DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-iota and Ncam2

DIOPT Version :9

Sequence 1:NP_001097100.1 Gene:DIP-iota / 33925 FlyBaseID:FBgn0031837 Length:376 Species:Drosophila melanogaster
Sequence 2:NP_981954.2 Gene:Ncam2 / 288280 RGDID:1303131 Length:837 Species:Rattus norvegicus


Alignment Length:340 Identity:83/340 - (24%)
Similarity:137/340 - (40%) Gaps:61/340 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    39 NSTVPVGRDALLTCVVHDLVSFKVAWLRVDTQTILSIQNHVITKNHRISI--SHTEHRIWQLKIR 101
            |:|...|.:..|||.........::|.|         ...:|.:|.:..:  |:||     |.:|
  Rat   219 NATAERGEEMTLTCKASGSPDPAISWFR---------NGKLIEENEKYILKGSNTE-----LTVR 269

  Fly   102 DVQESDRGWYMCQINTDPMKSQ-MGYLDVVVPPDIVDYQTSQDVVRSTGQNVTLTCSATGVPMPT 165
            ::...|.|.|:|:......:.| ..:|.|.|.|.|:  |...:.....| :|||.|.|.|.|:|.
  Rat   270 NIINKDGGSYVCKATNKAGEDQKQAFLQVFVQPHIL--QLKNETTSENG-HVTLICEAEGEPVPE 331

  Fly   166 ITWRREEATPILISDDGDREV---FSVEGQ----NLTLWQVQRSHMGAYLCIASNGVPPTVSKRV 223
            |||:|  |...:...:||:..   ..|:||    :|.:..|:.|..|.|.|.|::.:... .:.:
  Rat   332 ITWKR--AIDGVTFSEGDKSPDGRIEVKGQHGRSSLHIRDVKLSDSGRYDCEAASRIGGH-QRSM 393

  Fly   224 MLVVNFAPTIWTRYDTIYVGLGQKLTLECITESQPASVNFWLRDSQLLQGGSYESVSVDHVFRIV 288
            .|.:.:||...:.....|...|..:.:.|..::.|.:...|.|:..:|...:...:....|.| .
  Rat   394 HLDIEYAPKFVSNQTMYYSWEGNPINISCDVKANPPASIHWRREKLVLPAKNTTHLKTHSVGR-K 457

  Fly   289 MRITLRPITKRDFGEYICRAKNAMG--------------------------QTDRIITVHHKAKK 327
            |.:.:.|.:..|||.|.|.|.|.:|                          ||...|: .:|.:.
  Rat   458 MILEIAPTSDNDFGRYNCTATNRIGTRFQEYILELADVPSSPRGVKIIELSQTTAKIS-FNKPES 521

  Fly   328 HGQ---HSHQTSSRE 339
            ||.   |.:|...:|
  Rat   522 HGGVPIHHYQVDVKE 536

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-iotaNP_001097100.1 IG_like 39..125 CDD:214653 20/88 (23%)
Ig 39..122 CDD:299845 19/84 (23%)
Ig 132..213 CDD:299845 29/87 (33%)
IG_like 141..227 CDD:214653 27/92 (29%)
IG_like 239..322 CDD:214653 22/108 (20%)
IGc2 245..313 CDD:197706 17/67 (25%)
Ncam2NP_981954.2 IgI_1_NCAM-2 21..113 CDD:409452
Ig strand B 38..42 CDD:409452
Ig strand C 50..54 CDD:409452
Ig strand E 76..80 CDD:409452
Ig strand F 90..95 CDD:409452
Ig strand G 104..107 CDD:409452
IGc2 128..189 CDD:197706
Ig strand B 130..139 CDD:409353
Ig strand C 145..153 CDD:409353
Ig strand C' 156..159 CDD:409353
Ig strand D 162..167 CDD:409353
Ig strand E 168..175 CDD:409353
IgI_1_MuSK 209..298 CDD:409562 21/92 (23%)
Ig strand B 228..232 CDD:409562 1/3 (33%)
Ig strand C 241..245 CDD:409562 0/3 (0%)
Ig strand E 264..268 CDD:409562 3/8 (38%)
Ig strand F 278..283 CDD:409562 2/4 (50%)
Ig strand G 291..294 CDD:409562 1/2 (50%)
Ig 300..397 CDD:416386 31/102 (30%)
Ig strand A 300..305 CDD:409353 2/4 (50%)
Ig strand A' 309..313 CDD:409353 0/3 (0%)
Ig strand B 317..325 CDD:409353 4/7 (57%)
Ig strand C 331..337 CDD:409353 4/7 (57%)
Ig strand C' 340..343 CDD:409353 0/2 (0%)
Ig strand D 353..359 CDD:409353 1/5 (20%)
Ig strand E 362..368 CDD:409353 1/5 (20%)
Ig strand F 376..384 CDD:409353 4/7 (57%)
Ig strand G 387..397 CDD:409353 1/10 (10%)
Ig_3 401..479 CDD:404760 18/78 (23%)
Ig strand B 418..422 CDD:409353 0/3 (0%)
Ig strand C 431..435 CDD:409353 0/3 (0%)
Ig strand E 458..462 CDD:409353 1/3 (33%)
Ig strand F 472..477 CDD:409353 2/4 (50%)
Ig strand G 486..489 CDD:409353 0/2 (0%)
FN3 496..588 CDD:238020 9/42 (21%)
fn3 594..678 CDD:394996
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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