DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-iota and Lsamp

DIOPT Version :9

Sequence 1:NP_001097100.1 Gene:DIP-iota / 33925 FlyBaseID:FBgn0031837 Length:376 Species:Drosophila melanogaster
Sequence 2:XP_038944182.1 Gene:Lsamp / 29561 RGDID:71102 Length:378 Species:Rattus norvegicus


Alignment Length:422 Identity:118/422 - (27%)
Similarity:170/422 - (40%) Gaps:104/422 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 LPSFWLL-------LLQSVCFSQASFSELNNSDPKFSG-PI---------NNSTVPVGRDALLTC 52
            |.|.|:|       .||.:.|.....:|:|.|.....| |:         :|.||..|..|:|.|
  Rat     6 LHSVWVLGFFLSLFSLQVLAFWNQPPAEVNLSPITIPGLPVRSVDFNRGTDNITVRQGDTAILRC 70

  Fly    53 VVHDLVSFKVAWLRVDTQTILSIQNHVITKNH-------RISISHTEHRIWQLKIRDVQESDRGW 110
            ||.|..| |||||.         ::.:|...|       |:.:.......:.|:|:.|...|.|.
  Rat    71 VVEDKNS-KVAWLN---------RSGIIFAGHDKWSLDPRVELEKRHALEYSLRIQKVDVYDEGS 125

  Fly   111 YMCQINT--DPMKSQMGYLDVVVPPDIVDYQTSQDVVRSTGQNVTLTCSATGVPMPTITWRREEA 173
            |.|.:.|  :|..||: ||.|.|||.|.:  .|.||..:.|.||||.|.|.|.|.|.||||  ..
  Rat   126 YTCSVQTQHEPKTSQV-YLIVQVPPKISN--ISSDVTVNEGSNVTLVCMANGRPEPVITWR--HL 185

  Fly   174 TPILISDDGDREVFSVEGQNLTLWQVQRSHMGAYLCIASNGVPPTVSKRVMLVVNFAPTIWTRYD 238
            ||:....:|:.|...:.|       :.|...|.|.|.|:|.|.....|:|.:.||:.||| |...
  Rat   186 TPLGREFEGEEEYLEILG-------ITREQSGKYECKAANEVSSADVKQVKVTVNYPPTI-TESK 242

  Fly   239 TIYVGLGQKLTLECITESQPASVNFWLRDSQLLQGG------SYESVSVDHVFRIVMRITLRPIT 297
            :.....|::.:|:|...:.||....|.||...:...      |.|..|         .:|:..:|
  Rat   243 SNEATTGRQASLKCEASAVPAPDFEWYRDDTRINSANGLEIKSTEGQS---------SLTVTNVT 298

  Fly   298 KRDFGEYICRAKNAMGQTD-------RII------------TVHHKAKKHGQHSHQTSSRESQFI 343
            :..:|.|.|.|.|.:|.|:       |::            |||.|.|..|.             
  Rat   299 EEHYGNYTCVAANKLGVTNASLVLFKRVLPTVPHPIQEIGTTVHFKQKGPGS------------- 350

  Fly   344 VIEEYIANMSDKSCSFQPLWIM---FLCFVNK 372
                 :..::.......|||::   ..|.::|
  Rat   351 -----VRGINGSISLAVPLWLLAASLFCLLSK 377

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-iotaNP_001097100.1 IG_like 39..125 CDD:214653 30/94 (32%)
Ig 39..122 CDD:299845 28/91 (31%)
Ig 132..213 CDD:299845 30/80 (38%)
IG_like 141..227 CDD:214653 31/85 (36%)
IG_like 239..322 CDD:214653 22/107 (21%)
IGc2 245..313 CDD:197706 18/73 (25%)
LsampXP_038944182.1 Ig 55..145 CDD:416386 32/100 (32%)
FR1 55..71 CDD:409353 6/15 (40%)
Ig strand A' 56..62 CDD:409353 3/5 (60%)
Ig strand B 64..72 CDD:409353 3/7 (43%)
CDR1 72..76 CDD:409353 2/3 (67%)
FR2 77..84 CDD:409353 6/16 (38%)
Ig strand C 77..83 CDD:409353 5/6 (83%)
CDR2 85..95 CDD:409353 2/9 (22%)
Ig strand C' 87..90 CDD:409353 1/2 (50%)
Ig strand C' 92..95 CDD:409353 1/2 (50%)
FR3 96..131 CDD:409353 8/34 (24%)
Ig strand D 100..107 CDD:409353 1/6 (17%)
Ig strand E 110..116 CDD:409353 1/5 (20%)
Ig strand F 123..131 CDD:409353 3/7 (43%)
CDR3 132..136 CDD:409353 1/3 (33%)
Ig strand G 136..145 CDD:409353 5/9 (56%)
FR4 138..145 CDD:409353 4/7 (57%)
Ig_3 148..218 CDD:404760 30/80 (38%)
Ig strand A' 155..160 CDD:409353 3/4 (75%)
Ig strand B 166..173 CDD:409353 4/6 (67%)
Ig strand C 179..184 CDD:409353 4/6 (67%)
Ig strand D 190..193 CDD:409353 0/2 (0%)
Ig strand E 197..203 CDD:409353 1/5 (20%)
Ig strand F 210..217 CDD:409353 3/6 (50%)
Ig strand G 224..232 CDD:409353 2/7 (29%)
Ig_3 235..311 CDD:404760 21/85 (25%)
Ig strand B 252..256 CDD:409353 1/3 (33%)
Ig strand C 265..269 CDD:409353 0/3 (0%)
Ig strand E 290..294 CDD:409353 1/12 (8%)
Ig strand F 304..309 CDD:409353 2/4 (50%)
Ig strand G 318..321 CDD:409353 0/2 (0%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166337169
Domainoid 1 1.000 45 1.000 Domainoid score I11853
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 142 1.000 Inparanoid score I4382
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D265311at33208
OrthoFinder 1 1.000 - - FOG0000150
OrthoInspector 1 1.000 - - mtm8971
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X97
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
109.800

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