DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-iota and Igsf9b

DIOPT Version :9

Sequence 1:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_001363879.1	Gene:	Igsf9b / 315510	RGDID:	1564717	Length:	1441	Species:	Rattus norvegicus

Alignment Length:	354	Identity:	83/354 - (23%)
Similarity:	145/354 - (40%)	Gaps:	66/354 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 WLL--LLQSVCFSQASFSELNN---SDPKFSGPINNSTVPVGRDALLTC-VVHDLVS----FKVA 63
            |.:  |:.||..::...:::.:   .:|:|      .|...|...:|.| |:|.:..    :.|.
  Rat     3 WYVATLIASVISTRGLVAQVAHGLREEPEF------VTARAGEGVVLRCDVIHPVTGQPPPYVVE 61

  Fly    64 WLRVDTQTILSIQ-----NHVITK-NHRISISHTEHRIWQLKIRDVQESDRGWYMCQI-----NT 117
            |.:......:.|:     .||..: ..|.|:    |....|::..|:..|:|||.|::     ..
  Rat    62 WFKFGVPIPIFIKFGYYPPHVDPEYAGRASL----HDKASLRLEQVRSEDQGWYECKVLMLDQQY 122

  Fly   118 DPM-KSQMGYLDVVVPPDIVDYQTSQDVVRSTGQNVTLTCSATGVPMPTITWRREEATPILISDD 181
            |.. .....:|.:..||...: ...|.:....|.::|:||:|.|.|.|.:||.:|..   |:|..
  Rat   123 DTFHNGSWVHLTINAPPTFTE-TPPQYIEAKEGGSITMTCTAFGNPKPIVTWLKEGT---LLSAS 183

  Fly   182 GDREVFSVEGQNLTLWQVQRSHMGAYLC----IASNGVPPTVSKRVMLVVNFAPTIWTRYDTIYV 242
            |.   :.|...:||:..|.|...|||.|    |....|..|     .|:|...|.|.:..:.|.|
  Rat   184 GK---YQVSDGSLTVTSVSREDRGAYTCRAYSIQGEAVHTT-----HLLVQGPPFIVSPPENITV 240

  Fly   243 GLGQKLTLECITESQPASVNF-WLRDSQLLQGGSYESVSVDHVFRIVMRITLR------PITKRD 300
            .:.|...|.|..|:.|.::.: |....        |:|...:..::.:||.:.      .:...|
  Rat   241 NISQDALLTCRAEAYPGNLTYTWYWQD--------ENVYFQNDLKLRVRILIDGTLIIFRVKPED 297

  Fly   301 FGEYICRAKNAMGQT---DRIITVHHKAK 326
            .|:|.|...|::|::   ...:||.:.|:
  Rat   298 AGKYTCVPSNSLGRSPSASAYLTVQYPAR 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	22/102 (22%)
		Ig	39..122	CDD:299845	22/99 (22%)
		Ig	132..213	CDD:299845	27/84 (32%)
		IG_like	141..227	CDD:214653	28/89 (31%)
		IG_like	239..322	CDD:214653	19/92 (21%)
		IGc2	245..313	CDD:197706	15/74 (20%)
Igsf9b	NP_001363879.1	PHA03247	<898..1246	CDD:223021
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	918..1044
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1111..1332
		Ig	41..115	CDD:319273	19/77 (25%)
		I-set	139..225	CDD:369462	29/97 (30%)
		Ig	229..321	CDD:386229	20/99 (20%)
		Ig	<353..414	CDD:386229
		Ig	438..502	CDD:319273
		FN3	510..605	CDD:238020
		FN3	621..703	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	762..821
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810