DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-iota and DIP-gamma

DIOPT Version :9

Sequence 1:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_651649.1	Gene:	DIP-gamma / 43417	FlyBaseID:	FBgn0039617	Length:	413	Species:	Drosophila melanogaster

Alignment Length:	400	Identity:	153/400 - (38%)
Similarity:	221/400 - (55%)	Gaps:	33/400 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 FWLLLLQSVCFSQASFSELNNS------DPKFSGPINNSTVPVGRDALLTCVVHDLVSFKVAWLR 66
            |.:|::.:.|.|.::.::.:.|      ||:|.|.|||.|.|.||:|:|.|.|.:|...||.|||
  Fly    10 FVILIMATKCGSGSTQNQHHESSSQLDPDPEFIGFINNVTYPAGREAILACSVRNLGKNKVGWLR 74

  Fly    67 VDTQTILSIQNHVITKNHRISISHTEHRIWQLKIRDVQESDRGWYMCQINTDPMKSQMGYLDVVV 131
            ...||:|::|..|:|.|.|||:.|.:...|:|||..::|||||.|||||||.|||.|:|.:||.|
  Fly    75 ASDQTVLALQGRVVTHNARISVMHQDMHTWKLKISKLRESDRGCYMCQINTSPMKKQVGCIDVQV 139

  Fly   132 PPDIVDYQTSQDVVRSTGQNVTLTCSATGVPMPTITWRREEATPILISDDGDREVFSVE---GQN 193
            ||||::.::|.|:....|::.||||.|||.|.|.:|||||:...|||...|.||:..||   |.:
  Fly   140 PPDIINEESSADLAVQEGEDATLTCKATGNPQPRVTWRREDGEMILIRKPGSRELMKVESYNGSS 204

  Fly   194 LTLWQVQRSHMGAYLCIASNGVPPTVSKRVMLVVNFAPTIWTRYDTIYVGLGQKLTLECITESQP 258
            |.|.:::|..||||||||||.|||.|||||.|.|.|||.:......:...||..:.|||..|:.|
  Fly   205 LRLLRLERRQMGAYLCIASNDVPPAVSKRVSLSVQFAPMVRAPSQLLGTPLGSDVQLECQVEASP 269

  Fly   259 ASVNFWLRDSQ----------------------LLQGGSYESVSVDHVFRIVMRITLRPITKRDF 301
            :.|::||:.::                      ||.|..|........:|.||.:.:|..:..|.
  Fly   270 SPVSYWLKGARTSNGFASVSTASLESGSPGPEMLLDGPKYGITERRDGYRGVMLLVVRSFSPSDV 334

  Fly   302 GEYICRAKNAMGQTDRIITVHHKAKKHGQHSHQTSSRESQFIVIEEYIANMS-DKSCSFQPLWIM 365
            |.|.|.:.|::|:.:..:.: ::.|.|...|.......:....:||...|.. ....::|||..|
  Fly   335 GTYHCVSTNSLGRAEGTLRL-YEIKLHPGASASNDDHLNYIGGLEEAARNAGRSNRTTWQPLLAM 398

  Fly   366 FLCFVNKVSL 375
            .:....::||
  Fly   399 LMLLWMRLSL 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	46/85 (54%)
		Ig	39..122	CDD:299845	44/82 (54%)
		Ig	132..213	CDD:299845	41/83 (49%)
		IG_like	141..227	CDD:214653	48/88 (55%)
		IG_like	239..322	CDD:214653	24/104 (23%)
		IGc2	245..313	CDD:197706	22/89 (25%)
DIP-gamma	NP_651649.1	IG_like	47..139	CDD:214653	49/91 (54%)
		Ig	47..129	CDD:299845	43/81 (53%)
		Ig	140..238	CDD:299845	52/97 (54%)
		IG_like	247..355	CDD:214653	24/108 (22%)
		Ig	256..351	CDD:299845	23/94 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	64	1.000	Domainoid score	I10104
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	128	1.000	Inparanoid score	I4644
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D102261at50557
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	1	1.000	-	-		mtm8732
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
	8	7.870