DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-iota and klg

DIOPT Version :9

Sequence 1:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_524454.2	Gene:	klg / 42707	FlyBaseID:	FBgn0017590	Length:	545	Species:	Drosophila melanogaster

Alignment Length:	309	Identity:	87/309 - (28%)
Similarity:	147/309 - (47%)	Gaps:	28/309 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LQSVCFSQASFSELNNSDPKFSGPINNSTVPVGRDALLTCVVHDLVSFKVAWLRVDTQTILSIQN 77
            :.:|..|..:.|.|..:.|:|....:.....||...:|.|.|.:|.:|.:.|.|  ...:|:..|
  Fly    83 MSNVQQSAVAASTLTATLPRFLSRGHTYRAVVGDTLVLPCQVENLGNFVLLWRR--GTNVLTASN 145

  Fly    78 HVITKNHRISISHTEHRIWQLKIRDVQESDRGWYMCQINTDPMKSQMGYLDVVVPPDIVDYQTSQ 142
            .::|::.|:.:...    :.|:|.|::..|.|.|:|||:....:.|:..::::|||.:....||.
  Fly   146 IMVTRDERVRLIDG----YNLEISDLEPQDAGDYVCQISDKINRDQVHTVEILVPPSVRAIPTSG 206

  Fly   143 DVVRSTGQNVTLTCSATGVPMPTITWRREEATPILISDDGDREVFSVEGQNLTLWQVQRSHMGAY 207
            .:....|..:||.|..:|.|:|:|.|.::.......:..||       |..|||.:::|...|.|
  Fly   207 QLQARKGGPITLECKGSGNPVPSIYWTKKSGANKSTARIGD-------GPILTLEKLERQQAGVY 264

  Fly   208 LCIASNGVPPTVSKRVMLVVNFAPTIWTRYDTIYVGLGQKLTLECITESQPASVNFWLRDSQLLQ 272
            .|.|.|||...|:..:.|.|.:.|.|......|:.|.|.:..|.||..:.|.:...|.::|..:|
  Fly   265 QCTADNGVGDPVTVDMRLDVLYPPDIQVEKSWIHSGEGFEAKLVCIVFADPVATVSWYQNSFPIQ 329

  Fly   273 GGSYESVSVDHVFRIVM------RITLRPITKRDFGEYICRAKNAMGQT 315
                   |.|.  ||:.      .:|:|.|.:.|||.|.|.|.|::|::
  Fly   330 -------STDR--RIMATRANRHMLTIRHIQQEDFGNYSCVADNSLGRS 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	23/85 (27%)
		Ig	39..122	CDD:299845	22/82 (27%)
		Ig	132..213	CDD:299845	24/80 (30%)
		IG_like	141..227	CDD:214653	26/85 (31%)
		IG_like	239..322	CDD:214653	25/83 (30%)
		IGc2	245..313	CDD:197706	22/73 (30%)
klg	NP_524454.2	DUF1370	63..>124	CDD:284518	10/40 (25%)
		IG_like	109..195	CDD:214653	23/91 (25%)
		Ig	118..191	CDD:143165	21/78 (27%)
		IG_like	205..274	CDD:214653	24/75 (32%)
		IGc2	213..273	CDD:197706	22/66 (33%)
		IGc2	301..367	CDD:197706	22/74 (30%)
		FN3	392..486	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442860
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
	4	3.740