DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-iota and wrapper

DIOPT Version :9

Sequence 1:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_477404.1	Gene:	wrapper / 37555	FlyBaseID:	FBgn0025878	Length:	500	Species:	Drosophila melanogaster

Alignment Length:	313	Identity:	86/313 - (27%)
Similarity:	131/313 - (41%)	Gaps:	56/313 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 SELNNSDPKFSGP-----INNSTVPVGRDALLTCVVHDLVSFKVAWLRVDTQTILSIQNHVITKN 83
            ::|.||....|.|     ..|.||.      |.|.::....: |.|.| |...::..::..:...
  Fly    29 NDLENSQKFKSIPTTVKTYENDTVQ------LPCTLNTPFRY-VRWHR-DDVALVDSRHPELPPP 85

  Fly    84 HRISISHTEHRIW---QLKIRDVQESDRGWYMCQINTD--------PMKSQMGYLDVVVPPDIVD 137
            .||       .:|   .|::.:||.||.|.|.|::|:|        .::.|:....::.|.|:
  Fly    86 DRI-------MLWPNGSLQVANVQSSDTGDYYCEMNSDSGHVVQQHAIEVQLAPQVLIEPSDL-- 141

  Fly   138 YQTSQDVVRSTGQNVTLTCSATGVPMPTITWRREEATPILISDDGDREVFSVEGQNLTLWQVQRS 202
              |.|.:    |....:.|.|.|||.|.||||.........|:.|:|       |:|.|....|:
  Fly   142 --TEQRI----GAIFEVVCEAQGVPQPVITWRLNGNVIQPQSNTGNR-------QSLILEIKSRN 193

  Fly   203 HMGAYLCIASNGVPPTVSKRVMLVVNFAPTIWTRYDTIYVGLGQKLTLECITESQPASVNFWLRD 267
            ..|...|:|||||.......|.|.|.|:|.:......:|..||.:..||||.|:.||:...|...
  Fly   194 QAGLIECVASNGVGEPAVANVYLHVLFSPEVSIPQPVVYTKLGSRAHLECIVEAAPAATVKWFHH 258

  Fly   268 SQLLQGGSYESV---------SVDHVFRIVMR-ITLRPITKRDFGEYICRAKN 310
            ...:..|::.:.         ||||....|.. :.::.:...|.|:|.|||.|
  Fly   259 GLPVALGAHSTTHESELQTNRSVDHYVNAVRHMLVVKSVRNADMGQYECRASN 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	23/96 (24%)
		Ig	39..122	CDD:299845	22/93 (24%)
		Ig	132..213	CDD:299845	25/80 (31%)
		IG_like	141..227	CDD:214653	28/85 (33%)
		IG_like	239..322	CDD:214653	24/82 (29%)
		IGc2	245..313	CDD:197706	22/76 (29%)
wrapper	NP_477404.1	Ig	41..124	CDD:299845	23/97 (24%)
		IG_like	41..118	CDD:214653	23/91 (25%)
		IG_like	145..218	CDD:214653	27/83 (33%)
		Ig	147..219	CDD:299845	27/78 (35%)
		I-set	224..323	CDD:254352	24/88 (27%)
		IGc2	236..314	CDD:197706	22/76 (29%)
		FN3	339..431	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810