DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-iota and Fcgr3a

DIOPT Version :9

Sequence 1:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_997486.2	Gene:	Fcgr3a / 304966	RGDID:	1303067	Length:	249	Species:	Rattus norvegicus

Alignment Length:	220	Identity:	45/220 - (20%)
Similarity:	76/220 - (34%)	Gaps:	54/220 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 WLLLLQSVCFSQASFSELNNSDPKFSGPINNSTVPVGRDALLTCVVHDLVSFKVAWLRV--DTQT 71
            |.|||.:......|           ||        ||.......|:.|     ..|:||  :...
  Rat     2 WYLLLPTALLLTVS-----------SG--------VGAGLQKAVVILD-----PEWVRVLEEDCV 42

  Fly    72 ILSIQNHVITKNHRISISHTE----HRIWQLKIRDVQESDRGWYMCQIN----TDPMKSQMGYLD 128
            ||..|.....:::.....|.:    |:.....|:..:..|.|.|.||..    :||::     ||
  Rat    43 ILRCQGTFSPEDNSTKWFHNKSLISHQDANYVIQSARVKDSGMYRCQTAFSALSDPVQ-----LD 102

  Fly   129 VVVPPDIVDYQTSQDVVRSTGQNVTLTCSATGVPMPTITWRREEATPILISDDGDREVFSVEGQN 193
              |..|.:..||::.:.:. |..:.|.|.         :||......:....:|..:.:......
  Rat   103 --VHADWLLLQTTKRLFQE-GDPIRLRCH---------SWRNTPVFKVTYLQNGKGKKYFHRNSE 155

  Fly   194 LTLWQVQRSHMGAYLC---IASNGV 215
            |::.:...:..|:|.|   |..|.:
  Rat   156 LSISKATHADSGSYFCRGIIGRNNI 180

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	20/95 (21%)
		Ig	39..122	CDD:299845	20/92 (22%)
		Ig	132..213	CDD:299845	14/83 (17%)
		IG_like	141..227	CDD:214653	12/78 (15%)
		IG_like	239..322	CDD:214653
		IGc2	245..313	CDD:197706
Fcgr3a	NP_997486.2	Ig1_FcgammaR_like	25..103	CDD:409410	20/89 (22%)
		Ig strand B	42..46	CDD:409410	2/3 (67%)
		Ig strand C	56..60	CDD:409410	0/3 (0%)
		Ig strand E	71..75	CDD:409410	0/3 (0%)
		Ig strand F	85..90	CDD:409410	2/4 (50%)
		Ig strand G	96..99	CDD:409410	1/2 (50%)
		Ig2_FcgammaR_like	107..189	CDD:409411	14/84 (17%)
		Ig strand B	123..127	CDD:409411	1/3 (33%)
		Ig strand C	137..141	CDD:409411	0/3 (0%)
		Ig strand E	154..158	CDD:409411	1/3 (33%)
		Ig strand F	168..173	CDD:409411	2/4 (50%)
		Ig strand G	182..185	CDD:409411
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000