DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-iota and ImpL2

DIOPT Version :9

Sequence 1:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_728961.2	Gene:	ImpL2 / 38513	FlyBaseID:	FBgn0001257	Length:	267	Species:	Drosophila melanogaster

Alignment Length:	199	Identity:	44/199 - (22%)
Similarity:	75/199 - (37%)	Gaps:	46/199 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 RSTGQNVTLTCSATGVPMPTITW-----RREEATPILISDDGDREVFSVEGQNLTLWQVQRSHM- 204
            ::.|..:.:.|...|..:|:|.|     .|.|.      ||.|....:.|..: .:.:|:.||:
  Fly    70 QADGATIEIVCEMMGSQVPSIQWVVGHLPRSEL------DDLDSNQVAEEAPS-AIVRVRSSHII 127

  Fly   205 -------GAYLCI---------ASNGVPPTVSKRVMLVVNF----APTIWTRYDTIYVGLGQKLT 249
                   ..|.|:         ||..|.|..|.|:.....:    .|.|.....|....:|..:.
  Fly   128 DHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQ 192

  Fly   250 LECITESQPASVNFWL--RDSQLLQGGSYESVSVDHVFRIVMR--ITLRPITKRDFGEYICRAKN 310
            |.|...::|.:...||  .:.:::||         |..|::..  :.:..|...|.|.|.|.|:|
  Fly   193 LPCRVHARPRAEITWLNNENKEIVQG---------HRHRVLANGDLLISEIKWEDMGNYKCIARN 248

  Fly   311 AMGQ 314
            .:|:
  Fly   249 VVGK 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653
		Ig	39..122	CDD:299845
		Ig	132..213	CDD:299845	18/88 (20%)
		IG_like	141..227	CDD:214653	23/102 (23%)
		IG_like	239..322	CDD:214653	19/80 (24%)
		IGc2	245..313	CDD:197706	17/71 (24%)
ImpL2	NP_728961.2	IGc2	187..251	CDD:197706	17/72 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900