DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-iota and kirrel1a

DIOPT Version :9

Sequence 1:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_001349348.1	Gene:	kirrel1a / 405804	ZFINID:	ZDB-GENE-040426-2126	Length:	819	Species:	Danio rerio

Alignment Length:	350	Identity:	82/350 - (23%)
Similarity:	146/350 - (41%)	Gaps:	86/350 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLLLQSVCFSQASFSELNNSDPKFSGPINNSTVPVGRDALLTCVVHDLVSFKVAWLRVDTQTILS 74
            ||||.|:..   ||..:..:  :||....:.:|.:|:..:|:|||.: .|..|.|    |:..|:
Zfish     4 LLLLLSLAL---SFHRVRTA--RFSQEPADQSVVLGQRVVLSCVVFN-YSGIVQW----TKDGLA 58

  Fly    75 IQNHVITKNHRISISHTEHRI--------WQLKIRDVQESDRGWYMCQINTDPMKSQMGYLDVVV 131
            :.   |.::.|   :...:|:        :.|:|...:.||...|.||.....::|:...|.|::
Zfish    59 LG---IGEDLR---AWPRYRVLRLVDVGQYNLEISAAELSDDSLYECQATEAALRSRRAKLTVLI 117

  Fly   132 PPDIVDYQTSQDVVRSTGQNVTLTCSATGV-PMPTITWRRE--------EATPILISDDGDREVF 187
            |||....:.|.:::.:.|....::|.:.|. |...|.|:::        ..|.:|    .||:..
Zfish   118 PPDEPVIEGSPEILLTAGVPYNMSCVSRGAKPASVIEWQKDGLPIEGAVSTTEVL----PDRKRV 178

  Fly   188 SVE------------GQNLTLWQVQRSHMGAYLCIASN-GVPPTVSKRVMLVVNFAPTIWTRYDT 239
            :..            |:|.|             |:|:| .||......:.|.|:..|.:....:.
Zfish   179 TTRSYLPIQPLDTDTGKNFT-------------CVATNLAVPMGKRATITLNVHHPPVVTLSIEP 230

  Fly   240 IYVGLGQKLTLECITESQPASVNF-WLRDSQLLQGGSYESVSV---DHVFRIVMRITLRPITKRD 300
            ..|..|:::|..|...:.|..:.: |.:...::| |:.|||.|   ||.|
Zfish   231 RSVLEGERVTFTCQATANPPIMGYKWAKGGVVIQ-GARESVFVTKADHSF--------------- 279

  Fly   301 FGEYI-CRAKNAMGQTD--RIITVH 322
            |.|.: |:..||:|.|:  .::.||
Zfish   280 FTEPVSCQVFNAVGSTNVSILVDVH 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	22/93 (24%)
		Ig	39..122	CDD:299845	21/90 (23%)
		Ig	132..213	CDD:299845	19/101 (19%)
		IG_like	141..227	CDD:214653	20/107 (19%)
		IG_like	239..322	CDD:214653	22/89 (25%)
		IGc2	245..313	CDD:197706	19/72 (26%)
kirrel1a	NP_001349348.1	I-set	21..115	CDD:333254	25/104 (24%)
		Ig2_KIRREL3-like	137..218	CDD:143236	18/97 (19%)
		I-set	222..303	CDD:333254	23/96 (24%)
		Ig_3	307..372	CDD:316449
		Ig5_KIRREL3	390..493	CDD:143306
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910