|.||:|||......: .:|:|   |...::|       
  Rat   138 IV--EISSDISINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVSED---EYLEIQG------- 190

  Fly   199 VQRSHMGAYLCIASNGVPPTVSKRVMLVVNFAPTIWTRYDTIYVGLGQKLTLECITESQPASVNF 263
            :.|...|.|.|.|||.|...|.:||.:.||:.|.|.....| .|.:|||.||:|...:.|::...
  Rat   191 ITREQSGEYECSASNDVAAPVVRRVKVTVNYPPYISEAKGT-GVPVGQKGTLQCEASAVPSAEFQ 254

  Fly   264 WLRDSQLLQGGSYESVSVDHVFRIVMRITLRPITKRDFGEYICRAKNAMGQTDRII 319
            |.:|.:.|..|. :.|.|:: ...:.|:|...:::.|:|.|.|.|.|.:|.|:..|
  Rat   255 WFKDDKRLVEGK-KGVKVEN-RPFLSRLTFFNVSEHDYGNYTCVASNKLGHTNASI 308

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-iotaNP_001097100.1 IG_like 39..125 CDD:214653 27/87 (31%)
Ig 39..122 CDD:299845 26/84 (31%)
Ig 132..213 CDD:299845 28/81 (35%)
IG_like 141..227 CDD:214653 31/86 (36%)
IG_like 239..322 CDD:214653 26/81 (32%)
IGc2 245..313 CDD:197706 21/67 (31%)
NtmXP_017451354.1 Ig 44..132 CDD:416386 28/91 (31%)
Ig strand A' 44..49 CDD:409353 3/4 (75%)
Ig strand B 51..59 CDD:409353 3/7 (43%)
CDR1 59..63 CDD:409353 0/3 (0%)
FR2 64..70 CDD:409353 4/8 (50%)
Ig strand C 64..70 CDD:409353 4/8 (50%)
CDR2 71..83 CDD:409353 4/11 (36%)
Ig strand C' 72..76 CDD:409353 2/3 (67%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 7/33 (21%)
Ig strand D 87..94 CDD:409353 1/6 (17%)
Ig strand E 97..103 CDD:409353 0/5 (0%)
Ig strand F 110..118 CDD:409353 3/7 (43%)
CDR3 119..123 CDD:409353 2/3 (67%)
Ig strand G 123..132 CDD:409353 3/9 (33%)
FR4 125..132 CDD:409353 2/7 (29%)
Ig_3 136..205 CDD:404760 28/80 (35%)
Ig strand A' 144..148 CDD:409353 1/3 (33%)
Ig strand B 151..160 CDD:409353 4/8 (50%)
Ig strand F 197..205 CDD:409353 4/7 (57%)
Ig 223..307 CDD:416386 27/86 (31%)
putative Ig strand A 223..229 CDD:409353 2/5 (40%)
Ig strand B 239..243 CDD:409353 2/3 (67%)
Ig strand C 252..256 CDD:409353 0/3 (0%)
Ig strand E 278..282 CDD:409353 1/3 (33%)
Ig strand F 292..297 CDD:409353 2/4 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166337213
Domainoid 1 1.000 45 1.000 Domainoid score I11853
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 142 1.000 Inparanoid score I4382
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D265311at33208
OrthoFinder 1 1.000 - - FOG0000150
OrthoInspector 1 1.000 - - mtm8971
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X97
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
109.900

Return to query results.
Submit another query.