DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-iota and ncam1a

DIOPT Version :9

Sequence 1:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	XP_009293555.1	Gene:	ncam1a / 30447	ZFINID:	ZDB-GENE-990415-31	Length:	1010	Species:	Danio rerio

Alignment Length:	327	Identity:	84/327 - (25%)
Similarity:	134/327 - (40%)	Gaps:	64/327 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 NSTVPVGRDALLTCVVHDLVSFKVAWLRVDTQTILSIQNHVITKNHRISISHTEHRIWQLKIRDV 103
            |:|..:.:...|.|.........|.|.|.:|:         :..:.:.|::....   :|.|:||
Zfish   219 NATADINQAVTLACHADGYPEPTVKWARGNTE---------LESDEKYSLNEDGS---ELTIKDV 271

  Fly   104 QESDRGWYMC-QINTDPMKSQMGYLDVVVPPDI--VDYQTSQDVVRSTGQNVTLTCSATGVPMPT 165
            .:.|.|.|.| ..|....:|:...|:|.|.|.|  ::.||:.::    .:.:||||.|||.|.|.
Zfish   272 NKLDEGDYKCIARNKAGERSEEVTLNVFVQPKITFLENQTASEL----EEQITLTCEATGDPTPN 332

  Fly   166 I---------------TWRREEATPILISDDGDREVFS-VEGQNLTLWQVQRSHMGAYLCIASNG 214
            |               :|.|.|....|   ||:..|.| ....:|||..||.:..|.|||.|.|.
Zfish   333 IIWSFGRRVFTENEQASWTRPEKHKSL---DGNVVVRSDARVSSLTLKYVQFTDAGQYLCTARNS 394

  Fly   215 VPPTVSKRVMLVVNFAPTIWTRYDTIYVGLGQKLTLECITESQPASVNFWLRDSQLLQGGSYESV 279
            :...: :.:.|.|.:||.| .....::...|....:.|...:.|.:...|.||.|.|...:..:|
Zfish   395 IGQDI-QSMYLEVRYAPKI-QGPQAVFTWEGNPANITCEALAHPGASVLWFRDGQQLPSANTTNV 457

  Fly   280 SVDHVFRIVMRITLRPITKRDFGEYICRAKNAMGQTDRIITVHHKAKKHGQHSHQTSSRESQFIV 344
            .:.:. ..|..:.:.|.::.|||.|.|.|.|.:|                     |.|:|  ||:
Zfish   458 KIYNT-PTVSFLEVTPDSQNDFGSYNCTATNVIG---------------------TESKE--FIL 498

  Fly   345 IE 346
            ::
Zfish   499 VQ 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	19/86 (22%)
		Ig	39..122	CDD:299845	18/83 (22%)
		Ig	132..213	CDD:299845	32/98 (33%)
		IG_like	141..227	CDD:214653	30/101 (30%)
		IG_like	239..322	CDD:214653	19/82 (23%)
		IGc2	245..313	CDD:197706	18/67 (27%)
ncam1a	XP_009293555.1	Ig	20..112	CDD:299845
		I-set	21..111	CDD:254352
		IG_like	121..200	CDD:214653
		IGc2	128..189	CDD:197706
		Ig	208..301	CDD:299845	21/93 (23%)
		IG_like	219..298	CDD:214653	20/90 (22%)
		Ig	300..406	CDD:299845	35/113 (31%)
		IG_like	308..406	CDD:214653	32/105 (30%)
		ig	413..498	CDD:278476	23/108 (21%)
		IG_like	415..498	CDD:214653	23/106 (22%)
		fn3	505..589	CDD:278470
		FN3	624..715	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810