DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-iota and CG13506

DIOPT Version :9

Sequence 1:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_001286718.1	Gene:	CG13506 / 37556	FlyBaseID:	FBgn0034723	Length:	503	Species:	Drosophila melanogaster

Alignment Length:	329	Identity:	71/329 - (21%)
Similarity:	128/329 - (38%)	Gaps:	79/329 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 GRDALLTCVVHDLVSFKVAWLRVDTQTILSIQNHVITKNHRISISHTEHRIWQ---------LKI 100
            |.|.:|.|   |..:|:             :.|.|:...:||.|::.::.|.|         :.:
  Fly    84 GDDVILNC---DARNFQ-------------LSNAVVWYKNRIIIANGQNPISQRVQCMLNNSILL 132

  Fly   101 RDVQESDRGWYMCQINTDPMKSQMGYLDVVVPPDIVDYQTSQDVVRSTGQNVTLTCSATGVPMPT 165
            |:|...|...|.|                    :|:..:..|......|..:::.|....:...:
  Fly   133 RNVSPEDSDDYYC--------------------EILPQRVRQHTALRVGARLSILCDDRDITDRS 177

  Fly   166 ITWRR-------------EEATPILISDDGDREVFSVEGQN--LTLWQVQRSHMGAYLCIASNGV 215
            .|:|:             :.||.....:|.:.:..||:.||  :.|..|...:.|.|.|:|.:|.
  Fly   178 QTFRQGDHHKLECRTYLPDNATIKWSFNDLNGQPSSVDNQNGVIILDNVDEKNAGDYQCLADDGS 242

  Fly   216 PPTVSKRVMLVVNFAPTIWTRYDTIYVGLGQKLTLECITESQPASVNFWLRDSQLLQ-GGSY--- 276
            .......|.:.|.::|.:.|....:....|....|.|...::|...:::::|.:.|| ...|
  Fly   243 RHPPHGTVHIDVQYSPIVSTHRHNVNTEKGATAELYCNYRAKPIGRSYFIKDGKTLQLSDKYSLK 307

  Fly   277 ESVSVDHVFRIVMRITL--RPITKRDFGEYICRAKNAMGQTDRIITVHHKAKKHGQHSHQTSSRE 339
            :||..||     .|.||  |.:|..|.|||:|:.:||:|.        ::.|.|..::.:|...|
  Fly   308 DSVHNDH-----NRTTLIVREVTDSDLGEYLCQVENAIGS--------NEVKVHVSYNPETPQFE 359

  Fly   340 SQFI 343
            ...:
  Fly   360 DMTV 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	18/88 (20%)
		Ig	39..122	CDD:299845	18/85 (21%)
		Ig	132..213	CDD:299845	19/95 (20%)
		IG_like	141..227	CDD:214653	20/100 (20%)
		IG_like	239..322	CDD:214653	25/88 (28%)
		IGc2	245..313	CDD:197706	24/73 (33%)
CG13506	NP_001286718.1	IG_like	79..146	CDD:214653	18/97 (19%)
		IGc2	83..146	CDD:197706	18/97 (19%)
		IG_like	176..254	CDD:214653	17/77 (22%)
		Ig	176..239	CDD:299845	14/62 (23%)
		I-set	258..349	CDD:254352	28/103 (27%)
		Ig	275..348	CDD:143165	25/85 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442857
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740