DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-iota and opcml

DIOPT Version :9

Sequence 1:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_001005580.1	Gene:	opcml / 449538	ZFINID:	ZDB-GENE-040927-3	Length:	342	Species:	Danio rerio

Alignment Length:	293	Identity:	89/293 - (30%)
Similarity:	146/293 - (49%)	Gaps:	20/293 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 NNSTVPVGRDALLTCVVHDLVSFKVAWLRVDTQTILSIQNHVITKNHRISISHTEHRIWQLKIRD 102
            :|.||..|..|:|.|.:.:.|| :||||  :..|||...|...:.:.|:.:.:|....:.:||.:
Zfish    40 DNITVRQGDSAVLKCSMDNKVS-RVAWL--NRTTILFTGNEKWSLDPRVVLLNTAVNEYSIKILN 101

  Fly   103 VQESDRGWYMCQI--NTDPMKSQMGYLDVVVPPDIVDYQTSQDVVRSTGQNVTLTCSATGVPMPT 165
            |...|.|.|:|.|  |..|..::: :|.|.||..||:..|  ||..:.|.||:|.|.|.|.|.|:
Zfish   102 VNLYDEGPYVCSILTNKKPESTKV-HLIVQVPARIVNVST--DVSVNEGSNVSLMCLAIGRPEPS 163

  Fly   166 ITWRREEATPILISDDGDREVFSVEGQNLTLWQVQRSHMGAYLCIASNGVPPTVSKRVMLVVNFA 230
            |.|:       ..|..|:|.|  .||:.:.:..:.:...|:|.||.||.:.|...:.|.:.||:.
Zfish   164 ILWK-------FRSSKGNRIV--TEGEYVEMTGITKDMSGSYDCITSNDISPPDVRTVQVTVNYP 219

  Fly   231 PTIWTRYDTIYVGLGQKLTLECITESQPASVNFWLRDSQLLQGGSYESVSVDHVFRIVMRITLRP 295
            |.| :|..:....:|||..|.|...:.|.:...|.:..:.:..| :..|.:::..:..| :|...
Zfish   220 PVI-SRARSTGTAVGQKGVLWCEASAVPLADFQWFKGERRILNG-FNGVKIENKGKQSM-LTFFN 281

  Fly   296 ITKRDFGEYICRAKNAMGQTDRIITVHHKAKKH 328
            :::.|:|.|.|.|.|.:|.|:..|.::.....|
Zfish   282 VSEEDYGNYTCVAINTLGITNASIILYGPGAIH 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	29/87 (33%)
		Ig	39..122	CDD:299845	29/84 (35%)
		Ig	132..213	CDD:299845	27/80 (34%)
		IG_like	141..227	CDD:214653	27/85 (32%)
		IG_like	239..322	CDD:214653	20/82 (24%)
		IGc2	245..313	CDD:197706	17/67 (25%)
opcml	NP_001005580.1	Ig	41..129	CDD:299845	30/91 (33%)
		IG_like	41..129	CDD:214653	30/91 (33%)
		IG_like	139..216	CDD:214653	28/87 (32%)
		IGc2	146..202	CDD:197706	21/64 (33%)
		I-set	219..307	CDD:254352	23/90 (26%)
		ig	223..307	CDD:278476	21/85 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576343
Domainoid	1	1.000	64	1.000	Domainoid score	I10104
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	128	1.000	Inparanoid score	I4644
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	1	1.000	-	-		otm26286
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.800